ScopeMed - RSShttp://www.scopemed.orgScopeMed RSSen-us Copyright © 2011 ScopeMed All rights reserved. ScopeMedhttp://www.scopemed.org/img/logo-scopemed-ttk.gifhttp://www.scopemed.org 2016-12-09T20-52-54Z Infra-Dreaming and Dream-Awake States: A Case Study http://www.scopemed.org/?mno=252194 2016-12-09T20-52-55Z
Source: Sleep and Hypnosis: A Journal of Clinical Neuroscience and Psychopathology
Jorge Conesa-Sevilla.
The rare occurrence of the continuation and magnification of dream content, “reality,” and “free-wheeling” dynamics (fleeting, poignant, meaningful, and meaningless), intersecting with and interspersed within awake reality and consciousness is here described, for lack of better terms or known conditions, as infra-dreaming, or infra-reality. This term is borrowed from a literary source, “infrarealism,” because it captures the seamless spilling over of dream and dream-like consciousness into wakeful consciousness with a melding of the two, without obvious or diagnosed mental disorders, but with significant (observable) temporary deficits in short and long term memory.
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Fri, 09 Dec 2016 08:14:21 GMT -08:00 http://www.scopemed.org/?mno=252194
Hypnosis and Postmodernism: Multicultural Applications http://www.scopemed.org/?mno=252193 2016-12-09T20-52-55Z
Source: Sleep and Hypnosis: A Journal of Clinical Neuroscience and Psychopathology
Marty Sapp.
This article described the connection between hypnosis and postmodernism. Sapp (2015a) defined hypnosis as having features of dissociation and absorption. Also, Sapp provided applications of hypnosis to various cultural groups. Postmodernism generally includes solution-focused brief therapy, narrative therapy, feminist psychotherapy, positive psychology, family systems therapy, and multicultural counseling. The major thesis of this article was that hypnosis was the glue for postmodern approaches to psychotherapy.
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Fri, 09 Dec 2016 08:12:45 GMT -08:00 http://www.scopemed.org/?mno=252193
Obsessions at Night: Dream Experiences, Emotional Attributes, and Personality Traits as Indicators of Sleep Problems http://www.scopemed.org/?mno=252192 2016-12-09T20-52-55Z
Source: Sleep and Hypnosis: A Journal of Clinical Neuroscience and Psychopathology
Calvin Kai-Ching Yu.
This study investigated the extent to which negative emotions, personality traits, and obsessive-compulsive distress modulate the relationship between sleep problems and dream experiences. The sample consisted of 610 upper secondary school students, whose subjective intensity of dream experiences, thematic dream content, obsessive-compulsive distress, personality traits, defensiveness, emotional qualities, and sleep disturbances were assessed using the Dream Intensity Scale, Dream Motif Scale, Obsessive-Compulsive Inventory-Revised, NEO Five-Factor Inventory, Marlowe-Crowne Social Desirability Scale, Beck Depression Inventory-II, Beck Anxiety Inventory, State-Trait Anger Expression Iventory-2, and Sleep Habits Questionnaire. The overall findings indicate that waking-life emotionality, personality traits, obsessive-compulsive distress, and other important factors for sleep quality – such as the ability to unwind one’s mind when retiring to sleep – moderate but do not mediate the relationship between disrupted sleep and dreaming. It seems, therefore, that dream experiences can serve as unique indicators of sleep problems.
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Fri, 09 Dec 2016 08:06:00 GMT -08:00 http://www.scopemed.org/?mno=252192
Sleep-Related Violence, Self-Mutilation, and Dissociative Experiences http://www.scopemed.org/?mno=252191 2016-12-09T20-52-55Z
Source: Sleep and Hypnosis: A Journal of Clinical Neuroscience and Psychopathology
Mehmet Yucel Agargun, Lutfullah Besiroglu, Mustafa Gulec, Adem Aydin, Yavuz Selvi.
