ScopeMed - RSShttp://www.scopemed.orgScopeMed RSSen-us Copyright © 2011 ScopeMed All rights reserved. ScopeMedhttp://www.scopemed.org/img/logo-scopemed-ttk.gifhttp://www.scopemed.org 2014-11-23T02-41-54Z Multi lobulated large ivory osteoma of ascending ramus: A case report http://www.scopemed.org/?mno=159324 2014-11-23T02-41-54Z
Source: Journal of Clinical & Experimental Research
A.N.C. John.
Osteoma is a benign often asymptomatic neoplasm. Peripheral osteomas, the involvement of mandible and maxilla are very rare. In this case report, the growth was present on the mandible with lobulated on the lateral aspect of the ascending ramus with involvement of posterior and medial aspect of ramus at the level of lingua with an overall size of 5 cm.
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Sun, 23 Nov 2014 01:53:42 GMT -08:00 http://www.scopemed.org/?mno=159324
Antimicrobial drug utilization pattern in neonatal sepsis in a tertiary care hospital http://www.scopemed.org/?mno=169452 2014-11-23T02-41-54Z
Source: Journal of Clinical & Experimental Research
Hardik V. Vaniya, Jitendra M. Agrawal, Nirav M. Patel, Hiren R. Trivedi, Jayesh D. Balat, Shilpa P. Jadav, Dinesh A. Chawda.
Objective: The objective of this study was to determine antimicrobial drug use in newborns at a tertiary care neonatal intensive care unit, to identify educational/research priorities in neonatal drug therapy. Materials and Methods: This prospective observational study included 713 patients of neonatal sepsis over a period of 18 months. Data like name, age, sex, birth weight, gestational age, antibiotics used were recorded in the previously prepared case record form. Results: Number of patients admitted in early neonatal period was 467(65.5%) and number of patients admitted in late neonatal period was 246(34.5%). The mean age of all patients being admitted in NICU was 6.23 ± 5.86 days. The majority of neonates (92.56%) were prescribed 2 to 5 antibiotics and 29.59% of neonates were prescribed 2 antibiotics. Average number of antibiotics of all patients being admitted was 3.74 ± 1.38. Most frequently used antibiotics in decreasing frequency were: Amikacin (97.19%), ampicillin + sulbactam (60.17%), vancomycin (57.64%), ceftazidime (38.71%), cefotaxime (34.22%), ciprofloxacin (26.23%), piperacillin + tazobactam (19.07%). 73% drugs were given by generic name and 53.33% drugs were prescribed from the essential drug list. Mean length of stay in NICU of all patients being admitted was 7.59 ± 5.66 days. Conclusion: The present study provides valuable insight about the overall pattern of antimicrobial drug use profile in patients of neonatal sepsis of a tertiary care hospital. It is intended to be a step in broader evaluation of safety and efficacy of drug prescription in neonatal sepsis patients.
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Sun, 23 Nov 2014 01:53:42 GMT -08:00 http://www.scopemed.org/?mno=169452
Drug utilization study in post-operative patients in obstetrics and gynecology ward of a tertiary care teaching hospital http://www.scopemed.org/?mno=169425 2014-11-23T02-41-54Z
Source: Journal of Clinical & Experimental Research
Jitendra M. Agrawal, Nirav M. Patel, Hardik V. Vaniya, Hiren R. Trivedi, Jayesh D. Balat.
Objective: This study was aimed to identify pattern of drug use in post-operative patients in obstetrics and gynecology department in tertiary care hospital attached with medical college. Materials and Methods: We collected data from 615 postoperative patients in the obstetrics and gynecology ward of a tertiary care hospital over a period of 15 months. We analyzed the data using various drug use indicators given by the WHO. Results: The average number of drugs per encounter was 10.56. Antacids, analgesics, antibiotics, intravenous fluids accounted for majority of the drugs prescribed. 100% of the encounters were prescribed with an antibiotic. The percentage of encounters with an injection prescribed was 88.13% in our study. Out of 27 different drugs prescribed, 23 (85.18%) were from the National list of essential drugs, India (2011) and 21 (77.77%) were prescribed by their generic name. Average drug cost per encounter in a postoperative patient in our study was 1084.49 INR. Conclusion: The present study provides valuable insight about the overall pattern of drug used in postoperative patients in the obstetrics and gynecology unit of a tertiary care hospital. It is intended to be a step in broader evaluation of safety and efficacy of drug prescription in surgical wards of a teaching hospital.
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Sun, 23 Nov 2014 01:53:42 GMT -08:00 http://www.scopemed.org/?mno=169425
Knowledge, attitude and practice of non-medicinal alternative therapy in general population of Ahmedabad, India http://www.scopemed.org/?mno=170033 2014-11-23T02-41-54Z
Source: Journal of Clinical & Experimental Research
Gargi S. Panchal, Anju S. Mehta, Jigar R. Panchal, Jayesh D. Balat, Geeta Nair.
Objectives: The present study was undertaken to evaluate the knowledge, attitude, and practices (KAP) of non-medicinal alternative therapy in general population of Ahmedabad. Materials and Methods: A pretested KAP questionnaire comprising of 27 questions (knowledge 9, attitude 9, and practice 9) was administered to 300 general populations. The questionnaires were assessed for the type of responses regarding KAP of non-medicinal alternative therapy. Microsoft Excel worksheet (Microsoft Office 2007) and Chi-Square test were used for statistical analysis. Results: A total of 230 (76.66%) out of 300 peoples completed the questionnaire. Mean age was 40.13 ± 15.60 (mean + SD) years and male: female ratio is 1.25:1. Almost 85.22 % of people were aware of the non-medicinal alternative therapy through their relatives/friends (46.96%), newspaper (39.56%), television (36.12%) and internet (24.35%). Most people respond that these alternative therapies are mostly available in private setup than government hospitals. Around 74.35 % of people believed in non-medicinal therapy. Majority of people believed that alternative therapy build up body defence mechanism and balance the body systems. Almost 50.87% of people opined that alternative therapy better than allopathy in treating certain cases; because of cost effectiveness and it carries fewer side effects. Less than one-third (29.13%) has used non-medicinal alternative therapies on themselves mostly for stress disorders and depression.Conclusion: Knowledge and attitude towards the use of non-medicinal alternative therapies are good enough. However, practice of these among the people should be improved by integration of these alternative therapies with conventional therapy through some intervention.
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Sun, 23 Nov 2014 01:53:42 GMT -08:00 http://www.scopemed.org/?mno=170033
Prevalence of obesity and central obesity in middle aged population of Ahmedabad http://www.scopemed.org/?mno=172769 2014-11-23T02-41-54Z
Source: Journal of Clinical & Experimental Research
Neeta J. Vyas, Mona I. Chaudhary, Megha S. Sheth.
Objectives: To find out the prevalence of obesity using Body Mass Index (BMI) and prevalence of central obesity using Waist Circumference (WC) and to find out association between obesity, central obesity and socio-economic status (SES). Materials and Methods: A cross sectional study was conducted with 552 males and females aged 20-50 years was selected from community of Ahmedabad. People with kyphosis, scoliosis and subjects on anti-hyperlipidemic drugs or related anti-obesity drugs were excluded. Height, weight measurement and waist circumference of every subject was done and socio economic status was taken by using Kuppuswamy’s socio-economic scale. Results: Prevalence of obesity was found to be 15%. Forty seven percent had normal waist circumference, 32% were at mild risk and 21% were at moderate risk of cardiovascular disease according to the WC. A positive correlation between BMI and SES was found using Spearman correlation r = 0.53 (p
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Sun, 23 Nov 2014 01:53:42 GMT -08:00 http://www.scopemed.org/?mno=172769
Anticholinergic property of ethanol extract of Moringaoleifera Leaves: An in vivo and in vitro approach http://www.scopemed.org/?mno=172766 2014-11-23T02-41-54Z
Source: Journal of Clinical & Experimental Research
Solomon N. Ijioma, Chinenyenwa O. Nwosu, Charles Onyenegecha.
Objective: The anticholinergic property of ethanol extract of Moringa oleifera leaf extract was investigated using in vivo and in vitro experimental models. Materials and Methods: For the in vivo work, 30 mice (20-25g) were divided into 6 groups of 5 mice each. Groups 2-6 were treated with Atropine (0.1mg/kg) and graded doses of Moringa oleifera leaf extract (50, 100, 200, 400mg/kg) respectively while group 1 served as control. Thirty minutes after treatment all animals were given 0.2ml oral dose of activated charcoal. All animals were sacrificed and dissected in a further 30 minutes to measure the distance moved by the charcoal meal against the full length of the small intestine. For the in vitro studies, 6 guinea pigs (320-400g) and 6 rabbits (1.8-2.5kg) were used. The effects of extract on acetylcholine induced contractions in isolated guinea pig ileum and rabbit jejunum were found. Results: All doses of the extract inhibited acetylcholine induced intestinal motility significantly (P
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Sun, 23 Nov 2014 01:53:42 GMT -08:00 http://www.scopemed.org/?mno=172766
Comparison of analgesic effect of interferential therapy and transcutaneous electrical nerve stimulation on pressure pain threshold on young healthy individuals http://www.scopemed.org/?mno=172767 2014-11-23T02-41-54Z
Source: Journal of Clinical & Experimental Research
Vipra P. Dalal, Megha S. Sheth, Neeta J Vyas.
