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Medical Archives
Periodical of AVICENA, d.o.o., Sarajevo
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ISSN: 0350-199X (Print)
ISSN: 1986-5961 (Online)
Language: [ English ]  
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Original Research



Osteoarticular Manifestations of Brucellosis

Snjezana Mehanic, Rusmir Baljic, Velida Mulabdic, Ilhama Huric-Jusufi, Fikret Pinjo, Jasna Topalovic-Cetkovic, Vesna Hadziosmanovic.

Abstract
Introduction: Osteoarticular manifestations of human brucellosis occur in 20-40% of patients while spondylodiscitis is the most severe form of the bone and joint structures involvements. Aim: The aim of this paper is tho show clinical and radiological caracteristics of osteoarticular forms of brucellosis, with special reference to spondylodiscitis. Material and methods: The medical histories of 120 hospitalized patients at the Clinic for Infectious Diseases, Clinical Center of Sarajevo University, diagnosed with brucellosis, were analyzed. Results: Osteoarticular manifestations had sixty-nine patients, representing 78.4% of all localized forms of the disease. Spondylodiscitis represents 40.6% of all osteoarticular manifestations of the disease. Nine patients (32.1%) had paravertebral and paraspinal abscess. Median diagnostic interval for spondylodiscitis (116±160 days) was almost twice prolonged compared to the arthritis and sacroilitis (p<0.05). The most common radiological manifestations were erosions of the vertebral surface (67.8%). Computerized tomography confirmed inflammation in 85.2% of the patients, while magnetic resonance imaging (MRI) showed radiological alterations in all patients (100%). Discussion and conclusion: Osteoarticular manifestations are the most common localised forms of brucellosis. The frequency of spondylodiscitis is in relation to duration of the diagnostic time. MRI shows a high degree of sensitivity to inflammatory changes of spine and „Pedro Pons’ sign“ is patognomic radiological alteration.

Key words: brucellosis, osteoarticular manifestations, spondylodiscitis.


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How to Cite this Article
Pubmed Style

Mehanic S, Baljic R, Mulabdic V, Huric-Jusufi I, Pinjo F, Topalovic-Cetkovic J, Hadziosmanovic V. Osteoarticular Manifestations of Brucellosis . Med Arh. 2012; 66(Suplement 1): 24-26. doi:10.5455/medarh.2012.66.s24-s26



Web Style

Mehanic S, Baljic R, Mulabdic V, Huric-Jusufi I, Pinjo F, Topalovic-Cetkovic J, Hadziosmanovic V. Osteoarticular Manifestations of Brucellosis . www.scopemed.org/?mno=22471 [Access: July 24, 2014]. doi:10.5455/medarh.2012.66.s24-s26



AMA (American Medical Association) Style

Mehanic S, Baljic R, Mulabdic V, Huric-Jusufi I, Pinjo F, Topalovic-Cetkovic J, Hadziosmanovic V. Osteoarticular Manifestations of Brucellosis . Med Arh. 2012; 66(Suplement 1): 24-26. doi:10.5455/medarh.2012.66.s24-s26



Vancouver/ICMJE Style

Mehanic S, Baljic R, Mulabdic V, Huric-Jusufi I, Pinjo F, Topalovic-Cetkovic J, Hadziosmanovic V. Osteoarticular Manifestations of Brucellosis . Med Arh. (2012), [cited July 24, 2014]; 66(Suplement 1): 24-26. doi:10.5455/medarh.2012.66.s24-s26



Harvard Style

Mehanic, S., Baljic, R., Mulabdic, V., Huric-Jusufi, I., Pinjo, F., Topalovic-Cetkovic, J. & Hadziosmanovic, V. (2012) Osteoarticular Manifestations of Brucellosis . Med Arh, 66 (Suplement 1), 24-26. doi:10.5455/medarh.2012.66.s24-s26



Turabian Style

Mehanic, Snjezana, Rusmir Baljic, Velida Mulabdic, Ilhama Huric-Jusufi, Fikret Pinjo, Jasna Topalovic-Cetkovic, and Vesna Hadziosmanovic. 2012. Osteoarticular Manifestations of Brucellosis . Medical Archives, 66 (Suplement 1), 24-26. doi:10.5455/medarh.2012.66.s24-s26



Chicago Style

Mehanic, Snjezana, Rusmir Baljic, Velida Mulabdic, Ilhama Huric-Jusufi, Fikret Pinjo, Jasna Topalovic-Cetkovic, and Vesna Hadziosmanovic. "Osteoarticular Manifestations of Brucellosis ." Medical Archives 66 (2012), 24-26. doi:10.5455/medarh.2012.66.s24-s26



MLA (The Modern Language Association) Style

Mehanic, Snjezana, Rusmir Baljic, Velida Mulabdic, Ilhama Huric-Jusufi, Fikret Pinjo, Jasna Topalovic-Cetkovic, and Vesna Hadziosmanovic. "Osteoarticular Manifestations of Brucellosis ." Medical Archives 66.Suplement 1 (2012), 24-26. Print. doi:10.5455/medarh.2012.66.s24-s26



APA (American Psychological Association) Style

Mehanic, S., Baljic, R., Mulabdic, V., Huric-Jusufi, I., Pinjo, F., Topalovic-Cetkovic, J. & Hadziosmanovic, V. (2012) Osteoarticular Manifestations of Brucellosis . Medical Archives, 66 (Suplement 1), 24-26. doi:10.5455/medarh.2012.66.s24-s26







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