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Estimation of glucose level and body weight in Alloxan Induced Diabetic Rat treated with Aqueous extract of Garcinia Kola Seed

Chinwe Ewenighi, Uchechukwu Dimkpa, Joel Onyeanusi, Linus Onoh, Gladys Onoh, Uchechukwu Ezeugwu.

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Aim: Hypoglyceamic effect of Garcinia kola (GK) was evaluated in alloxan induced diabetic rats.
Method: Eighteen male wistar albino rats of weights between 158-172g were divided into three groups A- C. Group A was given distilled water (D/W) throughout the experiment; diabetes was induced in group B and C. Group B was given d/w but not GK while group C was treated with GK extract for 21 days. Fasting blood samples were collected at baseline, 24 hours, 7th, 14th and 21st day for blood glucose evaluation.
Results: Mean fasting blood glucose (FBG) level was significantly higher (P

Key words: Garcinia kola, alloxan, glucose, diabetes mellitus, hypoglyceamia, hyperglyceamia

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Journal of Molecular Pathophysiology


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