Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles

Open Access

Review Article

IJHSR. 2016; 6(12): 302-310

Congenital Adrenal Hyperplasia in Saudi Arabia.

Nasir A.M. Al Jurayyan.

Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder resulting from a deficiency of one of the enzymes necessary for cortisol synthesis. As a result, decreased cortisol synthesis, increased adrenocorticotropin (ACTH) hormone via negative feedback system and over production of the hormones prior to the enzymatic defect. It is not a rare disorder in Saudi Arabia, where more than 90% of cases are due to 21-hydroxylase deficiency. Variable clinical forms ranging from the severe classical CAH, associated with complete loss of enzyme function to the milder non-classical forms (NCAH) where encounter.
This review presents an overview of the various types of CAH in Saudi Arabia, particularly the most common type 21-hydroxylase deficiency, highlighting its epidemiology, clinical presentation, diagnosis and management.

Key words: Congenital adrenal hyperplasia, cortisol deficiency, Androgen excess, epidemiology, Management, Saudi Arabia.

Share this Article

Journal of Interdisciplinary Histopathology


ScopeMed Home
Follow ScopeMed on Twitter
Article Tools
eJPort Journal Hosting
About ScopeMed
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons