Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

1



Clinical and epidemiological profile of chronic kidney disease patients in a tertiary care referral centre in South India

Swaraj Sathyan, Sunil George, Poornima Vijayan, Jayakumar M..

Abstract
Background: The clinical course of CKD (chronic kidney disease) is typically a progressive loss of nephron function ultimately leading to end stage renal disease (ESRD) requiring some form of renal replacement therapy. As this puts a significant burden on global resources, planning for prevention of CKD by early identification of kidney damage by identifying and screening high-risk individuals is the most practical solution. Aim: To study the clinico-epidemiological profile of newly diagnosed cases of CKD.
Methods: This study was conducted between January 2008 and June 2008 at a Government tertiary referral institution in South India. All newly diagnosed cases of CKD based on the National Kidney foundation definition were included in this study.
Results: Of the total 333 patients included in the study, 217 (65%) were males and 116 (35%) were females. Majority (275, 82.59%) of the patients were between 21-60 years of age. Chronic glomerulonephritis was by far the most common etiological diagnosis (51%) followed by diabetic nephropathy (22%) and hypertensive nephrosclerosis (7%) . About 24% had diabetes mellitus while 84% of the patients had hypertension. Dyspnea (75.68%), symptoms suggestive of volume overload in 242 (72.7%) and Oliguria (69%) were the chief presenting complaint. An overwhelming majority of the patients in the study presented in stage 5 CKD (264, 79.2%). 167 (50.15%) patients were found to have some form of cardiovascular disease. Cigarette smoking was prevalent in 32.7%, alcohol consumption in 6.91%, NSAID use in 5.1% and herbominerals in 4.5% .The mean hemoglobin in the study was 8.42 g/dl. Mean phosphate level in the study was 5.94 mg/dl. There was significant statistical correlation between hemoglobin level and stage of CKD and also between serum phosphate level and stage of CKD.
Conclusions: Early detection of CKD by screening of high risk individuals will go a long way in retarding the progression of ESRD. This will help in bringing down the huge burden due to mismatch between demand and availability of resources for renal replacement therapy in developing countries like India, especially for patients belonging to lower socioeconomic group.

Key words: CKD, Clinical profile, Epidemiological profile, ESRD, Etiology of CKD, Risk factors



Share this Article


Advertisement
Applied Medical Research

SUBMIT YOUR ARTICLE NOW




ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Article Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons