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Original Research

RMJ. 2016; 41(3): 346-350


Effects of gender in automated urinalysis test results as predictors of true urinary tract infection in infants

Kağan Huysal, Yasemin Üstündağ Budak, Murat Tutanc, Nihat Kutluay, Hakan Erdoğan.

Abstract
Objective: We sought to evaluate whether there is a gender difference for IRIS IQ200 test results as rapid diagnostic test in rouling out culture positivity in infants in a routine hospital laboratory.
Methodology: This retrospective cohort study utilized data from 2159 unselected consecutive patients aged 1 month to 1 year, who attended the Sevket Yilmaz Research and Education Hospital from January to December 2014 and received both urinalysis and culture for suspected UTI. A sample was considered culture-positive if it contained a pure culture of ≥ 50,000 104 CFU/mL. 272 patients, 39 culture positive and 233 culture negative females (median age 6 months), and 280 male patients, 28 culture positive and 252 culture negative, (median age 4 months) were evaluated.
Results: Nitrite alone had a PPV of 95% and an NPV of 90.9% in the infant group. PPV and SP were 100% in male infants. A positive leukocyte count (≥4 cells/HPF) had a specificity of 90%, a PPV of 46.6% and an NPV of 94.5% in infants, which was 94.3 in boys. LE alone had higher specifity (95.1%), PPV (53.8%) and NPV (94.4%) in boys compared to girls, 89.2%, 50.0% and 94.4%
Conclusions: The results of urine tests should not be used alone for the diagnosis of UTI in infant without gender difference.

Key words: Urinary Tract Infections, Gender, Leukocytes, Infant, Microscopy



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