Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

6

IJAVMS. 2010; 4(3): 88-95


Investigation of Hypoglycemic Effect of Ceiba Pentandra Root Bark Extract in Normal and Alloxan Induced Diabetic Albino Rats

Saif-ur-Rehman, Saghir A. Jafri, Ishtiaq Ahmed, Abdul Shakoor, Hafiz M.N. Iqbal, Bilal Munir Ahmad, Imran Tipu.

Abstract
The present work was designed to investigate the hypoglycemic effect of Ceiba pentandra root bark extract in normal and alloxan induced diabetic rats. To investigate the effect of Ceiba pentandra 40 albino rats were included in this study divided into four groups of ten rats in each group. Group A and B rats were normal while diabetes was induced in group C and D rats by intraperitoneal injection of alloxan dissolved in 1mL of distilled water at a dose of 125mg/kg body weight. The Ceiba pentandra root bark extract was given orally at a dose of 150mg/kg of body weight. Data was taken after seven days of administration of alloxan. After the induction of diabetes the group B and D rats were treated with Ceiba pentandra root bark extract at a dose of 150mg/kg of body weight. Group A and C rats were not treated with Ceiba pentandra root bark extract. The blood samples from all the rats were collected from coccygial vein on 1st day, then on 21st and 42nd day respectively. All the samples were analyzed for blood glucose level by using enzymatic kits. The blood glucose level of treated groups of rats showed significant reduction after 7 weeks of treatment with Ceiba pentandra root bark extract. By statistical analysis of results it was found that Ceiba pentandra root bark extract has hypoglycemic effect in normal and alloxan induced diabetic rats.

Key words: Albino rats, alloxan, Ceiba pentandra, hypoglycemic effect



Share this Article


Advertisement
American Journal of Preventive Medicine and Public Health

SUBMIT YOUR ARTICLE NOW




ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Article Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Suggest a Journal
Publisher Login
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons