Abstract
Palmar-Plantar Erythrodysesthesia (PPE) (or) Burgdorf’s Reaction (BR) (or) Hand-Foot Syndrome (HFS) is the most common and dose limiting reversible dermatologic adverse reaction induced by anticancer chemotherapy. We report two cases of palmar-plantar erythrodysesthesia (or) hand-foot syndrome of varying degree of severity induced by capecitabine.

Key words: Burgdorf’s reaction, Capecitabine, Hand foot syndrome, Palmar-Plantar erythrodysesthesia