Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Original Article

Computational identification of miRNAs and their targets from Niger (Guizotia abyssinica)

K. Y. Prathiba, S. Usha, B. Suchithra, M. N. Jyothi, V. R. Devaraj, R. Nageshbabu.

MicroRNAs play a pivotal role in regulating a broad range of biological processes, acting by cleaving mRNAs or by translational repression. A group of plant microRNAs are evolutionarily conserved; however, others are expressed in a species-specific manner. In this study we used homology-based analysis with available expressed sequence tag (EST) of Niger (Guizotia abyssinica) to predict conserved miRNAs. Two potent miRNAs targeting 49 genes were identified. The newly identified miRNAs belongs to miR2592 and miR396 family. Targets recognized were F-box proteins, luecine zipper, DEAD box RNA helicase, disease resistant proteins. Gene annotations revealed miRNAs were involved in growth and development and Encyclopaedia of Genes and Genomes (KEGG) pathway analyses showed miRNAs were involved in metabolic pathways.

Key words: EST; GO analysis; miRNA; Transcription factors

Share this Article

American Journal of Physiology, Biochemistry and Pharmacology


ScopeMed Home
Follow ScopeMed on Twitter
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons