Abstract
Adult-Onset Still’s Disease (AOSD) is a rare clinical entity with unknown etiology, characterized by arthritis, fever, evanescent rash and other systemic presentations. This report described a 24-year-old female who presented with sore throat, fever, raised liver enzymes and cervical lymphadenopathy. Later on patient developed evanescent skin rash and polyarthritis pointed to a possible rheumatological diagnosis. She was diagnosed to have AOSD based on Yamaguchi criteria after the exclusion of other potential diagnoses. Patient was treated with combinations of NSAID and DMARD leading to remission. So early and aggressive treatment can herald possible fatal deformity and sufferings.

Key words: Adult-onset Still’s disease, Arthritis, fever, Yamaguchi criteria