Journal Management System
 
Home  |   Add your Journal  |   Features  |   Journal List
Author Login | Reviewer Login | Editor Login
Search  

National Journal of Physiology, Pharmacy and Pharmacology
Periodical of Mrs Dipika Charan
Journal Home Page
ISSN: 2320-4672 (Print)
ISSN: 2231-3206 (Online)
Language: [ English ]  
News / Announcements

  » Volume 4, Issue 2
      pp. 99-178
  » Volume 4, Issue 1
      pp. 1-98

 

Open Access

Original Research



Are there any genotoxic effects of laser epilation applications on human? An observational study

Zeynep Ocak, Tülay Özlü, Sener Tasdemir, Handan Bilen, Ertuğrul Mevlüt Kocaman.

Abstract
Background: Laser epilation is a method of removal of unwanted hair from the body and its use for this cosmetic purpose is gaining increasing popularity. Sister chromatid exchange (SCE) is a critical method for determining genotoxicity caused by several mutagens and carcinogens under in vivo and in vitro conditions.

Aims & Objective: In this study, we aimed to determine whether removal of unwanted hair by laser epilation causes genotoxicity in women undergoing this procedure.

Materials and Methods: 40 voluntary women who admitted to the dermatology clinics for the removal of unwanted hair by laser epilation were included. Skin types of all patients were classified according to Fitzpatrick Scale. Laser epilation was applied by Alexandrite (Light Age Epicare Duo) at a 755 nm wavelength laser. The possible genotoxic effects in women who had laser epilation to the whole leg (upper and lower leg) and face was investigated by the SCE method.

Results: The blood samples that were drawn before and 24 hours after the laser application showed no significant differences between the SCE frequencies (p>0.05).

Conclusion: We could not find any significant genotoxic effect of laser epilation in women undergoing this procedure. As far as we know, this is the first study that investigates the relationship between laser applications and genotoxic effects.

Key words: Laser; Hair Removal; Sister Chromatid Exchange



REFERENCES
1. Zandi S, Lui H. Long-term removal of unwanted hair using light. Dermatol Clin. 2013;1:179-91.
 
2. Anderson RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science. 1983;220:524-7. http://dx.doi.org/10.1126/science.6836297
 
3. Mortelmans K, Zeiger E. The Ames Salmonella/ microsome mutagenicity assay. Mutat Res. 2000;455:29-60 http://dx.doi.org/10.1016/S0027-5107(00)00064-6
 
4. Wilson DM, Thompson LH. Molecular mechanisms of sister-chromatid exchange. Mutat Res. 2007;616:11-23. http://dx.doi.org/10.1016/j.mrfmmm.2006.11.017
 
5. Sachdeva S. Fitzpatrick skin typing: Applications in dermatology Indian J Dermatol Venereol Leprol. 2009;75:1 http://dx.doi.org/10.4103/0378-6323.45238
 
6. Narurkar VA. Lasers, light sources, and radiofrequency devices for skin rejuvenation. Semin Cutan Med Surg. 2006;25:145-50 http://dx.doi.org/10.1016/j.sder.2006.06.007
 
7. Tanzi EL, Lupton JR, Alster TS. Lasers in dermatology: four decades of progress. J Am Acad Dermatol. 2003;49:1-31; quiz 31-4 http://dx.doi.org/10.1067/mjd.2003.582
 
8. Uyar B, Saklamaz A. Effects of the 755-nm Alexandrite laser on fine dark facial hair: Review of 90 cases. J Dermatol. 2012;39:430-2 http://dx.doi.org/10.1111/j.1346-8138.2011.01480.x
 
9. Solarczyk KJ, Zar˛ebski M, Dobrucki JW. Inducing local DNA damage by visible light to study chromatin repair. DNA Repair (Amst). 2012;11(12):996-1002. http://dx.doi.org/10.1016/j.dnarep.2012.09.008
 
10. Kong X, Mohanty SK, Stephens J, Heale JT, Gomez-Godinez V, Shi LZ, Kim J, Yokomori K, Berns MW. Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells. Nucleic Acids Res. 2009;37-68
 
11. Karadag A, Yesilyurt A, Unal S, Keskin I, Demirin H, Uras N, et al. A chromosomal-effect study of intensive phototherapy versus conventional phototherapy in newborns with jaundice. Mutat Res. 2009;676:17-20 http://dx.doi.org/10.1016/j.mrgentox.2009.03.008
 
12. Dang Y, Liu B, Liu L, Ye X, Bi X, Zhang Y, et al. The 800-nm diode laser irradiation induces skin collagen synthesis by stimulating TGF-β/Smad signaling pathway. Lasers Med Sci. 2011;26:837-43 http://dx.doi.org/10.1007/s10103-011-0985-z
 

How to Cite this Article
Pubmed Style

Ocak Z, Özlü T, Tasdemir S, Bilen H, Kocaman EM. Are there any genotoxic effects of laser epilation applications on human? An observational study. Natl J Physiol Pharm Pharmacol. 2014; 4(1): 43-46. doi:10.5455/njppp.2014.4.120720131



Web Style

Ocak Z, Özlü T, Tasdemir S, Bilen H, Kocaman EM. Are there any genotoxic effects of laser epilation applications on human? An observational study. www.scopemed.org/?mno=39568 [Access: October 23, 2014]. doi:10.5455/njppp.2014.4.120720131



AMA (American Medical Association) Style

Ocak Z, Özlü T, Tasdemir S, Bilen H, Kocaman EM. Are there any genotoxic effects of laser epilation applications on human? An observational study. Natl J Physiol Pharm Pharmacol. 2014; 4(1): 43-46. doi:10.5455/njppp.2014.4.120720131



Vancouver/ICMJE Style

Ocak Z, Özlü T, Tasdemir S, Bilen H, Kocaman EM. Are there any genotoxic effects of laser epilation applications on human? An observational study. Natl J Physiol Pharm Pharmacol. (2014), [cited October 23, 2014]; 4(1): 43-46. doi:10.5455/njppp.2014.4.120720131



Harvard Style

Ocak, Z., Özlü, T., Tasdemir, S., Bilen, H. & Kocaman, E. M. (2014) Are there any genotoxic effects of laser epilation applications on human? An observational study. Natl J Physiol Pharm Pharmacol, 4 (1), 43-46. doi:10.5455/njppp.2014.4.120720131



Turabian Style

Ocak, Zeynep, Tülay Özlü, Sener Tasdemir, Handan Bilen, and Ertuğrul Mevlüt Kocaman. 2014. Are there any genotoxic effects of laser epilation applications on human? An observational study. National Journal of Physiology, Pharmacy and Pharmacology, 4 (1), 43-46. doi:10.5455/njppp.2014.4.120720131



Chicago Style

Ocak, Zeynep, Tülay Özlü, Sener Tasdemir, Handan Bilen, and Ertuğrul Mevlüt Kocaman. "Are there any genotoxic effects of laser epilation applications on human? An observational study." National Journal of Physiology, Pharmacy and Pharmacology 4 (2014), 43-46. doi:10.5455/njppp.2014.4.120720131



MLA (The Modern Language Association) Style

Ocak, Zeynep, Tülay Özlü, Sener Tasdemir, Handan Bilen, and Ertuğrul Mevlüt Kocaman. "Are there any genotoxic effects of laser epilation applications on human? An observational study." National Journal of Physiology, Pharmacy and Pharmacology 4.1 (2014), 43-46. Print. doi:10.5455/njppp.2014.4.120720131



APA (American Psychological Association) Style

Ocak, Z., Özlü, T., Tasdemir, S., Bilen, H. & Kocaman, E. M. (2014) Are there any genotoxic effects of laser epilation applications on human? An observational study. National Journal of Physiology, Pharmacy and Pharmacology, 4 (1), 43-46. doi:10.5455/njppp.2014.4.120720131



Submit your manuscript
Register
Abstracting & Indexing
Instructions for Authors
Editorial Board
Aims & Scope
About this Journal
Sign up for TOC

ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Export to
Export to
Related Records
 Articles by Zeynep Ocak
Articles by Tülay Özlü
Articles by Sener Tasdemir
Articles by Handan Bilen
Articles by Ertuğrul Mevlüt Kocaman
on IndexScholar Fulltext
on Google
on Google Scholar
Article Statistics
 Viewed: 701
Downloaded: 282
Cited: 0

News / Announcements

  • NJPPP Indexed in SCOPUS ['May 19, 2014']

  • Journal is Indexed in EMBASE ['Feb 15, 2013']

  • Hard copy of journal ['Feb 11, 2013']





  •  




    » For Authors




    Become Reviewer


    » Login Area






    Follow ScopeMed on Twitter

    ScopeMed Home
    Job Opportunities/Service Offers
    About ScopeMed
    Terms & Conditions
    Privacy Policy
    Contact Us

    The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
    ScopeMed is a Service of SAGEYA Publishing for Scientific Publications. Copyright © ScopeMed® International Medical Journal Management and Indexing System.