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Case Report

Gulhane Med J. 2006; 48(2): 112-114


Successful treatment of lichen amyloidosis with cryosurgery

Engin Sezer1, A.Hakan Erbil2, R.Doğan Köseoğlu3, Nurper Filiz3, Zafer Kurumlu2.

Abstract
Lichen amyloidosis is a rare, chronic pruritic disorder characterized by amyloid deposition in the skin without evidence of visceral involvement. Clinically, lichen amyloidosis demonstrates discrete, intensely pruritic, hyperkeratotic papules that may coalesce into plaques, mainly located on the legs. Different treatment modalities including topical and intralesional corticosteroids, topical dimethyl sulfoxide, ultraviolet B, oral psoralen plus ultraviolet A, retinoids and dermabrasion have been described, but the results are generally disappointing. There are paucity of reports of liquid nitrogen cryosurgery as a treatment option in the management of lichen amyloidosis in the literature. In this article, we report a case of lichen amyloidosis, with pruritic hyperkeratotic papules on the left shin of 7 years' duration, successfully treated with cryosurgery.

Key words: Cryosurgery, lichen amyloidosis, treatment



Liken amiloidoz'un kriyocerrahiyle başarılı tedavisi

Özet
Liken amiloidoz, iç organ tutulumu olmaksızın deride amiloid birikimi ile seyreden, ender, kronik ve kaşıntılı bir cilt hastalığıdır. Liken amiloidoz, çoğunlukla bacaklarda yerleşim gösteren kaşıntılı, plak oluşumuna neden olabilen ayrı yerleşimli hiperkeratotik papüllerle klinik seyir gösterir. Tedavi seçeneği olarak topikal ve intralezyoner kortikosteroid, topikal dimetilsülfoksit, ultraviyole B, oral psoralen ve ultraviyole A, retinoik asidler ve dermabrazyon yer almakla birlikte, sonuçlar genellikle yüz güldürücü değildir. Literatürde Liken amiloidoz tedavisinde kriyoterapinin etkinliği ile ilgili çok az sayıda çalışma bulunmaktadır. Bu makalede, 7 yıldır devam eden, sol bacakta kaşıntılı hiperkeratotik papüllerin gözlendiği ve kriyoterapi ile başarıyla tedavi edilen bir liken amiloidoz olgumuzu sunuyoruz.

Anahtar Kelimeler: Kriyoterapi, liken amiloidoz, tedavi



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