Abstract
The role of psychosocial factors in patients' clinical presentations are being commonly evaluated and managed during physical therapy along a comprehensive biopsychosocial approach to care. Placebo is a positive therapeutic experience secondary to perceived beneficial outcome whereas nocebo is otherwise. The objective of this editorial was to provide an insight into mechanisms of placebo and nocebo, with implications for use in physical therapy.

Key words: biopsychosocial rehabilitation, placebo, nocebo, therapy responses, patient expectation.