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TSK Koruyucu Hekimlik Bülteni
TAF Preventive Medicine Bulletin
Periodical of Gulhane Medical Faculty Dpt. of Public Health
Journal Home Page
ISSN: 1303-734X (Print)
Language: [ Turkish ]   [ English ]  

  » Volume 12, Issue 6
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  » Volume 12, Issue 1
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Open Access

Editorial



Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster

Ahmet Korkmaz, Dun-Xian Tan, Russel J Reiter.

Cited by (2)

Abstract
In spite of its widespread use and the well known potential hazards associated with exposure to ionizing radiation, countries are poorly ill-equipped to protect their citizens in case of a fallout as seen in northeastern region of Japan.
In case of nuclear fallout, there is no practical way to save people from the hazardous effects of ionizing radiation. Health authorities may provide potassium iodide for people to prevent thyroid cancer. Another preventive attempt would be using amifostine, a well known agent with radioprotective features.
Melatonin (N-acetyl-5-methoxytryptamine) is a pineal product which is also known to have robust radioprotective features. Both human and experimental animal studies have clearly shown that it is a unique antioxidant and a DNA and chromosome protector against a variety of harmful agents including ionizing radiation.

Key words: melatonin, ionizing radiation, protection



Melatonin; Japon Nükleer Felaketine Karşı Etkin Bir Radyasyondan Koruyucu Ajan

Özet
Yaygın kullanımına ve iyonizan radyasyona maruziyetin iyi bilinen potansiyel tehlikelerine rağmen ülkeler, Japonya’nın kuzeydoğusunda görüldüğü gibi nükleer patlamaya bağlı salınım durumunda kendi vatandaşlarını korumak için çaresiz bir şekilde kötü donanıma sahiptirler. Nükleer patlamaya bağlı salınım durumunda insanları iyonizan radyasyonun tehlikeli etkilerinden koruyacak pratik bir yol yoktur. Sağlık otoriteleri tiroid kanserlerini önlemek için insanlara potasyum iyodür dağıtabilirler. Bir diğer koruyucu girişim radyoprotektif özellikleri ile tanınan amifostin kullanımı olabilir. Melatonin (N-asetil-5-metoksi triptamin) pineal bezden salınan, güçlü radyoprotektif özellikleri bilinen bir üründür. Melatoninin benzersiz bir antioksidan olduğu ve iyonizan radyasyonu da içeren bir çok tehlikeli ajana karşı DNA ve kromozom koruyucusu olduğu hem insan hem hayvan deneylerinde açıkça gösterilmiştir.

Anahtar Kelimeler: melatonin, iyonize radyasyon, korunma



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This Article Cited By the following articles

The Mechanisms of Positive Effects of Melatonin in Dyslipidemia: A Systematic Review of Animal and Human Studies
International J. of Pharmacology 2012; 8(6): 496.

1
 
Fukushima Daiichi Nuclear Power Plant accident: facts, environmental contamination, possible biological effects, and countermeasures
Journal of Clinical Biochemistry and Nutrition 2011; 50(1): 2-8.

2
 

How to Cite this Article
Pubmed Style

Korkmaz A, Tan D, Reiter RJ. Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster. TAF Prev Med Bull. 2011; 10(2): 127-129. doi:10.5455/pmb.20110320020401



Web Style

Korkmaz A, Tan D, Reiter RJ. Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster. www.scopemed.org/?mno=6291 [Access: December 02, 2016]. doi:10.5455/pmb.20110320020401



AMA (American Medical Association) Style

Korkmaz A, Tan D, Reiter RJ. Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster. TAF Prev Med Bull. 2011; 10(2): 127-129. doi:10.5455/pmb.20110320020401



Vancouver/ICMJE Style

Korkmaz A, Tan D, Reiter RJ. Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster. TAF Prev Med Bull. (2011), [cited December 02, 2016]; 10(2): 127-129. doi:10.5455/pmb.20110320020401



Harvard Style

Korkmaz, A., Tan, D. & Reiter, R. J. (2011) Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster. TAF Prev Med Bull, 10 (2), 127-129. doi:10.5455/pmb.20110320020401



Turabian Style

Korkmaz, Ahmet, Dun-Xian Tan, and Russel J Reiter. 2011. Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster. TAF Preventive Medicine Bulletin, 10 (2), 127-129. doi:10.5455/pmb.20110320020401



Chicago Style

Korkmaz, Ahmet, Dun-Xian Tan, and Russel J Reiter. "Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster." TAF Preventive Medicine Bulletin 10 (2011), 127-129. doi:10.5455/pmb.20110320020401



MLA (The Modern Language Association) Style

Korkmaz, Ahmet, Dun-Xian Tan, and Russel J Reiter. "Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster." TAF Preventive Medicine Bulletin 10.2 (2011), 127-129. Print. doi:10.5455/pmb.20110320020401



APA (American Psychological Association) Style

Korkmaz, A., Tan, D. & Reiter, R. J. (2011) Melatonin; an Established Radioprotective Agent Against Japan’s Nuclear Disaster. TAF Preventive Medicine Bulletin, 10 (2), 127-129. doi:10.5455/pmb.20110320020401



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