Objectives: The purpose of this study is to compare the analgesic effect of interferential therapy (IFT) and transcutaneous electrical nerve stimulation (TENS) on pain pressure threshold (PPT) in young healthy subjects. Materials and Methods: A comparative, crossover study involving 30 volunteers was conducted at Physiotherapy College. Inclusion criteria were healthy subjects, aged 18-25 years, taking no analgesic medication. Exclusion criteria were any painful musculoskeletal conditions, any contraindications to electrotherapy. IFT (Base-100 HZ, Sweep-0 HZ, 4PV90) and TENS (Frequency-100 HZ, Pulse duration-50microsecond) were given to the subjects using four electrodes placed covering the L1 to S2 areas for 15 minutes. PPT was taken from right erector spine muscle targeted as the central area of stimulation via mechanical algometer. Results: Data of 20 subjects were analyzed using SPSS 16 version. Paired t-test applied to see difference within the group and unpaired t-test applied to see difference between the groups. Mean difference is PPT scores in kgf were IFT (baseline=2.77±0.43, 15min=3.53±0.43, 60min=3.29±042), TENS (baseline=2.72±0.43.15min=3.53±0.41, 60min=2.96±0.42). Difference between baseline and 15min (IFT=0.76±0.27, TENS=0.62±0.28, p=0.13). Difference between baseline and 60min (IFT=0.51±0.22, TENS=0.24±0.19, p
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Sun, 23 Nov 2014 01:53:42 GMT -08:00 http://www.scopemed.org/?mno=172767
EFFECT OF NEURAL MOBILIZATION ON AGILITY IN ASYMPTOMATIC SUBJECTS USING SLIDERS TECHNIQUE” http://www.scopemed.org/?mno=164500 2014-11-23T02-41-54Z
Source: International Journal of Therapies and Rehabilitation Research
DabholkarTejashree, Dabholkar Ajit S, Kanwaljeet Gandhi.
Background & Purpose of the Study Neural mobilization is a part of manual therapy that has been reported to be an effective intervention for certain condition. Agility is an essential component in most field and team sports. Traditional definitions of agility have simply identified speed in directional changes as the defining component. There are different methods of delivering neural mobilization, including “sliding” and “tensioning” technique. Sliding techniques involve combinations of movements that result in elongation of the nerve bed at one joint, while reducing the length of the nerve bed at an adjacent joint. According to Micheal Shacklock (1995) the concept of neurodynamics must link mechanics and physiology and function of the musculoskeletal system Thus this study aims at doing so. 1. Effect of nervous tissue mobilization on lower extremity strength ,and mobility. 2. Effect of nervous tissue mobilization on agility • Methodology: subjects with only single positive neural tissue tension test were included in the study whereas those with Previous history of any neurological &musculoskeletal pathology were excluded from study. Outcomemeasures: lower extremity strength,range of motion,agility by t test 100 subjects were randomly assigned into two groups experimental and control groups. All patients were evaluated for baseline data of the above mentioned outcome measure. Experimental group were given sliding technique of neural mobilization whereas control group was given sham control mobilization. Results:results anlysed using paired and unpaired t test and correlation analysis was done.where statistically significant results were obtained for range ,strength and agility in experimental group.significant correlation was obtained for strength and agility component. Conclusion: Neural tissue mobilization is effective in improving agility of lower extremity
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Sat, 22 Nov 2014 17:54:38 GMT -08:00 http://www.scopemed.org/?mno=164500
FACTORS AFFECTING ADOPTION OF POULTRY INNOVATIONS BY RURAL FARMERS IN OTUKPO LOCAL GOVERNMENT AREA OF BENUE STATE, NIGERIA http://www.scopemed.org/?mno=170012 2014-11-23T02-41-54Z
Source: International Journal of Livestock Research
KUGHUR, P.G., Daudu, S. and Onu, O.E..
The study examined factors influencing adoption of poultry innovation in Otupko Local government Area of Benue State. The specific objectives were to analyze the selected socio-economic characteristics of the respondents, identify the types of innovations adopted, examine sources of information, analyze logit adoption of innovations and ascertain types of problems encountered. Primary and secondary data were collected, primary data were gathered with the use of structured questionnaire administered to randomly selected 120 respondents while secondary data were obtained through published and unpublished materials. Descriptive statistics and logit regression model were used for data analysis. The results revealed that 38.3% of the respondents were between 41-50 years, 55.8% had family size of 6-10 persons, 50.8% were secondary school leavers, and 67.5% had 1-5 years of poultry farming experience. The findings further revealed that 48.3% of the farmers adopted vaccination/diseases control and 45.8% obtained information on poultry innovations practices through the media. There is a significant relationship between level of adoption and number of birds kept by farmers and 89. 1 % of the respondents encountered diseases problem. It is recommended that public and private sectors should provide vaccines and veterinary services at the village level for the farmers.
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Sat, 22 Nov 2014 09:13:54 GMT -08:00 http://www.scopemed.org/?mno=170012
Strengthening exercises of respiratory muscles improve respiratory functions and posture in osteoporotic patients: an experimental study http://www.scopemed.org/?mno=166682 2014-11-23T02-41-54Z
Source: International Journal of Therapies and Rehabilitation Research
Salameh Bweir Aldajah, Hariraja Muthusamy.
[Purpose] The aim of this study is to examine the impact of thoracic muscles and diaphragm strengthening exercise on thoracic kyphosis, chest expansion, dyspnea, and Peak expiratory flow rate. [Subjects and Methods] Twenty patients were having osteoporosis with mild kyphosis and respiratory impairment. They were involved in strengthening exercises using 50% of 1 RM weights for forty minutes of resistive diaphragmatic exercise and thoracic muscles strengthening exercise, three times a week for 6 weeks. [Results] The Strengthening exercise improved the dyspnea from 8 to 5 in dyspnea grading scale, the chest expansion increased 2.5 inches (95% CI 44.96 to 47.40), peak expiratory flow rate increased 82.50 L/Min and range of motion of spine has increased 2 inches (95% CI 9.9 to12.7). [Conclusion] Strengthening exercise have positive impact and it should be part of any rehabilitation program for patient with osteoporosis and respiratory impairment.
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Sat, 22 Nov 2014 08:47:51 GMT -08:00 http://www.scopemed.org/?mno=166682
Career in Medicine: What factors influence medical students? http://www.scopemed.org/?mno=166087 2014-11-23T02-41-54Z
Source: Journal of Contemporary Medical Education
Adetunji Obadeji, Tunde Thomas Olo&#; ntoye, Olutoyin Lateef Oluwole.
Background: Despite high cost and competition for admission into medical schools in Nigeria, many students still pursue or choose medicine as a course of study. This study is aimed at identifying those factors influencing medical students in choosing medicine as a career. Methods: An anonymous questionnaire based survey of medical students (1st and 2nd year) of Ekiti University Medical School was done through a self-designed questionnaire. The first section of the questionnaire elicited information on students’ socio-demographics second section required the students to rank the factors influencing them in the choice of their career. Results: About two-third of the students were males, with a mean age of 21.50 years (standard deviation = 2.903). Most of the students indicated personal interest as the most significant factor influencing them in the choice medicine as a career, prestige of the profession (18.6%) is the second most cited factor while desire to care ranked (12.9%). None of the students was influenced to choose medicine as a career by the teacher. Conclusion: This study found out that there are several factors influencing the choice of career in medicine, however, personal interest of the students appear to be the most important, though with other modifiable factors.
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Sat, 22 Nov 2014 07:43:44 GMT -08:00 http://www.scopemed.org/?mno=166087
Causal inference at the population level http://www.scopemed.org/?mno=165092 2014-11-23T02-41-54Z
Source: International Journal of Research in Medical Sciences
Azam Yazdani, Eric Boerwinkle.
Three elements are needed to formalize a causal quantity at the population level: response, treatment, and the causal element, which are introduced here by notation. Inclusion of two essential causal assumptions, the monitoring and illumination assumptions, in a function distinguishes causal from association analyses. The discussion provides insight into causal inference.
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Sat, 22 Nov 2014 05:50:42 GMT -08:00 http://www.scopemed.org/?mno=165092
Peripartum cardiomyopathy—An unsolved mystery to an anesthesiologist http://www.scopemed.org/?mno=170570 2014-11-23T02-41-54Z
Source: International Journal of Medical Science and Public Health
H D Rashmi, H S Prajwal Patel, B T Shivaramu.
Cardiac diseases in pregnancy pose a multitude of challenges to both anesthesiologists and obstetricians. Peripartum cardiomyopathy is one of the rare causes of dilated cardiomyopathy in parturients with a great diagnostic difficulty. High degree of suspicion along with good clinical experience is needed for its diagnosis. Unfortunately, mortality from this ranges from 35% to 50%. We report a case of 21-year-old female parturient presenting at 37 weeks of gestation for emergency cesarean delivery with undiagnosed peripartum cardiomyopathy. She developed cardiac arrest soon after giving spinal anesthesia. She was successfully resuscitated and shifted to ICU for further management. Bedside echocardiography was conducted, which showed dilated cardiomyopathy with an ejection fraction of 32%.
