The origin of Chronic airflow obstruction (CAO) syndrome in active Tuberculosis (TB), despite significant similarities with chronic obstructive pulmonary disease (COPD), still remains unknown. The aim of the study was to examine the potential causes and risks for the development of CAO syndrome in new cases of pulmonary TB. Design: Prospective, nest case-control study. Patients: 40 patients with newly detected cavitary pulmonary TB and initial normal respiratory function, diagnosed and treated according to DOTS strategy. Measurements and results: The average values of Snider’s radiological score during TB treatment were significantly reduced (p
tuberculosis, bronchial obstruction, risk factors, COPD.