Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Research

RMJ. 2016; 41(3): 295-299

Prevalence of vitamin B12 deficiency in patients with type 2 diabetes taking metformin: a developing country perspective

Pawan Kumar, Amrat Kumar, Muhammed Tanveer Alam, Arvind Kumar Sharda, Tazeen Rasheed, Muhammed Aurangzeb, Muhammed Masroor.

Objective: To determine the prevalence of vitamin B12 deficiency in patients with type 2 diabetes taking metformin attending a tertiary care facility.
Methodology: This cross-sectional study was conducted at Diabetic OPD, Civil Hospital, Karachi, from January 2012 to July 2012. Patients of 35 to 60 years of age with type 2 Diabetes Mellitus (DM) and compliant with metformin (≥500 mg/day) for more than 3 years were included. Patients with partial or total gastrectomy, pernicious anemia, Crohn’s disease, on supplemental vitamin B12, and strict vegetarians were excluded. Brief history regarding the duration of DM, duration of metformin use, daily dose of metformin, mean blood sugar levels and monthly family income was taken. One blood sample from each patient was obtained to determine vitamin B12 level. Vitamin B12 deficiency was defined as serum level 50 years of age, 16 (30.1%) were 40-50 years of age and 6 (11.30%) were

Key words: Biguanides, diabetes mellitus, vitamin B12, metformin, megaloblastic anemia.

Share this Article

Journal of Behavioral Health


ScopeMed Home
Follow ScopeMed on Twitter
Article Tools
eJPort Journal Hosting
About ScopeMed
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.
Scopemed Buttons