Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research

Natl J Med Res. 2012; 2(4): 423-426


Evaluation of Serum Homocysteine as an Independent Risk Factor for Myocardial Infarction in Young Patients

Asutosh P Chauhan, Piyush B Tailor, Rachit Joshi, Prakash Bhabhor.

Abstract
that damages the arterial linings, interfering with the clotting factors and oxidation of LDL. Some 10% to 20% of cases of Coronary heart disease have been linked to elevated level of serum Homocysteine.
Objective: This case control study was designed to study the Homocysteine levels in young patients with MI & to carry out statistical analysis to evaluate Homocysteine as an independent risk factor for MI.
Methods: The mean serum Homocysteine in patients of MI and control was calculated and its association with Total cholesterol, LDL cholesterol and HDL cholesterol.
Results: The mean serum Homocysteine in case and control was 29.77 µmol / L and 11 µmol / L respectively with S.D of 6.97 µmol / L and 1.96 µmol / L respectively with a significant p value of 0.0001. The difference in Homocysteine levels observed between patients with LDL-C ā‰„ 100 mg% and those with LDL-C < 100 mg% was not significant. The difference in Homocysteine levels observed between patients with HDL-C ā‰„ 40 mg% and those with HDL-C < 40 mg% was not significant. The difference in Homocysteine levels observed between patients with S. Cholesterol ā‰„ 200 mg% and those with S. Cholesterol < 200 mg% was significant ( P value = 0.0001).
Conclusion: From the above findings, in this study the low levels of LDL-C and high levels of HDL-C did not protect the patients against the Homocysteine induced coronary artery disease. Also it shows that in patients who did not have high levels of total cholesterol, the higher levels of Serum Homocysteine triggered the coronary artery disease.

Key words: Homocysteine (HCY), MI, LDL, HDL.



Share this Article


Advertisement
Journal of Environmental and Occupational Science

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright © ScopeMed® Information Services.
Scopemed Buttons