Objective: To find the prevalence of different sonographic stages among newly diagnosed cases of chronic
Study Design: Cross sectional study.
Places and Duration of Study: Armed Forces Institute of Radiology and Imaging Rawalpindi, from June 2014 to
Material and Methods: All freshly diagnosed patients of chronic hepatitis C (CHC) with a positive anti-HCV and
a positive PCR for HCV were subjected to ultrasound abdomen. The sonographic stage of CHC was decided as
per previously defined criteria. Prevalence of each sonographic stage at the time of initial diagnosis was
determined. Study population was divided in two groups of 'Early stage CHC' (sonographic stage I, II) and
'Advanced stage CHC' (sonographic stage III, IV, V). Student's t-test was applied to compare the means of the
values for different sonographic parameters in the two groups.
Results: The study included 178 patients with male to female ratio of 1.86:1. Mean age was 47.5 ± 12.5 years.
Prevalence of sonographic stages I, II, III, IV, Va and Vb in study population was 68% (n=121), 12% (n=21), 9%
(n=16), 6% (n=11), 3% (n=5) and 2% (n=4) respectively. 'Early stage CHC' and 'advanced stage CHC' showed
statistically significant (p-value
Cirrhosis, End stage liver disease, Hepatitis C, Hepatitis C antibodies, Ultrasonongraphy