Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Research

Qualitative and quantitative changes of corneal endothelial cells and central corneal thickness in pseudoexfoliation syndrome and pseudoexfoliation glaucoma

Saroj Sarowa, Jaishri Murli Manoher, Kalpana Jain, Yamini Singhal, Deepak Devathia.

Background: Pseudoexfoliation syndrome (PXS) is age-related systemic microfibrillopathy, caused by gradual deposition of extracellular grey and white material over various tissues. PXS is frequently associated with secondary open angle glaucoma. In Pseudoexfoliation eyes, corneal endothelial changes have been reported. The present study analysed corneal endothelial morphometry and central corneal thickness in PXS and pseudoexfoliation glaucoma.

Objective: To evaluate qualitative and quantitative changes of corneal endothelial cells and central corneal thickness in pseudoexfoliative(PEX) eyes with and without glaucoma and to compare with normal eyes and eyes with primary open-angle glaucoma(POAG).

Materials and Methods: A total of 80 patients were included in this study: 20 eyes with PXS, 20 eyes with pseudoexfoliation glaucoma(PXG), 20 eyes with POAG, and 20 normal eyes. Corneal endothelial cell density(ECD), coefficient of variation(CV) in cell size, percentage of hexagonal cells and central corneal thickness were measured using a non-contact specular microscope.

Results: ECD (p-value

Key words: Corneal endothelium, Central corneal thickness, Pseudoexfoliation Glaucoma Pseudoexfoliation Syndrome, Specular Microscopy

Share this Article

American Journal of Research in Medical Sciences


ScopeMed Home
Follow ScopeMed on Twitter
Article Tools
eJPort Journal Hosting
About ScopeMed
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons