Background: Nearly, every day young people die from injuries, especially from motor vehicle injuries, poisoning, violence, falls, and burns.
Objective: The present study aimed to address the major causes of death and its burden in Africa.
Materials and Methods: This population-based cross-sectional study, which a dataset was created by compiling from the World Health Organization for 2010–2015.
Results: This study indicates the correlation was considered to be higher in “drowning” for young people (r = 0.926) than the old population (r = 0.589). In addition, this study reported that the leading cause of death in Africa is due to road injuries. Correlation coefficient shows that young people the greater the chance to lose life due to road injury (r = 0.753) and is lower compared to the old people (r = 0.476). In addition, young people lose their lives through poisoning injuries; the correlation was slightly higher (r = 8.25) and lower for old people (r = 0.650).
Conclusion: Young people are among the most vulnerable when it comes to injuries. The international organizations must work with partners in Africa to raise the awareness on road traffic injuries, drowning, poisoning, and falls.
Death; Injury; Reproductive Age Group; Africa