Twenty-eight subjects with and 46 subjects without sleep-related violence (VBS) were evaluated regarding the presence of self-mutilative behaviors (SMBs). The subjects with and without VBS were compared using dissociative experiences scale (DES). The subjects with VBS had higher mean DES score and more frequent SMBs than those without VBS. These findings suggest that dissociation may be related to both daytime SMBs and violent behaviors during sleep in young population.
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Fri, 09 Dec 2016 08:04:07 GMT -08:00 http://www.scopemed.org/?mno=252191
Quality of nurse patient therapeutic communication and overall patient satisfaction during their hospitalization stay http://www.scopemed.org/?mno=220019 2016-12-09T20-52-55Z
Source: International Journal of Medical Science and Public Health
Sandhya Negi, Harleen Kaur, Grace M Singh.
Background: Effective communication is very important aspect in a nursing career. When patient admitted in the ward then therapeutic nurse patient relationship developed and if person is not mentally disturbed so that is very important nurses will properly communicate or needs to show a greater amount of interest to the information-giving process and decision making regarding the care of the patient. Objectives: The main aim of the research is to find the quality of nurse patient therapeutic communication and overall patient satisfaction during their hospitalization stay. Material and Method: An exploratory descriptive design was followed. A total of 110 patients were recruited by convenient sampling technique. Self developed Likert scale is used to assess the quality of nurse patient therapeutic communication and patient satisfaction. Result: Finding suggests that the most (81.8%) of the patient agreed that nurse was helpful and should concern on them, and 81% of the patient agreed that privacy and confidentiality was maintained. Only a few patients (4.5%) agreed that nurses were prompt in decision-making regarding their care.
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Fri, 09 Dec 2016 07:32:26 GMT -08:00 http://www.scopemed.org/?mno=220019
Retrospective case control study on typhoid and non-typhoid small bowel perforation http://www.scopemed.org/?mno=247828 2016-12-09T20-52-55Z
Source: International Journal of Research in Medical Sciences
Sandeep Mahapatra, Charan Panda.
Background: Out of several causes of small bowel perforations, Typhoid is the commonest cause in tropical countries claiming a higher morbidity and mortality profile. In Spite of conducting a good clinical examination and a battery of investigatory procedures, the etiology of perforation still remains obscure in a good number of cases. This retrospective case control study was conducted with an objective to evaluate the causes of small bowel perforation and to compare the surgical procedures and the outcomes in patients of typhoid and non-typhoid small bowel perforations. Methods: This study was based on hospital records for the last 3 years from April 2003 to April 2006. All the cases that were admitted with perforations had undergone a battery of tests to rule out the causes. 69 patients had one or the other test positive for typhoid (cases); the other causes of perforation were taken as control (n=43). Results: In typhoid perforations, although none of the operative procedures are clearly advantageous over the other, but anastomoses including the by-pass procedures are associated with more of complications wound dehiscence (p value 0.004), anastomotic leakage (p value 0.04), intra-abdominal collections (p value 0.009) with a longer hospital stay and hence to be avoided as practicable. Conclusions: Typhoid ileal perforation still has a poor prognosis with high morbidity and mortality. Late presentation, delayed surgery, multiple perforations, severe peritoneal contamination, and post-operative faecal fistula are factors that have an adverse effect on mortality. Most deaths occur during the early post-operative period, with survivors having a prolonged hospital stay.
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Fri, 09 Dec 2016 03:29:47 GMT -08:00 http://www.scopemed.org/?mno=247828
Solving the puzzle: what is behind our forefathers’ anti-inflammatory remedies? http://www.scopemed.org/?mno=244083 2016-12-09T20-52-55Z
Source: Journal of Intercultural Ethnopharmacology
Javier Rodriguez Villanueva, Jorge Martín Esteban, Laura Rodríguez Villanueva.
