A study was conducted to determine the physiological baseline values for biochemical profile of Mehsana goat (Capra hircus) as well as to assess their alteration with age, sex and physiological stages. A total of 42 clinically healthy Mehsana goats were divided into seven groups with 6 number of animal per group: T1 (male kids 1 year), T3 (female kids 0.05) differ significantly. Serum albumin concentration was found to be (p < 0.05) higher in female kids than dry non-pregnant does. The results of the present study demonstrate the normal biochemical indices of Mehsana goat at different physiological stages. Present results stated some significant variation of parameters among groups whereas some shows no significant variation at all.