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Veterinary World
Periodical of Veterinary World
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ISSN: 0972-8988 (Print)
ISSN: 2231-0916 (Online)
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Open Access

Original Research



Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches

Basanti Jena, K. Sadasiva Rao, K. C. S. Reddy, K. B. P. Raghavender.

Abstract
Aim: The current study was done to study the therapeutic effect of natural prostaglandin in treatment of canine pyometra.

Materials and Methods: Seven bitches were treated with natural PGF2 á i.e. dinoprost tromethamine at the dose rate of 100 μg/kg body weight subcutaneously once daily for 7 days with supportive therapies. The physiological, haematological and biochemical parameters were studied before (0th day) and after treatment (8th day). Therapeutic efficacy was assessed in terms of return of abnormal parameters to either normal or near normal value as compared to the untreated control group, intensity of side effects and post treatment reproductive status.

Results: All physiological, haematological and biochemical parameters in the seven treated bitches returned to normal range at the end of treatment. The intensity of side effects was quite severe in the treatment group. Six bitches came to estrus within 2 months of treatment and out of them four conceived on subsequent mating. In rest three bitches there was recurrence of pyometra within 4 months of treatment.

Conclusion: Though conception rate of recovered bitches is decreased when compared with that of normal healthy bitches still this treatment protocol can be used successfully in treatment of canine pyometra to conserve the breeding capability of bitches.

Key words: bitch, prostaglandin, pyometra, therapeutic efficacy



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How to Cite this Article
Pubmed Style

Jena B, Rao KS, Reddy KCS, Raghavender KBP. Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches. Vet World. 2013; 6(6): 295-299. doi:10.5455/vetworld.2013.295-299



Web Style

Jena B, Rao KS, Reddy KCS, Raghavender KBP. Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches. www.scopemed.org/?mno=25269 [Access: September 14, 2014]. doi:10.5455/vetworld.2013.295-299



AMA (American Medical Association) Style

Jena B, Rao KS, Reddy KCS, Raghavender KBP. Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches. Vet World. 2013; 6(6): 295-299. doi:10.5455/vetworld.2013.295-299



Vancouver/ICMJE Style

Jena B, Rao KS, Reddy KCS, Raghavender KBP. Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches. Vet World. (2013), [cited September 14, 2014]; 6(6): 295-299. doi:10.5455/vetworld.2013.295-299



Harvard Style

Jena, B., Rao, K. S., Reddy, K. C. S. & Raghavender, K. B. P. (2013) Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches. Vet World, 6 (6), 295-299. doi:10.5455/vetworld.2013.295-299



Turabian Style

Jena, Basanti, K. Sadasiva Rao, K. C. S. Reddy, and K. B. P. Raghavender. 2013. Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches. Veterinary World, 6 (6), 295-299. doi:10.5455/vetworld.2013.295-299



Chicago Style

Jena, Basanti, K. Sadasiva Rao, K. C. S. Reddy, and K. B. P. Raghavender. "Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches." Veterinary World 6 (2013), 295-299. doi:10.5455/vetworld.2013.295-299



MLA (The Modern Language Association) Style

Jena, Basanti, K. Sadasiva Rao, K. C. S. Reddy, and K. B. P. Raghavender. "Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches." Veterinary World 6.6 (2013), 295-299. Print. doi:10.5455/vetworld.2013.295-299



APA (American Psychological Association) Style

Jena, B., Rao, K. S., Reddy, K. C. S. & Raghavender, K. B. P. (2013) Therapeutic efficacy of natural prostaglandin in the treatment of pyometra in bitches. Veterinary World, 6 (6), 295-299. doi:10.5455/vetworld.2013.295-299



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