Inflammation is a ubiquitous host response in charge of restoring normal tissue structure and function but is a double-edged sword, as the uncontrolled or excessive process can lead to the injury of host cells, chronic inflammation, chronic diseases and also neoplastic transformation. Throughout history, a wide range of species have been claimed to have anti-inflammatory effects worldwide. Among them, Angelica sinensis, Tropaeolum majus, Castilleja tenuiflora, Biophytum umbraculum, to name just a few, have attracted the scientific and general public attention in the last years. Efforts have been made to assess their relevance through a scientific method. However, inflammation is a complex interdependent process, and phytomedicines are complex mixtures of compounds with multiple mechanisms of biological actions, which restricts systematic explanation. For this purpose, the omics techniques could prove extremely useful. They provide tools for interpreting and integrating results from both the classical medical tradition and modern science. As a result, the concept of network pharmacology applied to phytomedicines emerged. All of this is a step toward personalized therapy.
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Thu, 08 Dec 2016 13:39:47 GMT -08:00 http://www.scopemed.org/?mno=244083
The adjuvant use of calcium fructoborate and borax with etanercept in patients with rheumatoid arthritis: Pilot study http://www.scopemed.org/?mno=242586 2016-12-09T20-52-55Z
Source: Journal of Intercultural Ethnopharmacology
Saad Abdulrahman Hussain, Sattar Jabir Abood, Faiq Isho Gorial.
Objective: The present study was designed to evaluate the effects calcium fructoborate (CFB) and sodium tetraborate (NTB) as supplements in Iraqi patients with active RA maintained on Etanercept. Materials and Methods: A double blind randomized placebo-controlled clinical trial with 60 days treatment period was carried out at Baghdad Teaching Hospital, Medical City, Baghdad, Iraq. Eighty RA patients were randomized into 3 groups to receive either 220 mg/day calcium fructoborate, 55 mg/day sodium tetraborate in capsule dosage form (equivalent to 6 mg elemental Boron), or placebo formula once daily. Only 72 patients completed the study. All patients were clinically evaluated utilizing DAS28-ESR, SDAI-CRP and CDAI scores at baseline and at the end of the study. Venous blood was obtained at baseline and after 60 days, and utilized for the measurement of erythrocyte sedimentation rate (ESR), hemoglobin (Hb), in addition to evaluation of C-reactive protein (hsCRP), TNF-α, interleukin-1α (IL-1α) and IL-6. Results: After 60 days, both types of boron significantly improve the clinical scores, in association with significant decrease in the serum levels of ESR, hsCRP, IL-1α, IL-6, and TNF-α with remarkable superiority for CFB over NTB, compared to baseline and placebo-treated group. Conclusion: The use of boron, as adjuvant with etanercept, have potentiated therapeutic outcomes in RA patients, and may be a new strategy to improve treatment and avoid the problems associated with biologics utilized in RA treatment.
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Thu, 08 Dec 2016 13:39:15 GMT -08:00 http://www.scopemed.org/?mno=242586
Primary Adrenal Lymphoma Infiltrating in to Pancreas: A Rare Cause of Adrenomegaly http://www.scopemed.org/?mno=241844 2016-12-09T20-52-55Z
Source: Journal of Interdisciplinary Histopathology
Lovelesh Kumar Nigam, Kamal V Kanodia, Aruna V Vanikar, Rashmi D Patel, Kamlesh S Suthar, Syed J Rizvi.
Primary adrenal lymphoma is a rare entity and may be suspected in patients having bilateral adrenal masses, with/without lymphadenopathy, and with/without adrenal insufficiency. We report a rare case of a 45-year-old man who presented with pain in the abdomen, with no signs of adrenal insufficiency and bilateral adrenal masses on imaging. Light microscopy findings with immunohistochemistry and flow cytometry confirmed the diagnosis of diffuse large B-cell lymphoma. The patient was offered cyclophosphamide, adriamycin, vincristine, and prednisolone chemotherapy regimen and doing well till the last follow-up.
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Thu, 08 Dec 2016 13:15:31 GMT -08:00 http://www.scopemed.org/?mno=241844
The Significance of BerEp4 and Cytokeratin 19 Expressions in Epithelial Tumors of Kidney and Renal Pelvis http://www.scopemed.org/?mno=233151 2016-12-09T20-52-55Z
Source: Journal of Interdisciplinary Histopathology
Ayhan Ozcan, Ibrahim Yavan, Melih Kilinc, Sami Uguz, Sukru Ozaydin.
Objective: The differential diagnosis in the epithelial tumors of kidney and renal pelvis can be problematic due to their overlapping morphologic features. This is much more complicated in some conditions, such as renal oncocytoma (RO) vs chromophobe renal cell carcinoma (ChRCC) and renal cell carcinoma (RCC) vs urothelial carcinoma of renal pelvis (UC-RP). The purpose of this study was to assess potential contributions of BerEP4 and cytokeratin 19 (CK19) expressions in the differential diagnosis of these challenging cases. Methods: A total 57 cases consisted of 11 chromophobe (ChRCC), 18 clear cell (CCRCC), 12 papillary (PRCC), and 2 unclassified RCCs, 1 multilocular cystic renal cell neoplasm (MCRCN) with low malignant potential, 7 UC-RP, and 6 renal oncocytomas (RO) were stained against BerEp4 and CK19 antibodies using automated immunostainer. Results: All ROs demonstrated membranous BerEP4 expression, but no CK19 expression. Unlike ROs, most ChRCCs exhibited diffuse and strong CK19 expression, but no or focal and weak BerEP4 expression. This distinctive opposite expression pattern was highlighted in hybrid oncocytic chromophobe tumor (HOCT). CCRCCs showed highly variable expression patterns for both markers. PRCC type 1 tumors demonstrated diffuse and strong BerEp4 and CK19 expressions. PRCC type 2 exhibited BerEP4 and CK19 expressions, but their expressions were focal and weaker than for PRCC type 1. MCRCN demonstrated diffuse and strong BerEP4 expression, but no expression for CK19 unlike cystic CCRCC, which is strongly positive for both markers. Epithelioid cells in unclassified RCC showed strong CK19 and weak BerEP4 expression, whereas spindle cells in the tumor did not express CK19 and BerEp4 or exhibited scattered and weak expressions. UC-RP showed diffuse and strong CK19 expression, but no or scattered BerEP4expression was seen in the tumor. We also evaluated CK19 and BerEP4 expression in non-neoplastic adjacent kidney and renal pelvis. Conclusion: This study revealed that 1) BerEP4 and CK19 exhibit variable and distinctive immunoprofiles in epithelial tumors of kidney and renal pelvis, 2) an immunoprofile of BerEP4 (+)/CK19 (-) favors RO in contrast to an opposite profile for ChRCC, 3) The heterogeneous expressions of BerEP4 and CK19 in low grade RCC with eosinophilic cytoplasm favors HOCT, 4) PRCC type 1 strongly express both biomarkers, and 5) although RCC subtypes express CK19 in a variable proportion and intensity, diffuse and strong CK19 expression favors UC-RP.
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Thu, 08 Dec 2016 12:58:59 GMT -08:00 http://www.scopemed.org/?mno=233151
Pemphigus Vulgaris: A Comprehensive Presentation of the Desmosomal Adhesion Disrupting and Oral Blister Causing Multifactorial Autoimmune Disease http://www.scopemed.org/?mno=230852 2016-12-09T20-52-55Z
Source: Journal of Experimental and Integrative Medicine
Mandy Alhajj, Sathees B Chandra.
Abstract: Pemphigus Vulgaris (PV) is a blister causing autoimmune disease that is continually being studied because of its devastating symptomology and life-threatening effects on patients afflicted with the disease. There is a sense of urgency in finding better treatment options for PV patients and an even greater emphasis placed on diagnosing the disease in its earliest stages in order to improve its prognosis. The purpose of this paper is to provide a thorough presentation of pemphigus vulgaris, by discussing its genetics, prevalence, physiological mechanisms, pathogenesis, diagnostic and monitoring techniques, and treatments, in order to better equip clinicians with the current information on the disease and to prompt interest in future research on identifying potential environmental triggers.
