Journal Management System
ScopeMed is an
Online Journal/Article Management system
that can enable all of the operations of
the editorial functions of a journal.
Home  |   Add your Journal  |   Features  |   Job Opportunities/Service Offers  |   Journal List
Author Login | Reviewer Login | Editor Login
Search  

Rawal Medical Journal
Periodical of Pakistan Medical Association Rawalpindi Islamabad Branch
Journal Home Page
ISSN: 0303-5212 (Print)
Language: [ English ]  
News / Announcements

  » Volume 39, Issue 2
      pp. 113-241
  » Volume 39, Issue 1
      pp. 1-112

 

Open Access

Editorial



PPI safety concerns

Nasir Khokhar.

Abstract
Proton Pump Inhibitors (PPIs) are among the most prescribed therapeutic agents worldwide. Their role in management of acid related disorders and in critically ill patients at risk for the development of stress related mucosal bleeding is well established.1 However, reports on their safety have appeared recently. Hypochlorhydria, hypergastrinemia, interactions on hepatic cytochrome P450 enzymes, nutritional deficiencies, anemia, osteoporosis and bone fractures (especially vertebral), increased risk for pulmonary or enteric infections, polyp or tumor formation and risk of cardiovascular events in patients on PPIs and clopidogrel have been recent highlighted concerns.2 While there is considerable debate regarding the negative impact of concomitant PPIs therapy with clopidogrel, platelet function studies did not demonstrate a clear or consistent interaction between clopidogrel and PPIs.3

Key words: PPI, osteoporosis, pneumonia


ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Nasir Khokhar
on IndexScholar Fulltext
on Google
on Google Scholar
Article Statistics
 Viewed: 839
Downloaded: 242
(Last 7 Days: 3)
Cited: 0
Emailed: 0

How to Cite this Article
Pubmed Style

Khokhar N. PPI safety concerns . RMJ. 2012; 37(1): 1-1.



Web Style

Khokhar N. PPI safety concerns . www.scopemed.org/?mno=16747 [Access: July 31, 2014].



AMA (American Medical Association) Style

Khokhar N. PPI safety concerns . RMJ. 2012; 37(1): 1-1.



Vancouver/ICMJE Style

Khokhar N. PPI safety concerns . RMJ. (2012), [cited July 31, 2014]; 37(1): 1-1.



Harvard Style

Khokhar, N. (2012) PPI safety concerns . RMJ, 37 (1), 1-1.



Turabian Style

Khokhar, Nasir. 2012. PPI safety concerns . Rawal Medical Journal, 37 (1), 1-1.



Chicago Style

Khokhar, Nasir. "PPI safety concerns ." Rawal Medical Journal 37 (2012), 1-1.



MLA (The Modern Language Association) Style

Khokhar, Nasir. "PPI safety concerns ." Rawal Medical Journal 37.1 (2012), 1-1. Print.



APA (American Psychological Association) Style

Khokhar, N. (2012) PPI safety concerns . Rawal Medical Journal, 37 (1), 1-1.







Total Download: 221.232
(for Rawal Medical Journal)
Total Submission during last 24 hours: 161


» For Authors




Become Reviewer


» Login Area




Follow ScopeMed on Twitter

ScopeMed Home | About ScopeMed | Contact Us | Terms & Conditions | Privacy Policy
The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Service of SAGEYA Publishing for Scientific Publications. Copyright © ScopeMed® International Medical Journal Management and Indexing System.