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A Recurrence Biphasic Pulmonary Blastoma After Adjuvant Chemotherapy : A Case Report Of Rare Lung Malignancy

Asmaa Lakhdissi, Ibrahim Elghissassi, Khadija Bellahammou, Salif Balde, Sarra Akla, Mustapha Azakhman, Fouad Zouaidia, Najat Mahassini, Fadoua Rais, Nourredine Benjaafer, Hind Mrabti, Hassan Errihani, Mila Kayryakova, Ivan Inkov.

Abstract
Pulmonary Blastoma is a rare malignant lung tumor. The Biphasic pulmonary blastoma is composed of a mixture of immature epithelial and mesenchymal tissue ressembling fetal lung tissue with poor prognosis . The surgery is the treatment of choice. The strategy of treatment remains unclear due to the rarity of this tumor. We report a case of 26 year old women presenting with biphasic pulmonary blastoma who was treated with surgery and 6 cycles of adjuvant chemotherapy Etoposide-Cisplatine. Before she underwent adjuvant radiotherapy due to the positive margins, she developed dyspnea and the CT scan showed a massive local recurrence tumor compressing the heart. The patient received a palliative radiotherapy in the chest at the dose of 20Gy followed by palliative chemotherapy based on Adriamycin and Ifosfamide.

Key words: Biphasic pulmonary blastoma, chemotherapy, Radiotherapy



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