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Review Article

Bipolar Disorder and Obsessive Compulsive Disorder Comorbidity

Necla Keskin, Lut Tamam.

The comorbidity of bipolar disorder and anxiety disorders is a well known concept. Obsessive-compulsive disorder is the most commonly seen comorbid anxiety disorder in bipolar patients. Some genetic variants, neurotransmitters especially serotonergic systems and second-messenger systems are thought to be responsible for its etiology. Bipolar disorder alters the clinical aspects of obsessive compulsive disorder and is associated with poorer outcome. The determination of comorbidity between bipolar disorder and obsessive compulsive disorder is quite important for appropriate clinical management and treatment.

Key words: Bipolar disorder, obsessive compulsive disorder, clinical management

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