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Sat, 22 Nov 2014 04:37:07 GMT -08:00 http://www.scopemed.org/?mno=170570
Linezolid resistant Staphylococcus aureus http://www.scopemed.org/?mno=169164 2014-11-23T02-41-54Z
Source: International Journal of Research in Medical Sciences
Pavani Gandham.
Linezolid is the only antibiotic available as an oral formulation for resistant staphylococcal infections. It is effective in skin & soft tissue infections, nosocomial pneumonias including VAP, infective endocarditis and MRSA meningitis. It is also effective in the eradication of both nasal & throat colonization of MRSA. Its high bioavailability and post antibiotic effect, ease of switching to oral therapy during its use and the fact that it can be used in patients of all ages, also in patients with liver disease and poor kidney function and its increased effectiveness over glycopeptides makes this drug a precious drug in the treatment of resistant staphylococcal infections. Linezolid resistance in staphylococcus is defined as a linezolid MIC of ≥8 mg/L. Reported Linezolid resistance in India and elsewhere is 2-20%. There is clonal dissemination of Linezolid Resistant Staphylococcus aureus (LRSA) within or across health care settings which demands continuous surveillance to determine the emergent risk of resistance strains and to establish guidelines for appropriate use. Clinical laboratories should confirm any LRSA preferably by a second method, prior to using linezolid for serious infections. Effective surveillance, more judicious use of this antibiotic, avoiding linezolid usage for empiric therapy in hospital acquired staphylococcus infections, optimization of the pharmacological parameters of the antibiotics in specific clinical situation, decreasing bacterial load by timely surgical debridement or drainage of collections, use of combination therapies would prevent the emergence of resistance to linezolid in staphylococcus aureus.
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Sat, 22 Nov 2014 02:09:57 GMT -08:00 http://www.scopemed.org/?mno=169164
A Study of Correlation of Size and Site of Perforation with Deafness http://www.scopemed.org/?mno=173459 2014-11-23T02-41-54Z
Source: The Southeast Asian Journal of Case Report and Review
Dr.Promod kharadi, Dr.Viral Prajapati, Dr.Keyur Mehta,Dr.Sushil Jha, Dr. Vishala Pandya.
Introduction: Otitis media is an inflammation of a part or all the mucoperiosteal lining of the middle ear cleft. It is a highly prevalent disease of the middle ear. Chronic suppurative otitis media is a serious health problem worldwide and it is more critical in developing countries where large percentage of the population lack specialized medical care, suffer from malnutrition and live in poor hygienic environmental conditions. because of the high incidence of conductive hearing loss caused by central perforations of tympanic membrane, the conflicting reports regarding the effect of perforations on hearing loss, this project has been under taken to study the clinical profile of CSOM & effects of tympanic membrane perforations on the degree of hearing loss. Material & methods: The present study was carried out in 500 patients (640 ears) presenting with unilateral or bilateral perforations of tympanic membrane, in the Department of E.N.T., Sir T. Hospital, Bhavnagar. It was carried out during the rime period of November 2008 to February 2010. Results: The perforations occupying all the four quadrants were maximum in 205 cases (i.e. 32.0%). In perforations involving two quadrant, it was observed that in perforations located over antero-superior + antero-inferior quadrants, those occupying 25-50% of effective vibratory surface area of tympanic membrane had significantly greater hearing loss than those involving
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Fri, 21 Nov 2014 22:14:18 GMT -08:00 http://www.scopemed.org/?mno=173459
Comparative study on lipid profile in tobacco chewers and nontobacco chewers http://www.scopemed.org/?mno=168695 2014-11-23T02-41-54Z
Source: National Journal of Physiology, Pharmacy and Pharmacology
Qazi Rais Ahmed, Narendra Gupta, Sapna Goyal, Shahid Jamal Ansari.
Background: Tobacco chewing is associated with millions of cases of chronic obstructive pulmonary diseases (COPD) and coronary artery diseases annually. Major forms of chewable tobacco contain toxicants and carcinogens. According to the World Health Report 2002, tobacco is the leading preventable cause of overall mortality as well as cardiovascular mortality worldwide. Aims and Objective: To reveal the effect of tobacco chewing on the lipid profile. Materials and Methods: This study was conducted to reveal the effect of tobacco chewing on the lipid profile in male subjects. The cross-sectional study was conducted in 60 male subjects aged 30–45 years. The subjects were divided into control group (n = 30) and study group (i.e., smokers; n = 30). All subjects were from either social class 2 or 3 according to Prasad’s modified social classification. About 5 mL venous blood sample was drawn after 10–12 h of fasting and lipid profile was analyzed. Results: No significant difference in anthropometric parameter of the control group and the study group was observed. Triglyceride and very-low-density lipoprotein cholesterol levels increased significantly (p < 0.001) in the study group (i.e., tobacco chewers) than in the control group. Total cholesterol and low-density lipoprotein cholesterol levels increased significantly (p < 0.05) in tobacco chewers than in the control group. The mean value of high-density lipoprotein cholesterol levels decreased but not significantly in tobacco chewers than in the control group. Conclusion: Strict measures should be taken up to control the prevalence of tobacco chewing habits and to prevent the risk for diseases such as cardiovascular diseases and COPD.
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Fri, 21 Nov 2014 20:10:43 GMT -08:00 http://www.scopemed.org/?mno=168695
Study of variations in the branching pattern of thoracodorsal nerve http://www.scopemed.org/?mno=164600 2014-11-23T02-41-54Z
Source: International Journal of Research in Medical Sciences
Santosh Manohar Bhosale, Nagaraj S. Mallashetty.
Background: Purpose of current study was to describe the variations in the origin of the thoracodorsal nerve of the posterior cord of brachial plexus and its distance of origin from mid-clavicular point in the South Indian population. These variations are important during surgical approaches to the axilla and upper arm, administration of anesthetic blocks, interpreting effects of nervous compressions and in repair of plexus injuries. The patterns of branching show population differences. Data from the South Indian population is scarce. Methods: Forty brachial plexuses from twenty formalin fixed cadavers were explored by gross dissection. Origin and order of branching of axillary nerve and its distance of origin from mid-clavicular point was recorded. Representative photographs were then taken using a digital camera (Sony Cybershot R, W200, 7.2 Megapixels). Results: In forty specimens studied, 72.5% of thoracodorsal nerves originated from posterior cord, which was predominant (75%) on the left side, 15% arose from axillary nerve which was observed in 20% of the right sided specimens and 12.5% had origin from the common trunk which was significant (15%) on the left side. In 32.5% of specimens, thoracodorsal nerve had origin at a distance of 4.1-4.5 cm, in 32.5% at a distance of 4.6-5.0 cm, in 17.5% at a distance of 5.1-5.5 cm, in 12.5% at a distance of 3.6-4.0 cm and in 5% at a distance of t more than 5.5 cm from mid-clavicular point. Conclusion: Majority of thoracodorsal nerves in studied population display a wide range of variations. Significant number of thoracodorsal nerve also takes origin from axillary nerve and from common trunk at various distances from a fixed point. Anesthesiologists administering local anesthetic blocks, clinicians interpreting effects of nerve injuries of the upper limb and surgeons operating in the axilla should be aware of these patterns to avoid inadvertent injury and this study provide the necessary insight into the branching pattern of the thoracodorsal nerve and its distance of origin. Further study of the origin of thoracodorsal nerve of posterior cord of brachial plexus and its distance of origin from mid-clavicular point is recommended.
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Fri, 21 Nov 2014 16:58:55 GMT -08:00 http://www.scopemed.org/?mno=164600
Pigment Epithelium-Derived Factor (PEDF): A Multifaceted and Functional New Therapeutic Agent http://www.scopemed.org/?mno=172325 2014-11-23T02-41-55Z
Source: Archives Medical Review Journal
Burcu Yener İlçe.
Pigment epithelium-derived factor (PEDF), a noninhibitory member of the serine protease inhibitor (serpin) family, is a naturally-occurring protein. The gene encoding human PEDF was localized to 17th chromosome and is around 16 kb. Mature gene product is 50 kDa and secreted as a soluable monomeric glycoprotein. Current studies show that PEDF is not only found in retinal pigment epithelium cells, but also widely expressed throughout the human body and in the tissues of almost all mammals. Pigment epithelium-derived factor (PEDF) was first discovered as a neurotrophic factor, an inducer of retinoblastoma cell differentiation, secreted by retinal pigment epithelial cells. Later, multiple and varied biological activities of PEDF have been found. The unique medicinal properties of this interesting protein are; anti-angiogenesis, anti-proliferative, tumor cell differentiation, anti-oxidant, and neuroprotective effects. Due to all these effects, recently PEDF has become the focus of attention of research topics. Today, studies focus on PEDF’s indirect (anti-angiogenesis) and direct antitumor effects (inhibiting cell division, tumor invasion and metastasis, promoting tumor cell apoptosis and differentiation). Thus, it is an emerging anti-tumor agent that may be able to target tumor cells and may be used instead of conventional chemotherapy in the future. In this review; briefly the structure and functions of PEDF, and the mechanisms in which PEDF plays an active role will be discussed.
