Abstract
Current study was done to evaluate the histopathological findings in glomerulopathies and to correlate the histopathological findings with the clinical disease. Thirty cases of renal biopsy were studied. All biopsies were collected in Bouin’s fluid and processed routinely. Slides were stained routinely with hematoxylin and eosin (H and E). Periodic acid Schiff (PAS) and Methanamine silver (PASM) were done as and when required. Immunofluorescence was performed and was correlated with clinical and microscopic findings in all cases. Among thirty renal biopsies, primary glomerulonephritis accounted for 70% and secondary glomerulonephritis accounted for 30%. Among primary glomerulonephritis, most predominant lesion was focal segmental glomerulosclerosis(FSGS) (28.5%) and post infectious glomerulonephritis (28.5%) followed by minimal change disease(MCD) (14.3%), membranous glomerulonephritis (9.5%), crescentric glomerulonephritis (4.8%). membranoproliferative glomerulonephritis (4.8%), immunoglobulin A nephropathy (4.8%), chronic glomerulonephritis (4.8%). Among secondary glomerulonephritis predominant lesion was systemic lupus nephritis (66.7%) followed by diabetes mellitus (22.2%) and amyloidosis (11.1%). Among primary glomerulonephritis increase in occurrence of focal segmental glomerulosclerosis and post infectious glomerulonephritis was noted. Among secondary glomerulonephritis increase in occurrence of systemic lupus erythematosus was noted.

Key words: Histopathology, renal biopsy, glomerulopathies, primary glomerulonephritis, secondary glomerulonephritis