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Medical Archives
Periodical of AVICENA, d.o.o., Sarajevo
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ISSN: 0350-199X (Print)
ISSN: 1986-5961 (Online)
Language: [ English ]  
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Open Access

Original Research



Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients

Diana Naço, Drini Dobi, Ilirijana Zekja, Silvana Mijo, Mira Kapisyzi, Jera Kruja.

Abstract
Aim: To evaluate the usefulness of MMSE score in vascular dementia and the influence of different factors on the MMSE score. Subject and methods: We studied 78 stroke patients followed up at the neurology unit, Specialistic Polyclinic 2, Tirana. A neurological visit is done and the MMSE score is calculated for each of them. We noted the stroke form (ischemic, hemorrhagic), patient’s age, education, time from stroke onset, accompanying neurological disorders (parkinsonism, epilepsy), risk factors (arterial hypertension, cardiac diseases, diabetes mellitus, smoking, carotid stenosis). The imaging (CT and/or MRI) of the brain is requested. Independent Samples Test, t-test for Equality of Means, 2 – tailed, is applied for the statistical evaluation. Results: The mean age of the patients in the study is 70.31 years old. There are 37 females (47.43%) and 41 males (52.56%). 12 (15.38%) patients had hemorrhagic and 66 (84.61%) ischemic stroke. The mean time from stroke onset is 4.55 years. 15 (19.2%) patients have parkinsonism, 1 other extra pyramidal disorder, 3 (3.8%) secondary generalized epilepsy. The mean MMSE score for all patients is 23.48. The multi ischemic cerebral lesions were present in the imaging of 12 (15.38%) patients. The generalized cortical atrophy is found in 25 (32%) patients and the temporal atrophy in 14 (17.94%) patients. We analyzed the data of 37 patients [16 (43.24%) females and 21 (56.75%) males], with MMSE score ≤23. The mean age is 75.39 years old. 6 (16.21%) patients are diagnosed with hemorrhagic stroke. 3(8.1%) patients have secondary generalized epilepsy, 9 (24.32%) are suffering of parkinsonism and the mean time from stroke onset is 4.31 years. The imaging study revealed multi ischemic cerebral lesions in 9 (24.3%) patients. We found accompanying temporal atrophy in 10 (27%) patients, frontal atrophy in 2 (5.4%) patients, and generalized cortical atrophy in 17 (45.9%) patients. Conclusion: Dementia after stroke is frequent. The MMSE is still a useful scale to evaluate the VaD and is related to age, gender, education, stroke age, cardiovascular risk factors, stroke type and localization, other neurological disorders as epilepsy and parkinsonism.

Key words: stroke, Mini-Mental State (MMSE), neurological disorders, vascular dementia (VaD).



REFERENCES
1. Ott A, Breteler MM, Van Harskamp F, Claus JJ, Van Der Cammen TJ, Grobbee DE, Hofman A. Prevalence of Alzheimer's disease and vascular dementia: association with education. The Rotterdam study. BMJ. 1995; 310: 970-973. http://dx.doi.org/10.1136/bmj.310.6985.970   [Pubmed]          [PMC Free Fulltext]    
 
2. Hachinski VC, Lassen NA, Marshall J. Multi-infarct dementia. A cause of mental deterioration in the elderly. Lancet. 1974 Jul 27; 2(7874): 207-210. http://dx.doi.org/10.1016/S0140-6736(74)91496-2
 
3. Bowler JV, Hachinski V. Vascular cognitive impairment: a new approach to vascular dementia. Baillieres Clin Neurol. 1995 Aug; 4(2): 357-376.   [Pubmed]       
 
4. Korczyn AD. The complex nosological concept of vascular dementia. Journal of the Neurological Sciences. 2002; 203-204.
 
5. Pendlebury ST, Rothwell PM. Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis. Lancet Neurol. 2009; 8: 1006-1018. http://dx.doi.org/10.1016/S1474-4422(09)70236-4
 
6. Kase CS, Wolf PA, Kelly-Hayes M. et al. Intellectual Decline After Stroke. The Framingham Study Stroke. 1998; 29: 805-812. http://dx.doi.org/10.1161/01.STR.29.4.805
 
7. Folstein, MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12: 189-198. http://dx.doi.org/10.1016/0022-3956(75)90026-6
 
8. Palmqvist S. Validation of brief cognitive tests. Thesis 2011. Lund University. Sweden.
 
9. Jefferson AL, Cosentino SA, Ball SK, Bogdanoff B, Leopold N, Kaplan E, Libon D J. Errors produced on the mini-mental state examination and neuropsychological test performance in Alzheimer's disease, ischemic vascular dementia, and Parkinson's disease. J Neuropsychiatry Clin Neurosci. 2002; 14: 311-320. http://dx.doi.org/10.1176/appi.neuropsych.14.3.311   [Pubmed]       
 
