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Case Report

IJHSR. 2016; 6(12): 368-371


A Rare Case Report on Chronic Neutrophilic Leukemia with Review of Literature.

Priyanka Gupta, Kishore Shaw, Raka Hota, Sukumar Chakravarty.

Abstract
Chronic neutrophilic leukemia (CNL) is a very rare myeloproliferative neoplasm (MPN) of elderly characterized by sustained neutophilic leucocytosis (>25000/cumm). Considering its rare entity, herein we report a case of CNL in an 80year old man who presented with dyspnoea, pleurisy and PUO. Persistent neutrophilic leukocytosis in a case of PUO in an elderly patient similar to this case can lead to a mistaken underdiagnosis. Suspicion is therefore required, to diagnose a case as CNL, if a patient presents with sustained neutrophilic leukocytosis without any underlying cause, not responding to higher antibiotics.

Key words: CNL, MPN, PUO, Sustained neutrophilic leukocytosis.



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