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Rawal Medical Journal
Periodical of Pakistan Medical Association Rawalpindi Islamabad Branch
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ISSN: 0303-5212 (Print)
Language: [ English ]  
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  » Volume 39, Issue 2
      pp. 113-241
  » Volume 39, Issue 1
      pp. 1-112

 

Open Access

Original Research



Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect

Haifa Ahmad Dasoky.

Abstract
Objective
To determine the clinical manifestation of congenital cytomegalovirus (CMV) infection and the effect of gancyclovir.
Methodology
Twenty newborns with congenital CMV infection were admitted at Queen Rania Hospital (KHMC) between January 2009 and December 2010 and were treated with Gancyclovir were included in the study.
Result
The most common clinical presentation was intrauterine growth retardation (45%), Hepatosplenomegaly (35%), Chorioretinites (35%) and purpuric skin rash (25%). Brain MRI was positive in 20%. Complete blood count was abnormal in 20%. More than 75% patients improved with gancyclovir without any complications.
Conclusion
Intrauterine growth retardation, hepatosplenomegaly and chorioretinites were commonest clinical manifestations of CMV infection. Gancyclovir was effective. Prevention of congenital CMV infection by immunization of symptomatic women who are at risk of primary infection during gestation should be emphasized. (Rawal Med J 2012;37:18-20).

Key words: Cytomegalovirus, gancyclovir, CMV.



How to Cite this Article
Pubmed Style

Dasoky HA. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. RMJ. 2012; 37(1): 18-20.



Web Style

Dasoky HA. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. www.scopemed.org/?mno=10844 [Access: August 27, 2014].



AMA (American Medical Association) Style

Dasoky HA. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. RMJ. 2012; 37(1): 18-20.



Vancouver/ICMJE Style

Dasoky HA. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. RMJ. (2012), [cited August 27, 2014]; 37(1): 18-20.



Harvard Style

Dasoky, H. A. (2012) Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. RMJ, 37 (1), 18-20.



Turabian Style

Dasoky, Haifa Ahmad. 2012. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. Rawal Medical Journal, 37 (1), 18-20.



Chicago Style

Dasoky, Haifa Ahmad. "Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect." Rawal Medical Journal 37 (2012), 18-20.



MLA (The Modern Language Association) Style

Dasoky, Haifa Ahmad. "Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect." Rawal Medical Journal 37.1 (2012), 18-20. Print.



APA (American Psychological Association) Style

Dasoky, H. A. (2012) Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. Rawal Medical Journal, 37 (1), 18-20.



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