10. Tang WK, Chan S, Chiu H. et al. Frequency and determi­tants poststroke of dementia in Chinese. Stroke. 2004; 35: 930-993. http://dx.doi.org/10.1161/01.STR.0000119752.74880.5B   [Pubmed]       
 
11. Ivan CS, Seshadri S, Beiser A, et al. Dementia after stro­ke. The Framingham Study. Stroke. 2004; 35: 1264-1269. http://dx.doi.org/10.1161/01.STR.0000127810.92616.78   [Pubmed]       
 
12. Hebert R, Lindsay J, Verrault R, et al. Vascular dementia: incidence and risk factors in the Canadian Study of Health and Aging. Stroke. 2000; 31(7): 1487-1493. http://dx.doi.org/10.1161/01.STR.31.7.1487   [Pubmed]       
 
13. Račić D, Slankamenac P, Vujković Z. et al. Vascular dementia: clinical and neuroradiological correlation Med Pregl. 2011; LXIV (3-4): 152-156.
 
14. Sahathevan R, Brodtmann A, Donnan GA. Dementia, stroke, and vascular risk factors; a review. Int J Stroke. 2012 Jan; 7(1): 61-73. doi: 10.1111/j.1747-4949.2011.00731.x http://dx.doi.org/10.1111/j.1747-4949.2011.00731.x
 
15. Waldstein SR, Giggey PP, Thayer JF, Zonderman AB. Nonlinear relations of blood pressure to cognitive function. Hypertension. 2005; 45: 374-379. http://dx.doi.org/10.1161/01.HYP.0000156744.44218.74   [Pubmed]       
 
16. Cordonnier C, Hénon H, Derambure P, Pasquier F, Leys D. Early epileptic seizures after stroke are associated with increased risk of new-onset dementia. J Neurol Neurosurg Psychiatry. 2007 May; 78(5): 514-516. http://dx.doi.org/10.1136/jnnp.2006.105080   [Pubmed]          [PMC Free Fulltext]    
 
17. Gemmell E, Bosomworth H, Allan L, Hall R, Khundakar A, Oakley AE, Deramecourt V, Polvikoski TM, Lehéricy S, Delmaire C, Galanaud D, Dormont D. Neuroimaging in dementia.Presse Med. 2007 Oct; 36(10 Pt 2): 1453-1463.
 
18. Tatemichi TK, Foulkes MA, Mohr JP, et al. Dementia in stroke survivors in the Stroke Data Bank cohort: prevalence, in­cidence, risk factors and computed tomographic findings. Stroke. 1990; 21: 858-866. http://dx.doi.org/10.1161/01.STR.21.6.858   [Pubmed]       
 

How to Cite this Article
Pubmed Style

Naço D, Dobi D, Zekja I, Mijo S, Kapisyzi M, Kruja J. Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients . Med Arh. 2013; 67(3): 171-173. doi:10.5455/medarh.2013.67.171-173



Web Style

Naço D, Dobi D, Zekja I, Mijo S, Kapisyzi M, Kruja J. Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients . www.scopemed.org/?mno=39606 [Access: October 02, 2014]. doi:10.5455/medarh.2013.67.171-173



AMA (American Medical Association) Style

Naço D, Dobi D, Zekja I, Mijo S, Kapisyzi M, Kruja J. Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients . Med Arh. 2013; 67(3): 171-173. doi:10.5455/medarh.2013.67.171-173



Vancouver/ICMJE Style

Naço D, Dobi D, Zekja I, Mijo S, Kapisyzi M, Kruja J. Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients . Med Arh. (2013), [cited October 02, 2014]; 67(3): 171-173. doi:10.5455/medarh.2013.67.171-173



Harvard Style

Naço, D., Dobi, D., Zekja, I., Mijo, S., Kapisyzi, M. & Kruja, J. (2013) Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients . Med Arh, 67 (3), 171-173. doi:10.5455/medarh.2013.67.171-173



Turabian Style

Naço, Diana, Drini Dobi, Ilirijana Zekja, Silvana Mijo, Mira Kapisyzi, and Jera Kruja. 2013. Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients . Medical Archives, 67 (3), 171-173. doi:10.5455/medarh.2013.67.171-173



Chicago Style

Naço, Diana, Drini Dobi, Ilirijana Zekja, Silvana Mijo, Mira Kapisyzi, and Jera Kruja. "Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients ." Medical Archives 67 (2013), 171-173. doi:10.5455/medarh.2013.67.171-173



MLA (The Modern Language Association) Style

Naço, Diana, Drini Dobi, Ilirijana Zekja, Silvana Mijo, Mira Kapisyzi, and Jera Kruja. "Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients ." Medical Archives 67.3 (2013), 171-173. Print. doi:10.5455/medarh.2013.67.171-173



APA (American Psychological Association) Style

Naço, D., Dobi, D., Zekja, I., Mijo, S., Kapisyzi, M. & Kruja, J. (2013) Factors Influencing Mini-mental State (MMSE) Score in Stroke Patients . Medical Archives, 67 (3), 171-173. doi:10.5455/medarh.2013.67.171-173



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