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To determine the eficacy of DIPSI as a method to screen GDM

Rashmi K., Anusha G. K..

Background: Gestational Diabetes Mellitus (GDM) is considered as a transient abnormality of glucose intolerance during pregnancy. Women with GDM and their children are at increased risk of future diabetes. The diagnosis of GDM gives us a unique opportunity in identifying individuals who will be benefited by early therapeutic intervention with diet, exercise and normalizing the weight to delay or possibly even prevent the onset of the disease. The objective of the study was to detect efficacy of Diabetes In Pregnancy Study Group of India (DIPSI) recommended 75g oral glucose challenge test in screening and diagnosis of GDM.
Methods: 200 pregnant women attending antenatal clinic during 24-28 weeks of pregnancy were subjected to Diabetes In Pregnancy Study Group of India (DIPSI) recommended 75g oral glucose challenge test (OGCT) as a method to screen and diagnose GDM. All patients were given 75grams of glucose irrespective of the meal and 2 hour venous blood sample was collected. Blood glucose was tested by GOD-POD (glucose oxidase peroxidise) method. Diagnosis of impaired glucose tolerance was made when plasma glucose of ≥120-140mg/dl and diagnosis of GDM was made when the plasma glucose of >140 mg/dl. All of them were followed up till delivery. Descriptive statistics was used to calculate the mean and standard deviation to draw the conclusion of this study.
Results: Out of the 200 women subjected to DIPSI recommended 75grams of OGCT 38 %, 40% and 22 % had normal, impaired and abnormal OGTT results, respectively. Age ≥25yrs, family history of diabetes and BMI ≥25kg/m2 are the commonest risk factors for GDM in the study group.
Conclusions: Our study supports the concept of universal screening and the use of DIPSI recommended 75g OGCT for screening and diagnosis of GDM.

Key words: DIPSI, GDM, OGCT

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