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Fri, 21 Nov 2014 09:51:29 GMT -08:00 http://www.scopemed.org/?mno=172325
Transthoracic and transabdominal biopsy under-CT. http://www.scopemed.org/?mno=166220 2014-11-23T02-41-55Z
Source: Balkan Military Medical Review
Arjana Sina.
Introduction:Transparietal biopsy of thoracic and abdominal lesions is a rapid, safe method for their accurate diagnosis and for an appropriate treatment strategy. It is carried out under the direction of various imaging techniques, under ultrasound, under-CT etc. We commonly used semiautomatic coaxial biopsy needles 18G. Objective: The objective of this presentation is to show the importance of the use of this procedure prior to surgical intervention for suspected neoplastic formations. Discussion: Transparietal biopsy should be used routinely in all cases where suspicious evidenced neoplastic formations, for an accurate histological diagnosis, so that the patient will undergo to the best way of treatment.
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Fri, 21 Nov 2014 06:21:56 GMT -08:00 http://www.scopemed.org/?mno=166220
An Immediate Chair Side Treatment Option to Repair Fractured Post and Core: A Case Report http://www.scopemed.org/?mno=173350 2014-11-23T02-41-55Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
Abubakkar Vasthare, Mallika Shetty, Katheesa Parveen, Shaiq Gajdhar.
Fracture of an endodontically treated tooth,restored with a crown and an underlying post occurs frequently. This augments toa complex clinical situation that requires immediate attention. In this technique the existing crown was used after removing the fractured cast post. Fibre post was placed and the intaglio surface of the crown was duplicated using core build up material with aluminium foil acting as a separating medium between the crown and the core build up material. By this technique the same crown was recemented. This resulted in an optimal retention of the existing crown, thereby maintaining the existing esthetics and occlusal relationship. This is a simple chair side and immediate treatment option which can be used as a long term treatment option or a temporary one.
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Fri, 21 Nov 2014 05:44:58 GMT -08:00 http://www.scopemed.org/?mno=173350
Systemic Lupus Erythematosus and Autoimmune Hypothyroidism : A Case Report http://www.scopemed.org/?mno=173349 2014-11-23T02-41-55Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
Shaheena Appan Parambath, Rukmini Mysore Srikantiah, Poornima Manjrekar, Anupama Hegde.
Systemic lupus erythematosus (SLE) is a common autoimmune disease with the prevalence of 3.2 per 100000 in India. The reported association of SLE and thyroid disorders varies as much as 3.9 – 24 %. Here we present a 22 year old female with complaints of breathlessness, fatigue, myalgia, fever and decreased urine output since 2 days, who was brought to Medicine OPD, Wenlock District Hospital, Mangalore, with a past history of SLE on irregular treatment and follow up since 2 years. On examination she had pallor, generalized oedema, BP – 170/90 mm Hg, ejection systolic murmur in pulmonary area. Investigatory findings were positive for ANA and anti TPOand also were suggestive of anaemia, hypothyroidism and nephropathy.
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Fri, 21 Nov 2014 05:41:54 GMT -08:00 http://www.scopemed.org/?mno=173349
Alien Hand Syndrome: A Case Report and Approach to Rehabilitation http://www.scopemed.org/?mno=173348 2014-11-23T02-41-55Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
David Mackarel, Sowmy Murickal, Farah Kassim, Helen Banks, Shagufay Mahendran, Ganesh Bavikatte.
The Alien Hand Syndrome (AHS) is a phenomenon characterized by involuntary autonomous activity of the affected extremity, perceived by the patient as controlled by an external force. It may result from a number of conditions including brain injury, stroke, tumors and progressive neurological disorders. We report a case of AHS in a 60 year old right handed gentleman admitted with a subarachnoid haemorrhage secondary to a pericallosal aneurysm. He developed involuntary movement of his right hand including excessive grasp reflex and intermanual conflict. The current literature is scarce on specific rehabilitative strategies and therefore a number of approaches were used at different stages. He was noted to make good progress throughout his rehabilitation and by time of discharge his Alien Hand movements were diminished and interfering less in activity performance. The AHS may be under recognized and can hinder rehabilitation if not diagnosed. A number of rehabilitation approaches can be used and significant improvement can be expected.
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Fri, 21 Nov 2014 05:38:15 GMT -08:00 http://www.scopemed.org/?mno=173348
Development of Preliminary Questionnaire to Explore the Factors Causing Attrition from Occupational Therapy in India http://www.scopemed.org/?mno=173346 2014-11-23T02-41-55Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
Lipika Sachdeva, Ruby Aikat.
Background: There is a growing concern about the shortage of professionals in occupational therapy. So there is a need to address the reasons of why therapists are leaving the job market and why there is progression of attrition of professionals and students from occupational therapy. Objective: To develop a preliminary questionnaire for finding out the main factors causing attrition from occupational therapy in India. Materials and Methods: The study was carried out in three steps: the first was exploratory interview phase; the second was preliminary interview phase and the third step was establishment of face validity of the questionnaire. Results: A preliminary questionnaire was developed consisting of all the possible factors causing attrition. Conclusion: This questionnaire can be used further to carry out a survey in order to gather the main factors causing attrition from occupational therapy in India and various strategies can be formed for the improvisation of the scenario of occupational therapy in India.
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Fri, 21 Nov 2014 05:31:06 GMT -08:00 http://www.scopemed.org/?mno=173346
The Role of Serum Prostate Specific Antigen in Management of Prostatic Diseases – A Biochemical, Pathological and Clinical Audit of its Present Status http://www.scopemed.org/?mno=173345 2014-11-23T02-41-55Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
Reshu Tewari, Swasti Sinha, Anurag Bajpai, Manisha Dwivedi, Shankar Madhav Natu, Divaker Dalela, Apul Goel.
Background: Elevated serum levels of Prostate Specific Antigen (PSA) are used as a tumor marker in the detection of prostatic malignancy, in monitoring of wide spectra of prostatic diseases and in formulating various treatment plans of cancer. The use of PSA is a much debated issue in the international literature till date. Keeping the practical difficulties in mind often experienced by our clinicians, further comprehensive clinicopathological and biochemical studies are recommended to explore and utilize the full potential of PSA including its newer parameters especially tailored to suit the Indian population. Objectives: To locate the cutoff of serum PSA for establishing differential diagnosis of prostatic diseases and its impact on the therapeutic plan and assess the prognostic significance in context of North Indian population. Materials and Methods: All the participants (men above 50 years of age with Prostrate disease) were subjected to comprehensive Clinicoinvestigative work up. The previous clinical, radiological and pathologic findings were recorded in all patients on follow up for different prostatic diseases. Prostate biopsies and transurethral resection of prostate (TURP) specimens were procured wherever indicated and processed routinely. Results: Total 232 cases of different prostatic diseases as categorized on the basis of clinical and histopathological diagnosis, including Chronic Prostatitis, Benign prostatic hyperplasia (BPH), Benign hyperplasia of prostate with Prostatitis, High grade Prostatitis Intra Epithelio Neoplasia (HG-PIN) and Prostatic Carcinoma. The expected cut off value for subsequent total PSA was found to be 9.42 ng/ml at 80% sensitivity. In our study postulating that total PSA level at 9.42 ng/ml the probability of detecting true carcinoma cases would be 93% and only 7% cases would be likely to be missed. Conclusion: PSA levels have been shown to lose their diagnostic power to differentiate between different histological groups in high-risk category. Despite the low sensitivity of PSA, it continues to be an extremely powerful diagnostic test. This pilot study has revealed significantly higher values for different categories of Prostatic disease conditions.
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Fri, 21 Nov 2014 05:28:04 GMT -08:00 http://www.scopemed.org/?mno=173345
Respiratory symptoms and peak expiratory flow among sawmill workers in south western Nigeria http://www.scopemed.org/?mno=149589 2014-11-23T02-41-55Z
Source: Journal of Environmental and Occupational Science
Oluwatosin Adediran Adeoye, Adeleye Abiodun Adeomi, Adenike I Olugbenga-Bello, James O Bamidele, Olugbemiga L Abodunrin, Olukemi A Sabageh.
Aim: The aim of the study is to assess the respiratory symptoms and Peak Expiratory Flow (PEF) of sawmill workers. Methods: The comparative cross–sectional analytical study was carried out among 50 randomly selected sawmill workers in Osun State from March to May 2013. Age and sex matched controls consisting of 50 local government workers were also used. The respondents all had their Peak Expiratory Flow measured and also underwent Modified British Medical Research Council (BMRC) questionnaire on respiratory symptoms. Data was analysed using Statistical Package for Social Sciences version 16 and level of significance was set at p < 0.05. Results: The most prevalent respiratory symptoms among the study group were cough (60%) and sneezing (54%). The prevalence of respiratory symptoms such as cough (60%), phlegm production (46%), and sneezing (54%) were significantly higher among sawmill workers than the control (p-value
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Fri, 21 Nov 2014 05:08:56 GMT -08:00 http://www.scopemed.org/?mno=149589
Occupational health and safety practices among vehicle repair artisans in an urban area in Ghana http://www.scopemed.org/?mno=155661 2014-11-23T02-41-55Z
Source: Journal of Environmental and Occupational Science
Isaac Monney, Bismark Dwumfour-Asare, Isaac Owusu-Mensah, Richard Amankwah Kuffour.
