Radicular cyst is the most common cystic lesion in the jaws, which is always associated with non-vital tooth. It arises from the epithelial residues within the periodontal ligament as a result of inflammation. The occurrence of ciliated, vacuolated, or mucous cells in odontogenic lesions is rare, but a well-recognised phenomenon. They are more commonly seen in maxillary lesions (21%) than mandibular lesions (14%). Metaplastic changes into these forms are found in the epithelial lining of radicular cysts, commonly on the surface layer. The pathological basis for this transition is poorly understood. We hereby present a case of radicular cyst with unusual changes in the epithelial lining, in a 29 year old female patient.
Radicular Cyst, Vacuolated Cell, Metaplasia, Mucous Cell.