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KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
Periodical of Yerküre
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ISSN: 1017-7833 (Print)
ISSN: 1302-9657 (Online)
Language: [ English ]  

  » Volume 15, Issue 4
      pp. 153-203
  » Volume 15, Issue 3
      pp. 93-152
  » Volume 15, Issue 2
      pp. 53-92
  » Volume 15, Issue 1
      pp. 1-52

 

Open Access

Case Report



Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report

Arzu Erkan, Sebnem Pirildar, Ahmet Acarer, Fisun Akdeniz.

Abstract
Tardive dyskinesia (TD) is a severe complication of antipsychotics. Pramipexole can be effective in the treatment of TD with its D3 dopamine receptor agonist effect. Studies conducted with bipolar depression and treatment-resistant depression (TRD); support the antidepressant effect of pramipexole. Here we present a 55-years-old female case. For the treatment of depression, she received antidepressant, anxiolytic and antipsychotics for 2,5 years. When severe bruxism, fidgeting, and serious functional impairment emerged, she was re-hospitalized and diagnosed with TRD and TD. Several combinations of antidepressant, anxiolytic, and antipsychotics were administered. The depression improved partially, but hypochondriac preoccupations and dyskinesia persisted. At the sixth month, pramipexole 0.125 mg/day was added to sertraline 200 mg/day, amitriptyline 60 mg/day, clonazepam 2 mg/day, and biperiden 4 mg/day. The depression and dyskinesia improved and she was discharged. TRD and TD improved within the first 4 weeks of pramipexole administration and no relapse was observed. Pramipexole is a promising agent in the treatment of TRD and TD.

Key words: Pramipexole, Depression, Psychotic; Dyskinesia, Drug-Induced



REFERENCES
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How to Cite this Article
Pubmed Style

Erkan A, Pirildar S, Acarer A, Akdeniz F. [Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]. KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY. 2011; 21(4): 1-2. Turkish. doi:10.5455/bcp.20111029071711



Web Style

Erkan A, Pirildar S, Acarer A, Akdeniz F. [Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]. www.scopemed.org/?mno=12261 [Access: August 30, 2016]. Turkish. doi:10.5455/bcp.20111029071711



AMA (American Medical Association) Style

Erkan A, Pirildar S, Acarer A, Akdeniz F. [Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]. KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY. 2011; 21(4): 1-2. Turkish. doi:10.5455/bcp.20111029071711



Vancouver/ICMJE Style

Erkan A, Pirildar S, Acarer A, Akdeniz F. [Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]. KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY. (2011), [cited August 30, 2016]; 21(4): 1-2. Turkish. doi:10.5455/bcp.20111029071711



Harvard Style

Erkan, A., Pirildar, S., Acarer, A. & Akdeniz, F. (2011) [Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]. KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, 21 (4), 1-2. Turkish. doi:10.5455/bcp.20111029071711



Turabian Style

Erkan, Arzu, Sebnem Pirildar, Ahmet Acarer, and Fisun Akdeniz. 2011. [Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]. KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, 21 (4), 1-2. Turkish. doi:10.5455/bcp.20111029071711



Chicago Style

Erkan, Arzu, Sebnem Pirildar, Ahmet Acarer, and Fisun Akdeniz. "[Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]." KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY 21 (2011), 1-2. Turkish. doi:10.5455/bcp.20111029071711



MLA (The Modern Language Association) Style

Erkan, Arzu, Sebnem Pirildar, Ahmet Acarer, and Fisun Akdeniz. "[Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]." KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY 21.4 (2011), 1-2. Print.Turkish. doi:10.5455/bcp.20111029071711



APA (American Psychological Association) Style

Erkan, A., Pirildar, S., Acarer, A. & Akdeniz, F. (2011) [Efficacy of Low-dose Pramipexole Augmentation in the Treatment of Refractory Psychotic Depression Complicated with Tardive Dyskinesia: A Case Report]. KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, 21 (4), 1-2. Turkish. doi:10.5455/bcp.20111029071711



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