Aim: The aim of the study was to assess the extent of work-related injuries and illnesses, access to first aid, use of Personal Protective Equipment (PPE), fire safety measures and hand hygiene practices among vehicle repair artisans. Materials and Methods: Study respondents were 100 vehicle repair artisans comprising of 28 Auto mechanics, 20 electricians, 26 welders, 18 sprayers, and 8 automobile interior designers selected by simple random sampling. Semi-structured questionnaires, extensive field observations and key informant interviews were used to collect primary data in 2013/2014 and analyzed with Minitab version 16 in 2014. Results: Close to two-thirds (64%) of the artisans have sustained work-related injuries mostly resulting from cuts and burns. Respondents’ marital status (P = 0.014) and the type of work (P = 0.037) were found to be significantly associated with the incidence of physical injury, in contrast to their level of education (P = 0.874) and work experience (P = 0.203). Seventy-eight percent of the artisans lack training in fire safety and besides, basic firefighting equipment are non-existent in the workshops visited. Self-medication after injury (55%; N = 64) and ignorance in first aid administration (92%) are common among the artisans. Further, due to the physical exertions required by their work, most artisans (N = 57) experience musculoskeletal disorders. Use of PPE (27%) and proper hand hygiene practices (28%; N = 98) are generally ignored by the artisans posing possible health risks. Conclusions: Vehicle repair workers need to be educated on the dangers associated with their work and the best practices to be adopted to curb or forestall these risks.
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Fri, 21 Nov 2014 05:08:56 GMT -08:00 http://www.scopemed.org/?mno=155661
Serum concentrations of organochlorine pesticides associated with diabetes and obesity in Northern Benin (West Africa) http://www.scopemed.org/?mno=157402 2014-11-23T02-41-55Z
Source: Journal of Environmental and Occupational Science
Colette Sylvie Azandjeme, Michele Bouchard, Francois Djrolo, Dismand Stephan Houinato, Hélène Delisle.
Aim: Diabetes rising prevalence is of great concern in Africa because of its socio-economic impacts in a context of limited access to health care. The inappropriate use of pesticides may add to the burden of diabetes in Africa. The present study was carried out in a cotton producing area of Benin in order to assess the relationship between the highest prevalence of diabetes observed in the country and organochlorine pesticide (OCP) exposure. Methods: A case-control study was conducted in 2011. A sample of 106 subjects with diabetes and 106 non-diabetic controls were paired by age, gender, ethnicity and residential area. Personal and socioeconomic information, along with anthropometric measurements were collected. Blood samples were assayed for total lipids and 14 OCPs by gas-chromatography coupled with mass-spectrometry. Data were recorded for the four detectable OCPs: p,p’-dichlorodiphenyldichloroethylene (p,p’-DDE), p,p’-dichlorodiphenyltrichloroethane (p,p’-DDT), β -hexachlorocyclohexane (β-HCH), and trans-nonachlor. Results: Serum levels of all four detected OCPs were consistently higher in diabetic subjects than in non-diabetic controls. The odds ratio of diabetes was nearly three-fold higher when comparing the third tertile of p,p’-DDE and p,p’-DDT and β-HCH levels with the first tertile, without adjustment for potential confounders. The association remained significant for p,p’-DDT (OR = 2.59; 95% CI: 1.17-5.42) and p,p’-DDE (OR = 2.11; 95% CI: 1.01-4.54) after adjusting for a family history of diabetes, abdominal obesity, and wealth index or education. Conclusion: Our data showed that exposure to p,p’-DDT and p,p’-DDE was associated with an increased risk of diabetes. These findings have major public health implications.
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Fri, 21 Nov 2014 05:08:56 GMT -08:00 http://www.scopemed.org/?mno=157402
Occurrence and the level of contamination of aflatoxin M1in raw, pasteurized, and UHT buffalo milk consumed in Sohag and Assiut, Upper Egypt http://www.scopemed.org/?mno=158758 2014-11-23T02-41-55Z
Source: Journal of Environmental and Occupational Science
Eman M Shaker, Eman E Elsharkawy.
Aim: This study evaluated the aflatoxin M1 (AFM1) in raw, pasteurized and ultra-heat treated (UHT) buffalo milk consumed in upper Egypt. Materials and Methods: Milk samples were collected from January to June 2013. The competitive enzyme-linked immunosorbent assay was applied. Results: All the tested samples were positive for AFM1, which were above the Egyptian regulations limits 0 ng/L. The raw milk showed 93% of samples were above the permitted limit set by the European Commission (EC), whereas 3.3% of samples exceeded US Food and Drug Administration (US FDA) tolerance limit. The pasteurized milk showed 100% and 13.5% of samples exceeded the EC, and US FDA, respectively. UHT milk Brand I and II showed 100% and 86.5% of samples were above EC, and 36.6% and 6.6% of samples exceeded US FDA, respectively. Conclusion: These results raise concerns about the milk consumed in Egypt and it must be monitored for AFM1 contamination.
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Fri, 21 Nov 2014 05:08:56 GMT -08:00 http://www.scopemed.org/?mno=158758
Pre-placement examination: A strategy to ensure benefit to the employees and employers http://www.scopemed.org/?mno=159137 2014-11-23T02-41-55Z
Source: Journal of Environmental and Occupational Science
Saurabh RamBihariLal Shrivastava, Prateek Saurabh Shrivastava, Jegadeesh Ramasamy.
Ergonomics is the “science of work” that encompasses different measures to ensure fitting the workplace to the worker. Among all the strategies implemented to safeguard the interests of both workers and employers, pre-placement examination, has been acknowledged as the foundation element. A comprehensive pre-placement examination assists in careful selection of workers, developing systematic plans to help workers to get acclimatized to their job, minimizing health risks to the workers, improving the quality of life of workers, reducing burden on the health care delivery system / insurance companies, maintaining good relations between employee & employer, building a healthy environment at workplace, and eventually augments the outcome of the industry. The pre-placement examination for a given job position is difficult to standardize worldwide, and thus should be tailor-made based on the characteristics of the employee; the type of equipment / process utilized to perform a specific job; routine policy of the industry; and amount of workload. To conclude, pre-placement examination is an integral component of the ergonomics and thus there is an immense need to implement it effectively in all settings to ensure benefit to both employees and employers, and eventually augment the productivity of the industry or economic growth of the nation.
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Fri, 21 Nov 2014 05:08:56 GMT -08:00 http://www.scopemed.org/?mno=159137
Solid-phase extraction employing 5-methyl-4-(2-thiazolylazo)resorcinol entrapped in sol-gel glass as a sorbent resin to remove Zinc ions http://www.scopemed.org/?mno=159748 2014-11-23T02-41-55Z
Source: Journal of Environmental and Occupational Science
Mohammed A. Zaitoun, Arab. K. El-Qisairi, Kammal A. Momani, Hanan. A. Qaseer, Wasim Alhalasah.
Aim: The ligand 5-methyl-4-(2-thiazolylazo)resorcinol (5-Me-TAR) was encapsulated in an optically transparent, inert and porous sol-gel glass to produce a solid resin. The synthesized composite (resin) was used as a solid phase extractant to remove (as a filter) zinc ions from water samples. Materials and Methods: A solution of the ligand in ethanol was mixed with selected alkoxysilanes in the presence of water to produce a homogeneous mixture. By hydrolysis and condensation of the alkoxysilanes, solid glass forms around the dopant. The ligand molecule is entrapped inside the glass pores, while small Zn(II) metal ions can diffuse into the pores where they are complexed by the ligand and retained inside the pores. Absorption and fluorescence spectroscopy were used to characterize 5-Me-TAR ligand and 5-Me-TAR-Zn complex both in solution and sol-gel glass. The sol-gel glass precursors were carefully selected to produce a glass composite material doped with the ligand with no leaching, especially when the glass is soaked in the solution. Results: Complexation using the batch method was employed, in which a known weight of the sorbent resin is mixed with a known concentration of Zn(II) ions. In order to attain the maximum metal ion complexation capacity; the filter was optimized to the optimum separation/pre-concentration conditions of analytes, including the effect of pH, capacity of the solid, equilibration time and coexisting ions; afterwards, the solution was filtered. The amount of zinc metal ion complexed/adsorbed was determined by the difference between the initial concentration in aqueous solution and that found in the supernatant, using flame atomic absorption. The optimum condtions (maximum uptake) was obtained at pH = 6 using 30 min shaking time, and the capacity of the solid was 0.153 mmol Zn/g. Conclusion: The ligand was successfully trapped inside the sol-gel pores, and no diffusion of the ligand was observed. Soaking of the sorbent in a solution containing Zn(II) ions results in diffusion of the zinc ions through the sorbent pores into the ligand for complexation.
