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Egypt. J. Exp. Biol. (Zoo.). 2008; 4(0): 215-222


EFFECT OF OCCUPATIONAL EXPOSURE TO ELECTROMAGNETIC FLUX INDUCED BY HIGH VOLTAGE ELECTRIC FIELD ON HUMAN AND EXPERIMENTAL ANIMALS

Zohour I. Nabil, Aida A. Hussein, Mahmoud Abdel Kader, Salwa M. Metwaly.

Abstract
Recently, profound transformation in our physical environment including widespread of communication technology led to discharge of electromagnetic fields which adversely affected our health. The objective of this study is to investigate the cardiovascular effects of high voltage electric fields on rats, as well as humans occupationally exposed in electric stations. Working subjects were tested using general health questionnaires for neuro-prychiatric symptoms. Male albino rats were used for conducting this study. They were divided into four groups; five animals per each. The first group served as control while the other three were exposed to 10 kv EF for 12, 18 hours daily for 14 continuous days or with weekends, respectively. Electro-cardiograms (ECG) were recorded for both control and exposed animals. By the end of the sessions, rats were sacrificed and blood samples were taken for haematologic and blood chemistry analysis. Analysis of the ECGs showed that exposure induced significant changes in the recorded parameters; significant bradycardia accompanied by an increase in the P-R interval. In the meantime, significant decrease of the R amplitude depending on the exposure intervals was also noticed. Statistical analysis of the CBC revealed a significant decrease in leukocyte count. Meanwhile a significant increase in platelets count was reported. Serum analysis, glucose, cholesterol, Aspartate transaminase (AST), Creatine Kinase (CPK), and Lactate dehydrogenase (LDH) activities were significantly increased while calcium ions Ca+2 levels were markedly declined. Moreover, sodium ions Na+, Urea, Blood Urea Nitrogen (BUN), creatinine levels were significantly increased.

Key words: Electromagnetic Fields, Cardiovascular System, Rats, Human Occupationally Exposured



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