Background: The incidence of Oral sub mucous fibrosis disease has been found to about 13% of the general population, varying from 0 to 4% depending on the geographic location, On epidemiological survey shows this disease was found in India especially in southern states with prevalence of 0.36% Ernakulum in Kerala, 0.4% in Srikakulam district in Andra Pradesh, 0.16% in Bhavnagar in Gujarat, 007% in Bihar and 0.03% in Maharashtra. The prime causes suspected are prolonged use of chilly (capsicum), betel nut, tobacco, alcohol, Pan-masala and Pan which are considered to be local factors. This study is one of the pioneer studies in the treatment of oral sub mucous fibrosis. Aim: The purpose of this study to assess the efficacy of the medical treatment modalities of oral sub mucous fibrosis and to evaluate the visceral organ involvement mainly cardiac in oral sub mucous fibrosis. Material and Method: The study consisted of 40 patients suffering from oral sub mucous fibrosis of various grades who were selected from outpatient department of oral medicine and radiology, Tamilnadu government dental college. On first visit of the patient, the selected patients were clinically divided in to various grades based on the clinical grading by Gupta et al. Result: Study was observed, statically proved and that combined therapy employing nutritional and iron supplement with intralesional injection therapy using Hyaluronidase, Dexamethasone, and Placentrex and topical application of Triamcinolone Acetonide 0.1% caused a marked improvement in the patient. Conclusion: patients signs and symptoms evidenced by increase the mouth opening, increase in tongue protrusion, improvement in the patient colour of mucosa.
Oral sub mucous fibrosis, chronic disease