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Fri, 21 Nov 2014 05:08:56 GMT -08:00 http://www.scopemed.org/?mno=159748
Antimicrobial Properties of 39 Essential Oils against Thirteen Food-borne Microorganisms; Efficacy and Environmental Hygiene of Prunus armeniaca in Raw Food Preservation under Cold Storage http://www.scopemed.org/?mno=161269 2014-11-23T02-41-55Z
Source: Journal of Environmental and Occupational Science
Magda Magdy Abd El-Salam, Sahar Yassin Ibrahim.
Aim: The present study investigated the antimicrobial properties of 39 diversified essential plant oils (EOs). The most bioactive EO was selected and tested for its environmental hygiene efficacy in the preservation of stored raw food. Methods: The antimicrobial efficacy of 39 EOs was examined against 13 representative food-borne microorganisms. Minimal inhibitory concentration (MIC) of extracted apricot (Prunus armeniaca) seed EO was evaluated. Different concentrations of extracted oil were applied to four types of low-fat raw foods under cold dry storage. Results: The results of the microbial sensitivity assay showed considerable positive responses to only 23 out of 39 EOs. Pru. armeniaca exhibited the most significant antimicrobial efficacy. Different MIC values of extracted Pru. armeniaca oil were documented as a result of strain variability of representative food-borne microorganisms. Extracted apricot EO concentration delayed bacterial food spoilage at 1000 μgml-1 while fungal spoilage delayed at 2000 μgml-1. Total bacterial viable count (TVC) of raw food samples treated with 1000 μgml-1 oil decreased sharply when compared with TVC of samples not treated with oil. Fungal growth was completely inhibited in samples treated with 2000 μgml-1 oil. Statistical analysis showed a significant association between the minimal inhibitory concentrations (MIC) of Pru. armeniaca EO and the growth of the 13 representative food-borne microorganisms, it was mostly 500μgml-1. Conclusion: The achieved study results support using of Pru. armeniaca EO in controlling shelf-life of raw foods stored under dry cold conditions.
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Fri, 21 Nov 2014 05:08:56 GMT -08:00 http://www.scopemed.org/?mno=161269
Ambient air’s volatile organic compounds and potential ozone formation in urban area, Bangkok, Thailand http://www.scopemed.org/?mno=163866 2014-11-23T02-41-55Z
Source: Journal of Environmental and Occupational Science
Tanasorn Tunsaringkarn, Tassanee Prueksasit, Daisy Morknoy, Saowanee Semathong, Anusorn Rungsiyothin, Kalaya Zapaung.
Aims: The study were evaluated for the presence of the ambient air volatile organic compounds (VOCs) (benzene, toluene, ethylbenzene and xylene [BTEX] and carbonyl compounds [CCs]) at the university, roadside and residential areas in order to assess the applicability for prediction of ozone formation in ambient air of these in urban area, Bangkok, Thailand. Methods: The ambient air VOCs levels were evaluated by the gas chromatography/flame ionization detector for BTEX analysis and the high-performance liquid chromatography/UV-visible detector for CCs analysis. Results: The comparison of VOCs levels in those areas showed that the roadside area had the highest VOCs levels (of toluene and benzene levels), while the residential area had the lowest of benzene level. However, the benzene levels of all studied-areas were higher than ambient air quality standard. The contributions of hydrocarbons to local ozone formation potential were evaluated in terms of maximum incremental reactivity. Our results showed that the largest contributors to ozone production in Bangkok were toluene and formaldehyde (possibly from the emission of biofuel motor vehicle exhaustion). The roadside area also had the highest ozone formation potential. The aromatic hydrocarbon was the major contribution to anthropogenic emissions of VOCs. However, anthropogenic emissions and photochemistry are mainly transported VOCs to ozone formation. Conclusion: There was the highest VOCs level at roadside area and also was the largest amount of ozone level from chemical reactions. Therefore, it is a need for more research and the environmental protection policy because it may have serious health risk from these pollutants in these areas.
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Fri, 21 Nov 2014 05:08:56 GMT -08:00 http://www.scopemed.org/?mno=163866
Papillary cystadeno carcinoma – A Very Rare Case Report http://www.scopemed.org/?mno=173334 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Dr.Sherin.A.Khalam, Dr.Ninan Thomas, Dr. Anroop A.
Papillary cystadenocarcinoma is an extremely rare malignant neoplasm characterized by cysts and papillary endophytic projections1. It was first defined in 1991 by World Health organization as a separate entity1,2. Major locations of this neoplasm are the parotid gland, the sublingual gland, and minor salivary glands, while occurrence in the submandibular gland is extremely rare3. We present a case of papillary cystadenocarinoma arising from the submandibular gland in a 67-year-old male patient. Further, we have discussed the cytological and histopathological features of this rare entity and reviewed the current literature.
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Fri, 21 Nov 2014 02:21:11 GMT -08:00 http://www.scopemed.org/?mno=173334
Carotico clinoid foramen and interclinoid bars - A case report http://www.scopemed.org/?mno=173332 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Usha Kothandaraman, S.Lokanadham.
We have observed one skull with bilateral carotico clinoid foramen and interclinoid bars formed by fusion of carotico clinoid ligaments between the anterior, middle and posterior clinoid processes. The incidence of the complete type of bilateral carotico clinoid foramen in our study was 1 out of 20 human dry skulls (5%). The bilateral formation of interclinoid bars and carotico-clinoid foramen have high significance due to their rare occurrence. Carotico clinoid foramen may cause changes in the internal carotid artery in clinoid segment which may cause compression of cavernous sinus due to its medial position. Our study provides a guide to neurosurgeons in surgical approaches to prevent fatal complications while performing regional surgeries.
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Fri, 21 Nov 2014 02:11:58 GMT -08:00 http://www.scopemed.org/?mno=173332
Role of Remedial Exercises and Mobilisation to Reduce Pain and Improve Functional Abilities in Idiopathic Polyarthritis - A Case Report http://www.scopemed.org/?mno=173329 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Sanjiv kumar, Jeba Chitra, Siddharth Mishra.
Background: Idiopathic polyarthritis is a rare entity and remains to be a challenging case to diagnose and manage which has the major impact on the physical, social and psychological aspect of the affected individual. Objective: The aim of the report is to determine the role of remedial exercises and mobilisation to reduce pain and restoration of function in patient with idiopathic polyarthritis. Case report: We report the case of 47 year female presenting with history of severe pain and stiffness in her knee joint followed by shoulder, elbow, wrist and ankle joint with swelling in both hands and feet’s . The pain and stiffness was managed by remedial exercises and mobilisation. Conclusion: A remedial exercises along with mobilization is an effective intervention for reducing pain and restoration of functional ability and to increase functional independency.
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Fri, 21 Nov 2014 01:57:32 GMT -08:00 http://www.scopemed.org/?mno=173329
Mammary Tuberculosis: A case series of six patients and review of literature http://www.scopemed.org/?mno=173328 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Shweta Rana, Puja Sharma, Pawan Singh, Rajesh Chaurasia.
Introduction: Mammary Tuberculosis is a rare entity and may be mistaken as carcinoma breast or pyogenic breast abscess because of its non specific clinical and radiological findings. Microscopy and culture are frequently negative because of its paucibacillary nature and the diagnosis is often one of exclusion. We present a case series of six consecutive patients with mammary tuberculosis, seen over a six month period (June 2013 to December 2013) from SHKM, GMC Mewat, Haryana. Case presentation: Cases with either histopathological diagnosis of necrotizing granulomatous mastitis with or without acid fast bacilli positivity, cytopathological diagnosis of necrotizing granulomatous mastitis with or without acid fast bacilli positivity or both were included in the study. Their clinical, radiological and pathological data was reviewed. All the patients were women. The average age at presentation was 29.16 years (24 to 40 years). All the six cases were initially subjected to Fine Needle Aspiration Cytology (FNAC). Excision biopsy was done in only four cases. Final diagnosis was obtained via FNAC (2 cases), excision biopsy (4 cases). Acid fast bacilli were seen on Ziehl-Neelsen (ZN) staining on histopathology in one out of four cases and in two out of six cases on FNAC. Conclusion: Mammary tuberculosis typically presents with lump in breast and being an uncommon disease, can be mistaken as carcinoma breast or breast abscess. The diagnosis can be established or suggested by FNAC in majority of cases.
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Fri, 21 Nov 2014 01:46:46 GMT -08:00 http://www.scopemed.org/?mno=173328
Isoniazid Induced Hepatitis and Psychosis in a Single Patient – Case report http://www.scopemed.org/?mno=173327 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Ravouf Parvaiz Asimi, Irfan Ahmad Shah, Sawan Verma, Irfan Yusuf, Mansoor Ahmad Dar, Mudasir mushtaq, Shiekh nawaz.
A 22-year-old female who was a known case of tubercular meningitis on anti-tubercular therapy, presented to the emergency room with complaints of recurrent vomiting, markedly reduced appetite, yellowish discoloration of eyes, abnormal behaviour and delusion of reference. There was no prior history of psychiatric illness or hepatitis like illness. Her liver enzymes were elevated more than 3 times of reference value and mental status examination revealed features of acute psychosis. Hepatitis resolved completely after isoniazid was discontinued and psychosis resolved fully only after treatment with amisulpride was begun. The patient was later rechallenged with isoniazid successfully and remained symptom-free 3 months after discharge from the hospital. This is an unusual presentation where both hepatitis and psychosis due to isoniazid occurred together simultaneously.
