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Original Research

IJCRR. 2012; 4(19): 128-132


STUDY OF C - REACTIVE PROTEIN, MALONDIALDEHYDE AND URIC ACID LEVELS IN PREDICTING OUTCOME IN ACUTE MYOCARDIAL INFARCTION

Mriganka Baruah, Chandan Nath, Sapna Goyal, Bobby Das, Runi Devi.

Abstract
Acute Myocardial Infarction (AMI) is an important health problem with poor outcome despite impressive advancement in diagnosis and management. Objective: The purpose of this study is to investigate the role of C-reactive protein (CRP), Malondialdehyde (MDA) and serum Uric Acid as a predictor of outcome in Acute Myocardial Infarction (AMI). Materials & Method: A study was conducted in 72 subjects; 42 patients with AMI (35 years to 81 years), of which 6 patients expired during the study (4 Males, 2 Females) and 30 age and sex matched healthy control. These subjects are divided into among 3 groups, Group I- 6 AMI patients who expired after 7th day, Group II -36 patients with AMI; and Group III- 30 control group. Serum CRP, Uric acid & MDA readings were taken on day 1, 3 & 7 from the onset of symptoms. Result: Group I and II readings are found statistically significant (p

Key words: Death, Acute Myocardial Infarction (AMI), C-reactive protein (CRP), Malondialdehyde (MDA), Uric acid, Lipid Peroxidation, Oxidative Stress.



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