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Original Research

J Clin Exp Res. 2015; 3(3): 201-205

Prevalence and antibacterial drug sensitivity pattern of Pseudomonas aeruginosa in tertiary care hospital in Jamnagar region, Gujarat, India

Prakash S. Modi, Swati D. Jethava, Awadhesh Kumar, Ruchi R. Sanghavi.

Background: Pseudomonas aeruginosa is ranked as fourth common causes of hospital acquired infection responsible for high morbidity and mortality rate. It is highly prevalent in hospital environment and in critically ill patients. Objectives: To evaluate the prevalence and antibacterial drug sensitivity pattern of P. aeruginosa, isolated from different clinical samples from human in Jamnagar region. Methods: All the samples were cultured on nutrient agar, blood agar and Mac Conkey agar followed by identification of P. aeruginosa isolates. All the P. aeruginosa isolates were subjected to antibacterial drug sensitivity test according to the Clinical Laboratory Standards Institute (CLSI) guidelines with quality controls (P. aeruginosa ATCC 27853). Result: Total 3880 samples were tested, from April 2015 to September 2015 at Dept. of Microbiology, Shri M. P. Shah Government Medical College and G.G. Government Hospital, Jamnagar. P. aeruginosa isolates were identified in 170 samples out of 3880 samples which shows the 4.38% prevalence. Most common age infected with P. aeruginosa was between 40-60 years (38.82%) and males (57.65%) were more prone to infection than females (42.35%). Maximum numbers of P. aeruginosa (50.00%) were present in pus/wound and in surgery department with 35.88% cases. Isolates were most sensitive to pipericillin + tazobacam (68.82%) followed by almost same sensitivity rate to other antibiotics like levofloxacin (43.53%), cefotaxime (43.53%), ceftazidime (42.94%), amikacin (42.94%) imipenam (40%) and aztreonam (40%). Conclusion: P. aeruginosa is emerged as multi drug resistant microbes, so susceptibility pattern is suggested to clinician prior to prescribing antibiotics to patients.

Key words: Antibacterial drug sensitivity, Jamnagar region, P. aeruginosa, prevalence

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