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Fri, 21 Nov 2014 01:42:08 GMT -08:00 http://www.scopemed.org/?mno=173327
Non Diabetic Lipemia Retinalis –A Rare Case http://www.scopemed.org/?mno=173326 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Dr. Tarakeswara Rao. Attada, Dr.V.Mahathi, Dr.S. Laxmi, Dr. V.V.L. Narasimha Rao.
A rare case of Nondiabetic lipemia Retinalis in a 30 year old female , who presented not only with eruptive xanthomas on hands, legs and high triglycerides but also ocular manifestations described in lipemia retinalis. The blood sugar levels within normal limitis.The clinical presentation varies with levels of triglycerides. Lipema Retinalis usually not associated with any ocular symptoms. Lipemia retinalis is a reliable parameter of high levels of triglycerides and should be considered as an important clue while making a diagnosis.
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Fri, 21 Nov 2014 01:37:35 GMT -08:00 http://www.scopemed.org/?mno=173326
A Rare entity of Primary Splenic Hydatidosis – A case report http://www.scopemed.org/?mno=173323 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Kate Madhuri S, Mane Sheetal V, Awari Ramesh.
Hydatid disease is endemic in farming areas but can occur worldwide. It is caused by infection with Echinococcus granulosus leading to development of cysts. The most common site of disease is liver and lungs. Other sites such as spleen, pancreas, heart and muscles are rarely affected. Isolated splenic hydatidosis is a rare entity and only small clinical series or case reports have addressed the issue of splenic echinococcosis. We hereby report a case of giant hydatid cyst in spleen of 39 year old female. Splenectomy was done and diagnosis was confirmed on histopathological examination. Thus hydatid disease should be kept in mind while dealing with cystic lesions of spleen.
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Fri, 21 Nov 2014 01:29:58 GMT -08:00 http://www.scopemed.org/?mno=173323
Spindle cell carcinoma (Sarcomatoid carcinomas) of Head and neck: A Case Series http://www.scopemed.org/?mno=173322 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Vikas Warikoo, Krunal Solanki, Kiran C Kothari, Mahesh H Patel, Dinesh Sharma.
Spindle cell carcinoma of head and neck, a subtype of squamous cell carcinoma is a unique and rare neoplasm, composed of both malignant epithelial and mesenchymal components. A series of 10 patients with Spindle cell carcinoma is presented, along with an analysis of potential prognostic factors, outcome following treatment, and patterns of failure. Details of patients were reviewed from hospital records of surgical, radiotherapy and pathology departments.
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Fri, 21 Nov 2014 01:20:56 GMT -08:00 http://www.scopemed.org/?mno=173322
Comparative Study of Laparoscopic Versus Open Low Anterior Resection (LAR) http://www.scopemed.org/?mno=173320 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Vikas Warikoo, Krunal Solanki, Kiran C Kothari, Mahesh H Patel, Dinesh Sharma.
Introduction: Rectal cancer is among the most common cancers and one of the leading causes for cancer death in both males and females. Surgery is the mainstay of treatment, with about 84% of patients with cancer of rectum treated surgically, with or without chemotherapy and/or radiotherapy. Material & methods: From August 2011 to February 2014, 44 patients with rectal malignancy undergoing LAR were included in the study, out of which 19 (43%) underwent laparoscopic LAR & 25 (57%) underwent open LAR. Both type of surgeries were performed by surgeons with similar expertise and experience in a single institute to make comparison and conclusions valid. Conclusion : Laparoscopic LAR surgery results have been shown to be similar in safety and oncological adequacy and completeness of the resection compared to open procedure, with benefit of reduction in the morbidity, hospital stay, returns to normal daily activities ,lesser blood loss and analgesia requirement. These favourable findings of laparoscopic resection for colorectal malignancy warrant further longer follow-up and results of prospectively randomized studies.
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Fri, 21 Nov 2014 01:11:23 GMT -08:00 http://www.scopemed.org/?mno=173320
Prospective Study of IntraCranial Tumour http://www.scopemed.org/?mno=173318 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Dr. Farzana Kothari, Dr. Amrish Shah.
Background and objective: A brain tumor or intracranial neoplasm occurs when abnormal cells from within the brain. There are two main types of tumors: malignant or cancerous tumors and benign tumors.1 Cancerous tumors can be divided into primary tumors that started within the brain and those that spread from somewhere else known as brain metastasis tumors.2 Method: Fifty cases of intracranial tumours were studied These tumours were studied for their pathology, incidence in relation to age group, sex and sites of occurence. Results: Histopathological examination of these tumours revealed that astrocytomas(28%) and meningiomas (22%) comprised a large majority of the total number of tumours. The incidence of each type of the tumour in the present study is compared to the incidence in other large published series. Conclusion: The average age of the patients from whom the material was obtained was 42.99 years in our study. The highest incidence age group of astrocytoma which formed the majority of the total tumours in our study was 4th declade.There were 46% males and 54% females in our study, the female incidence being higher due to preponderance of meningiomas and Schwannomas in them.We found 64% supratentorial and 36% infra-tentorial lesions in our study. Intra operative squash preparations play an important role in early diagnosis of the tumours.
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Fri, 21 Nov 2014 01:03:27 GMT -08:00 http://www.scopemed.org/?mno=173318
A Prospective Study of 100 Case of Colonoscopic finding in a Patients of Colorectal Disorder http://www.scopemed.org/?mno=173316 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Dr. Hitesh Chitroda, Dr.Samir Shah, Dr.Firduas Dekhaiya, Dr.Bhavesh Astik, Dr.Sandip Parmar.
Background: Colo-rectal disorders mainly consist of ulcerative colitis, Crohn’s colitis, malignancy, polyp, Diverticular disease, stricture, tuberculosis hemorrhoids, anal fistula, and fissure. Now a Days introduction of ultrasound and color Doppler with colonoscopy and virtual colonoscopy increases the diagnostic as well as therapeutic value. Aims and Objectives: Study the commonly encountered cases of colo-rectal disorders and their management and regular follow-up. To predict the prognosis, to do colonoscopy guided biopsy for detecting of colorectal carcinoma and a screening tool for every patient of age more than >50 years. Materials and Methods: We have selected 100 patients had acomplain of abdominal pain, discharge in stool, constipation, diarrhea and screening of known case of inflammatory bowel disease and malignancy. Pre operative bowel preparation was done. Results: Male (58%) are more affected than female (42%) in colorectal disorders. During colonoscopy 55% patients having normal colonoscopy finding, 30% having colitis, 7% having malignancy, 4% having a polyp. Conclusion: Colonoscopy has very useful diagnostic and therapeutic advantages in detecting and treating colonic pathologies.
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Fri, 21 Nov 2014 00:48:17 GMT -08:00 http://www.scopemed.org/?mno=173316
Study of Lipid Profile in Obese and Non-Obese Subject http://www.scopemed.org/?mno=173315 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Dharmishtha Dodiya, Hina Banker.
Introduction: The lipid profile is a blood test done to assess the status of fat metabolism in the body. This includes measuring lipids (fats) and its derivatives known as lipoproteins. Lipoproteins are compounds containing fat and proteins and include free cholesterol, cholesterol esters, triglycerides, phospholipids and Apoproteins. Objective: To study the alteration of lipid profile in obese patient and to evaluate the lipid profile in non-obese and obese patient in different age Material & methods: The study was carried out in Physiology department of Smt.N.H.L.M.Medical College & V.S. general hospital, during a time period from June 2008 to November 2010. Total sixty five obese subjects, coming for health check up at our institute ,were selected for this study .The age group of subjects is between 20-70 yrs. Results and Conclusion: For these study total 100 cases were taken out of which 65 are obese and 35 were non-obese. From our study it is quite evident that majority of obese are above 40 yrs of age. In both the group males are more than females it could be possible that males may go in for investigations earlier as compared to females.
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Fri, 21 Nov 2014 00:37:42 GMT -08:00 http://www.scopemed.org/?mno=173315
Anatomical variation in position, location and number of fibular nutrient foramen http://www.scopemed.org/?mno=173314 2014-11-23T02-41-55Z
Source: The Southeast Asian Journal of Case Report and Review
Dr. Satish Patel, Dr. Jagdish Chaudhari, Dr. Bharat Sarvaiya, Dr. Badal Jotania, Dr. S.M. Patel, Dr. S.V. Patel.
