Objective: To compare medical versus surgical treatment of nasal polyps in terms of frequency of success and
Study Design: Randomized controlled trial.
Place and Duration of Study: This study was conducted at the department of ear nose throat (ENT), Combined
Military Hospital (CMH) Peshawar over 2 years’ period, from Jan 2000 to Dec 2002.
Material and Methods: During this period, 80 patients were diagnosed of nasal polyps. These patients were
randomly divided into two treatment groups. Patients in group-A received medical treatment in the form of
intra-nasal steroids while patients in group-B received surgical treatment depending upon the extent of disease.
Outcome variables were frequency of successful resolution of nasal polyps after 1 month of treatment and
frequency of recurrence upon 1 year follow-up.
Results: The age of the patients ranged from 15 years to 40 years with a mean of 26.13 ± 2.5 years. There were 49
(61.25%) male and 31 (38.75%) female patients in the study group giving a male to female ratio of 1.6:1. There was
no significant difference between the two study groups in terms of gender (p=0.818) distribution. Bilateral
intranasal polypectomy was the most frequently performed procedure (70.0%) followed by intranasal
ethmoidectomy (12.5%), external ethmoidectomy (10.0%) and functional endoscopic sinus surgery (7.5%). The
frequency of successful treatment was significantly higher with surgery (100% vs. 52.50%; p
Intra-nasal steroids, Nasal Polyp, Recurrence, Surgery, Successful treatment.