Ocimum sanctum (OS) is used for its varied medicinal properties. The present study was undertaken to evaluate the effect of OS on serum concentration of thyroid hormones and atherogenic profile in rabbits. Rabbits were divided into 2 groups of 10 each. Group I (Control): Standard chow diet. Group II (Test): maintained on same diet which control group rabbits received along with supplementation of 2 gm fresh leaves of Ocimum sanctum orally/day for 30 days. After 30 days in the rabbits receiving Ocimum sanctum, marked increase in the levels of T3 and T4 was observed where as TSH levels were significantly reduced as compared to control group. There was an improvement in the atherogenic profile in the test group. Ocimum sanctum can be used as adjunctive therapy for the regulation of thyroid functions and with hypolipidemic drugs.
Ocimum Sanctum, TSH, T3, T4, atherogenic profile.