Background: Fibula is a slim bone. Its shape varies with the strength of the muscles attached. The fibula though transmits insignificant force in walking, fibula is an important bone for muscle attachment and significant source of bone graft. It has a proximal head narrow neck, long shaft and a distal lateral malleolus. The knowledge and position of the nutrient foramina of fibula is important to proceed with the free implant of the vascularized bone graft In harvesting the fibula, this segment is always taken, as the graft is more reliable regarding anastomosis, which includes endosteal and peripheral vascularization and associated with less post operative morbidity. Material and methods: 240 adult fibula of unknown sex. from: Govt. Medical college-Bhavnagar, K.J.Mehta Dental College, Amargadh Bhavnagar, Smt. N.H.L. Municipal Medical college Ahmadabad, B.J.Medical college, Ahmadabad, Gujarat were studied Above mentioned. Measurements were taken with Vernier Caliper. Results: Number: Out of 240 fibulae examined, 192(80%) showed a single foramen while 48(20%) possessed double foramina. Position: The nutrient foramina of fibulae were situated in the middle third of the bone with a foramen index ranging between 35.23% and 67.69% of the bone length of the total 288 foramina, 280(97.2%) existed in the middle third and8 (2.7%) were in the distal third There were no foramina in the proximal third of the whole fibular foramina, 192 (66.6%) were on the medial crest of the posterior surface, 88(30.5%) on the posterior surface between medial crest and interosseous border and 8 (2.7%) on lateral surface Size: Of all fibular foramina, 32(11.1%) were dominant foramina while 256(88.8%) were secondary. Direction: Of the total 288 nutrient foramina observed in the fibulae, 224 (77.71%) was directed distally; while the direction of 64(22.2%) was proximally Obliquity: There was no change in the obliquity of the foramina, whether they were in the centre of bone or nearer to the ends. Conclusion: Fibula of 35.23 cm – 67.69 cm is available for grafting among Indians. The metric estimation of the position of the nutrient foramen of the fibula could assist in harvesting vascularised graft of the bone.
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Fri, 21 Nov 2014 00:32:40 GMT -08:00 http://www.scopemed.org/?mno=173314
Mitochondrial Uncoupling Proteins in the Brain: Their Structure, Function and Physiological Roles [Beyindeki Mitokondriyal Eslesme Bozucu Proteinler: Yapısı, Islevi ve Fizyolojik Rolleri] http://www.scopemed.org/?mno=1807 2014-11-23T02-41-55Z
Source: Medicine Science | International Medical Journal
Yavuz Erden, Suat Tekin, Sevda Kirbag, Suleyman Sandal.
Uncoupling proteins (UCPs) which belong to mitochondrial anion carrier family are important because of their special distribution to different tissues and their intrinsic physiological function at those tissues. The UCP1 found in the brown fat tissue and being the most well-known member of this family takes in charge for arranging energy metabolism and body temperature. Other members of UCPs family (UCP2, UCP4 and UCP5) demonstrate a broad spread in neural field. Neural UCPs participate in regulating neuroendocrine functions, in forming free radicals production, in conveying neuroprotection and neurotransmission in central nervous system. The aim of this compilation is to provide a better understanding of physiological roles of neural UCPs.
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Fri, 21 Nov 2014 00:16:48 GMT -08:00 http://www.scopemed.org/?mno=1807
The patient registry: a high-impact tool for real world evidence http://www.scopemed.org/?mno=173307 2014-11-23T02-41-55Z
Source: International Journal of Medical Research & Health Sciences
BarickUttam, MohantyRituraj, GowdaArun.
Background: In this world of seemingly infinite data across domains, one strives to acquire better tools and methodologies to fully exploit available data. This process begins with meticulous planning to gather relevant information and continues until there is an output in the form of credible evidence. The ability to generate real-world evidence would take such a process to new level: the factors that influence these processes under real-world conditions are varied, unpredictable, and unregulated. Results obtained in highly regulated or controlled conditions are universally accepted and sought after for regulatory approvals, but performance indicators in the real world will set the tone for the future. Hence, the demands for very reliant and robust tools and mechanisms for gathering evidence are all the more prominent and necessary. Patient registries fill this gap and stand tall among the various tools that could deliver the desired end results with acceptable accuracy. Over the years, pharmaceutical companies, along with policymakers and other stakeholders, have been actively involved in the development of such registries. Aims: Here we provide an overview of the usefulness of registries for the various stakeholders in healthcare in terms of conduct, approach, and barriers to initiating such studies. Conclusion: One of the impediments for the wider appeal and utility of registries is low awareness among the public and policymakers. Incorporating them as a part of the standard global healthcare system would involve setting up a regulatory framework.
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Thu, 20 Nov 2014 23:22:49 GMT -08:00 http://www.scopemed.org/?mno=173307
Stem cells in endodontic therapy http://www.scopemed.org/?mno=173306 2014-11-23T02-41-55Z
Source: International Journal of Medical Research & Health Sciences
Sita Rama Kumar M, Madhu Varma K, Kalyan Satish R, Manikya kumar Nanduri.R, Murali Krishnam Raju S, Mohan rao.
Stem cells have the remarkable potential to develop into many different cell types in the body. Serving as a sort of repair system for the body, they can theoretically divide without limit to replenish other cells as long as the person or animal is still alive. However, progress in stem cell biology and tissue engineering may present new options for replacing heavily damaged or lost teeth, or even individual tooth structures. The goal of this review is to discuss the potential impact of dental pulp stem cells on regenerative endodontics.
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Thu, 20 Nov 2014 23:21:17 GMT -08:00 http://www.scopemed.org/?mno=173306
Prescription event monitoring stud to assess the safety profile of oral natural micronized progesterone sustained release in India http://www.scopemed.org/?mno=173305 2014-11-23T02-41-55Z
Source: International Journal of Medical Research & Health Sciences
Purandare AC, Hajare A.
Background:Role of natural micronized progesterone (NMP) in various therapeutic conditions, including luteal phase correction and luteal phase support (LPS) has been very well highlighted1, 2. It offers better safety profile on long term administration with ancillary immunomodulatory and anti-inflammatory properties3. Oral NMP in the form of sustained release (SR)offers better patient compliance due to once a day dosage schedule4. This employs a novel matrix technology for the release of progesterone in small pulses into the systemic circulation over a period of 24 hours, thereby minimizing the hepatic metabolism related side effects including sedation or drowsiness. Objective: To study the safety profile of oral NMP SR (Dubagest SR), a PEM study was conducted in the outpatient settings in India.Materials and methods: PEM study is a method employed worldwide to provide useful safety information on the drug when prescribed in ‘Real-life clinic settings’. Patients with bad obstetric history (BOH) or unexplained infertility were prescribed either 300 or 400 mg SR once a day following induction with Natural or Stimulated ART cycle for two months. Safety information related as ‘Events’ was captured on the Study questionnaire sheet provided to 35 doctors across India for five patients at each centre between March and May ’13.Results: 153 patients completed the study with a mean of 27yrs& 55kgs. In infertility patients with BOH 87% patients had ≥ 2 abortions. The formulation was prescribed for Luteal Phase Support in Unexplained infertility (43.8%) or BOH (50%) and Secondary Amenorrhoea (5.9%). Oral NMP 300 mg SR was the most commonly prescribed formulation. The formulation was well tolerated with side effects including drowsiness (0.6%), hyperemesis (1.3%)& giddiness (0.6%) that were mild and transient. Two patients reported Spotting that disappeared on continued therapy and in other case probably related to reappearance of menses. Conclusion: Oral NMP SR is a clinically feasible option for LPSespecially in BOH cases having Insignificant side effect profile for improved compliance.
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Thu, 20 Nov 2014 23:19:37 GMT -08:00 http://www.scopemed.org/?mno=173305
Value of electrocardiogram in predialytic chronic kidney disease patient without known coronary artery disease http://www.scopemed.org/?mno=173304 2014-11-23T02-41-55Z
Source: International Journal of Medical Research & Health Sciences
Dutta PK, Das S.
Chronic Kidney disease (CKD) is a pressing public health burden occurring in about 10% of the population. The majority of them die before reaching End Stage Renal Disease (ESRD) due to cardiovascular disease (CVD). Hypertension (HTN) and anaemia are two reversible factors for progression of CKD. Besides asymptomatic coronary artery disease, the electrolyte abnormalities such as hyperkalaemia and hypocalcaemia also subject these patients to sudden cardiac death. This study is aimed at to see the changes in electrocardiogram (ECG) in hospitalized predialytic CKD patients due to these abnormalities. Methods: This is a 6 months cross-sectional study carried out at Chittagong Medical College Hospital in Chittagong, Bangladesh. 50 patients with stages 3, 4 and 5 CKD were recruited from the Nephrology and Medicine wards. Patients with prior history of coronary artery disease, cardiomyopathy, valvular heart disease and dialysis were excluded. All had their standard 12–lead electrocardiogram (ECG) recorded and various findings were critically studied and interpreted independently by two consultant physicians including a cardiologist. Data analysis was done using SPSS version 19. Results: LVH (left ventricular hypertrophy) (66%), LAE (left atrial enlargement) (30%) and unrecognized myocardial infarction (28%) were very common ECG abnormalities in our predialytic CKD patients. HTN, anaemia, late presentation, and male gender appear to be associated with ECG abnormalities. Though 28 patients (56%) were hyperkalaemic only 9 patients (38%) of them had tall tented T wave in ECG. Conclusion: Detection of HTN and anaemia in male predialytic CKD patients will arouse suspicion which will help in early detection of cardiac outcome by ECG abnormality which will help in taking treatment strategy in resource limited country.
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Thu, 20 Nov 2014 23:17:53 GMT -08:00 http://www.scopemed.org/?mno=173304