Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Article

PAFMJ. 2018; 68(2): 265-268


IN VITRO SUSCEPTIBILITY OF MRSA CLINICAL ISOLATES TO CEFTAROLINE

Muhammad Aurangzeb, Raja Kamran Afzal, Muhammad Abid, Aamir Hussain, Fauzia Aitazaz, Rozina Khaliq.

Abstract
Objective: To determine the in vitro susceptibility of MRSA clinical isolates to ceftaroline, using interpretation of
zones of inhibition by disk diffusion method.
Study Design: Descriptive cross sectional.
Place and Duration of Study: The study was carried out at the Department of Microbiology, Combined Military
Hospital Peshawar, from Jan to Dec 2014.
Material and Methods: To carry out this descriptive cross sectional study, clinical specimens were obtained from
indoor and outdoor patients of Combined Military Hospital Peshawar. All the isolates of MRSA cultured with
CLSI guidelines and identified with standard microbiological procedures, from clinical specimens of pus, body
fluid, urine, tissue and blood were included in the study. The antimicrobial susceptibility pattern of ceftaroline
was determined according to CLSI guidelines. The data was analyzed in SPSS (version 19) software.
Results: Out of a total 190 MRSA isolates, 183 (96.3%) were susceptible to ceftaroline in vitro, whereas 5 (2.6%)
were resistant and 2 (1.1%) were intermediate in their response to ceftaroline.
Conclusion: Ceftaroline can be used effectively against infections caused by MRSA as it has shown very high in
vitro activity against MRSA strains of clinical origin.

Key words: Antimicrobial susceptibility, Ceftaroline, MRSA.



Share this Article


Advertisement
Journal of Interdisciplinary Histopathology

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons