Abstract
Background: Night work is associated sleep deprivation, where the person’s internal body clock is in conflict with the rotating shift schedule leads to circadian disruption of various physiological rhythms like blood pressure, heart rate, and various hormones. Night shift workers have altered circadian pattern of blood pressure/heart rate. Due to this variation, night shift worker suffers from various cardiovascular and circadian rhythm disorders.
Objective: The Present study was aimed to investigate the effects of rotating night shift on 24 hours chronomics of blood pressure and heart rate in terms of double amplitude, acrophase and hyperbaric index.
Materials and Methods: 62 healthy nursing professionals, aged 20-40 year, performing day and night shift duties were recruited. This was the prospective observational study. Each month scheduled to continuous 9 days night shift (12 hours in regular 9 nights, from 20:00 to 08:00); after 9 days night shift they perform remaining duties in day shift and 4 days off in each month. Ambulatory BP and HR were recorded at every 30 min intervals in day time and each hour in night time during their day and night shift duties.
Results: Highly Significant difference was found in double amplitude (2DA) of blood pressure between night and day shift (p

Key words: Circadian rhythm, entrainment, rotating night shift.