Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Research

Association of serum free iron and glycemic control among type II diabetes mellitus population in Puducherry a preliminary study

Muraliswaran Perumal, Arun Muthukumar G Lakshmanan, Kanagavalli Prasanna Ragavan, Radhika Ravi.

Background: Iron modify glucose metabolism and glucose metabolism impinges on iron. Glycation of hemoglobin contributes to substantial affinity for transitional metals and the development of complications is linked to the accumulation of glycation.

Objective: This study was undertaken to assess the serum free iron levels in patients with type II diabetes mellitus (DM) and its correlation with good and poor glycemic control.

Materials and Methods: An analytical cross-sectional study was conducted among 100 patients and 50 healthy controls. They are grouped as Group I, 50 normal healthy controls; Group II, 50 type II DM patients with good glycemic control (HbA1C ≤ 7); Group III, 50 type II DM patients with poor glycemic control (HbA1C > 7). Levels of HbA1C l and serum iron were assessed. The data collected were recorded and analyzed using SPSS version 16.0.

Result: The mean serum iron concentration between group I and III (p < 0.001) as well as between group II and III (p < 0.005) was statistically significant. Difference between group I and II was not statistically significant (p = 0.205).

Conclusion: From our study it was concluded that serum free iron concentration was higher in patients with type II DM with poor glycemic control. In addition, there was a positive correlation between serum free iron concentration and glycemic control.

Key words: Serum free iron, glycated haemoglobin, type-II diabetes mellitus, glycemic control

Share this Article

Journal of Contemporary Medical Education


ScopeMed Home
Follow ScopeMed on Twitter
Article Tools
eJPort Journal Hosting
About ScopeMed
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons