Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access


RMJ. 2016; 41(4): 519-521

Experience of GLP-1 agonist Exenatide in the management of type 2 diabetic obese Pakistani patients

Osama Ishtiaq, Rida Kamal, Tahir Iqbal, Batool Zehra.

Objective: We evaluated the use of Exenatide in terms of weight reduction and improvement of glycemic control, in patients with type 2 diabetes and obesity from Pakistan. Methodology: The study was done in Shifa International Hospital, Islamabad from year 2013 to 2014. Exenatide was prescribed to 45 patients, in which 19 patients had completed follow-ups. HbA1c, BMI and weight were recorded before and after the treatment. Side effects and reason for early discontinuation were also noted. Results: The concurrent use of Exenatide along with other anti-diabetic medications, enabled patients to reduce an average weight of 6.6kg (average decrease in BMI was 1.82kg/m2) and HbA1c levels of 0.6% over a period of 5 months, making it a promising therapeutic agent in obese and diabetic patients. The most common side effect noted was nausea. Conclusion: Exenatide has a potential to achieve reasonable weight loss and mild improvements in glycemic control in Pakistani obese and diabetic patients.

Key words: Exenatide, diabetes mellitus, obesity, GLP-1 agonist

Share this Article

Oxidants and Antioxidants in Medical Science


ScopeMed Home
Follow ScopeMed on Twitter
Article Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons