Home    eJManager.com Add Your Journal   |    Follow on Twitter   |    Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research



A series of 6 cases of systemic lupus erythematosus in pregnancy

Shruti Ashok Panchbudhe, Meena Naresh Satia, J. Madhavi.

Abstract
Background: Systemic lupus erythematosus (SLE) is a type of chronic inflammatory connective tissue disease commonly diagnosed between the ages of 20-30 It is more common in women than in men, especially during the fertile period of a women’s life. In olden days pregnancy in patients with SLE were discouraged due to concern regarding the poor feto-maternal outcomes. However, over the last 10-15 years, medical practice has changed, and in many cases pregnancy is possible with close supervision, and advice tailored according to individual cases. This case series will explain what care need to be taken into consideration prior to conception, ANC period and post pregnancy 100.
Methods: This was a retrospective study conducted at Seth G. S. M. C. and KEM Hospital Parel after IEC approval where 6 cases of Systemic Lupus Erythematosus in pregnancy over a period of 1 year in a unit were collected and are presented here with regards to maternal and fetal outcomes.
Results: In our case series two patients required Caesarean section for fetal indication and both the babies had congenital heart block and were asked regular follow up in cardiology outpatient department, two patients required medical termination of pregnancy in view of teratogenic drug exposure(cyclophosphamide), one patient had intrauterine growth restriction and had a preterm vaginal delivery with good fetal outcome and no heart block in the baby and the last patient was diagnosed as a case of SLE when baby was found to have heart block in the antenatal period and was later evaluated and diagnosed as a case of SLE.
Conclusions: Lupus activity is increased in pregnancy and patients with SLE are at higher risk for spontaneous abortions, fetal death, PIH, preterm delivery and intrauterine growth retardation. Management of these cases requires a multidisciplinary approach involving the obstetrician, rheumatologist, nephrologist and neonatologist.

Key words: Neonatal lupus syndrome, Systemic lupus erythematosus


Full text links

Share this Article




ScopeMed Home
Follow ScopeMed on Twitter
Article Tools
Job Opportunities/Service Offers
eJManager OJMS
eJPort Journal Hosting
About ScopeMed
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Service of eJManager LLC Publishing for Scientific Publications. Copyright © ScopeMedź Information Services.
Scopemed Buttons