Background. Appendicitis is associated with high rate of wrong diagnosis.
Objective. To evaluate the predictive value of 5-HIAA in diagnosis of appendicitis.
Methods. Spot urine samples were collected from 147 patients with appendicitis and 45 healthy controls. 5-HIAA was detected in urine samples in all patients using ELISA method.
Results. The mean 5-HIAA level was 4.5 Ámol/mmol creatinine in healthy individuals, 5.8 Ámol/mmol creatinine in patients with wrongly diagnosed appendicitis, and 15.7 Ámol/mmol creatinine in patients with appendicitis. The difference between patients group with appendicitis and other 2 groups was statistically highly significant (P
Keywords: 5-HIAA, acute appendicitis, diagnosis.