Objective: To analyze the precipitating factors of hepatic encephalopathy
Methods: Two hundred admitted patients with liver cirrhosis with HE from
1st January 2006 to 30th September 2006 were included in the study. Grades
of HE and Childâ€™s Pugh classification was also determined.
Results: Out of 200 patients, 106 (53%) were male and 94 (47%) female.
Amongst the precipitating factors, 30% had constipation, 29% upper
gastrointestinal bleed (GIB), 8% spontaneous bacterial peritonitis (SBP),
19.5% urinary tract infection (UTI), 2.5% lower respiratory tract infection
and 3% had diarrhea. There was hyponatremia in 1.5% and hypokalemia in
4.5% patients. High protein diet in 0.5% and bromazepam intake in 1%
were presumed precipitating factors and 0.5% had antituberculous therapy
induced liver injury.
Conclusion: Constipation, gastrointestinal bleeding and infections were the
most common precipitating factors of HE in our patients. (Rawal Med J
Hepatic Encephalopathy, liver cirrhosis, precipitating factors,