Home|Journals Follow on Twitter| Subscribe to List

Directory for Medical Articles
 

Open Access

Original Research



Study of cord blood ischemia modified albumin levels in the evaluation of birth asphyxia

Soumyadeep Biswas, Pinaki Sarkar, Indranil Chakraborty, Sibarjun Ghosh, Ramesh Chandra Halder.

Abstract
Objective: In birth asphyxia several new biochemical markers are now investigated. Recent studies indicate the role of ischemia modified albumin, a biomarker determined by assay of cobalt binding activity of albumin. The aim of this study was to evaluate the role of ischemia modified albumin in birth asphyxia.
Materials and methods: 40 newborns with APGAR score less than 7 were selected at random. Low birth weight, premature and newborns from caesarian section were excluded. Ischemia modified albumin was determined by assay of its cobalt binding activity with spectrophotometer. Mothers with history of preeclampsia and preexisting renal disease were kept out of the study. Similar observations were made in 40 normal newborns taken as control.
Results: Cord blood ischemia modified albumin levels were higher in asphyxiated newborns compared to controls (55.71.7 U/ml compared to 32.441.15 U/ml). Raised levels of IMA in those subjects had shown very significant correlations with the APGAR scores of 5 minutes, a finding also observed in case of controls.
Conclusion: The findings of the current study indicate that ischemia modified albumin can be a very useful marker in evaluation of birth asphyxia.

Key words: Birth asphyxia, 5 minute APGAR score, Ischemia modified albumin, Albumin cobalt binding assay



Share this Article


Advertisement
Journal of Contemporary Medical Education

SUBMIT YOUR ARTICLE NOW


ScopeMed.com
ScopeMed Home
Follow ScopeMed on Twitter
BiblioCAM
Author Tools
eJPort Journal Hosting
About ScopeMed
License Information
Terms & Conditions
Privacy Policy
Contact Us

The articles in Scopemed are open access articles licensed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
ScopeMed is a Database Service for Scientific Publications. Copyright ScopeMed Information Services.
Scopemed Buttons