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Thu, 08 Dec 2016 12:05:10 GMT -08:00 http://www.scopemed.org/?mno=230852
Alpha1-antitrypsin restores colonic epithelial permeability in irritable bowel syndrome with diarrhea http://www.scopemed.org/?mno=248897 2016-12-09T20-52-55Z
Source: Journal of Molecular Pathophysiology
Julien Boyer, Marie-Hélène Vivinus-Nébot, Valérie Verhasselt, Thierry Piche, Meri K Tulic.

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Thu, 08 Dec 2016 07:44:47 GMT -08:00 http://www.scopemed.org/?mno=248897
Consequences of the Fukushima nuclear accident with special reference to the perinatal mortality and abortion rate http://www.scopemed.org/?mno=246720 2016-12-09T20-52-55Z
Source: Journal of Environmental and Occupational Science
Sergei V. Jargin.
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Thu, 08 Dec 2016 06:18:37 GMT -08:00 http://www.scopemed.org/?mno=246720
Pattern of skin diseases in rural population: a cross sectional study at Medchal mandal, Rangareddy district, Telangana, India http://www.scopemed.org/?mno=250981 2016-12-09T20-52-55Z
Source: International Journal of Research in Medical Sciences
Janardhan Bommakanti, Pradeep Pendyala.
Background: The skin diseases are affected by various factors. The rural population is more vulnerable because of illiteracy. Therefore an attempt has been made to screen the population of five villages to know pattern of skin diseases. Aims of the study were to assess the prevalence of skin diseases, determine the pattern of skin diseases in the study population in rural community of Medchal mandal and compare previous studies so that inferences can be drawn for the benefit of society. Methods: The study was aimed to include the total population of 5930 consisting of 5 villages. The present study was carried out during a period of one and half year in 5 villages of Medchal mandal. The total population of all the 5 villages comprises of 7726, out of which 5930 persons participated in the present study. In all villages house to house survey was done. A complete dermatological assessment of the study population was done and findings were recorded on the standard study proforma. Results: The total number of 5930 persons was screened during the period of study. Among which 1172 (19.76%) persons were noted to have skin diseases. out of which 533 (45.48%) were males and 639 (54.52%) were females. The majority of population with skin disease was in the age group of 31-40 years with 289 cases (24.65%) and least in 71-80 age groups with 7 cases (0.59%). The prevalence of Non-infectious diseases (705 cases, 60.15%) was more than that of Infectious diseases (467 cases, 39.85%). Among non-infectious conditions Eczema / Allergy was the common disease followed by Pigmentary disorders other conditions like alopecia areata, seborrheic dermatitis and senile xerosis, Papulosquamous disorders, acne and acneiform dermatoses, polymorphous light eruptions and bite and stings, Eczemas followed by lichen simplex chronicus and allergic contact dermatitis. Among infectious conditions, bacterial infections were most common diseases followed by parasitic infestations, fungal infections and viral infections. Among Bacterial infections, secondary Pyodermas followed by folliculitis, impetigo and furunculosis. Based on occupation the majority of population was in the students followed by farmers, labour other than agriculture, housewives and petty business. Based on education, the majority of population was in the primary group (class 1 to 5) followed by secondary (class 6 to 8) and high school and above. Conclusions: Based on the outcome of this study, the common skin problems existing in this area are to be carefully looked for and health education regarding the hygiene, nutrition and healthy life styles is to be stressed for better standard of living by the rural population.
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Thu, 08 Dec 2016 04:35:11 GMT -08:00 http://www.scopemed.org/?mno=250981
Investigating the defensive medical practices of the physicians working in the city center of Malatya http://www.scopemed.org/?mno=244502 2016-12-09T20-52-55Z
Source: Medicine Science | International Medical Journal
Burak Mete, Erkay Nacar, Cigdem Tekin, Ertan Unver, Gulsen Gunes.
With this study, we aimed to determine the defensive medical practices of the physicians of different academic title and seniority, who are performing their duty in MalatyaAfter the approval from the ethical committee had been received, our study was conducted by performing surveys and face-to-face interviews with the practitioners, specialists, family practitioners and academicians working in the State and University hospitals as well as Private Hospitals in the city of Malatya. 234 physicians were asked to answer 19 questions regarding the defensive medical practices within the survey. 87% of the research sampling was reached. 176 (75,2%) of these physicians are male, whereas 58 (24,8%) of them are female. The mean age of the women who participated in the research is 38,9. It turned out that the physicians working in the state hospitals as well as private hospitals had referred to defensive medical practices more than those working in the university hospitals (P=0.026), and that the professors and associate professors had avoided the patients with the risk of filing a suit in temrs of medical malpractice less than the specialists and medical practitioners (p=0,003). In conclusion, it was determined that as the degree of professional experience, academic title and seniority in the physicians increased, the rate of defensive medical practices seemed to decrease.
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Thu, 08 Dec 2016 04:33:49 GMT -08:00 http://www.scopemed.org/?mno=244502
HIV/AIDS phobia leading to Schizophrenia like Psychosis in a benign cutaneous condition: Pearly Penile Papules. http://www.scopemed.org/?mno=252059 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Ghanshyam Verma, Dinesh Dutt Sharma, Ravi Sharma, Sandeep Kumar, G.R. Tegta, Ajeet Negi.
Pearly penile papules (PPP) are physiologic variant of the normal penis. They are asymptomatic skin colored smooth, measuring about 1-4 mm in diameter and occur in a single or double row on the corona of the glans commonly develop after puberty. Despite being asymptomatic these lesions can cause psychological distress in teenager and young adults considering it as serious concern or sexually transmitted disease (STD) of grave outcome. Many of the men with papules are concerned or worried by their presence and experience embarrassment leading to anxiety, depression and venereophobia. We herein present a case of PPP who developed schizophrenia like psychosis. To best of our knowledge such psychotic reaction secondary to PPP have not been described in the literature.
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Thu, 08 Dec 2016 03:11:04 GMT -08:00 http://www.scopemed.org/?mno=252059
Awareness of dental hygiene amongst the primary school children of low socio-economic strata http://www.scopemed.org/?mno=251226 2016-12-09T20-52-55Z
Source: International Journal of Contemporary Pediatrics
Ravi Kumar, Deepak Joshi.
Background: Childhood dental caries is a major health concern in children that continues to negatively affect the oral health. The condition if left untreated, can lead to disruption of growth and development of permanent teeth, pain, life threatening infections and expensive treatment. This study was done to assess the prevalence of the dental caries in primary school children and see their current level of awareness about dental hygiene practices. Methods: The present study was questionnaire-based cross sectional study. During the study 1000 school students of age 5-12 years were interviewed personally about the dental hygiene practices. The questionnaires were filled as per the responses given by them and after that basic dental and oral examination was carried out, to look for the condition of teeth, number of carious teeth in the mouth, number of restorations etc. Only one student was interviewed and examined at a time. After that he or she was provided with basic information to maintain good oral and dental hygiene. Results: The prevalence of dental caries is 31.6% and of these 4.43% had carries in more than 3 teeth. 60 children had at least one teeth restored. Only 16.3% children were totally aware of the dental hygiene. About 61.7% of them brush in morning, and only 30.4% for more than 2 minutes. 52.3% had never visited a dentist. Conclusions: Most of the children are not totally aware of the ways to maintain good oral hygiene and those who are aware are not practicing it. The role of parents is also very significant but nearly half of the parents do not guide their children for brushing and maintaining good oral hygiene. Regular dental check-ups by arranging dental camps in schools and educating the children and parents about oral hygiene will improve the situation.
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Thu, 08 Dec 2016 02:40:34 GMT -08:00 http://www.scopemed.org/?mno=251226
Assessment of nutritional status and its association with feeding practices in children under five years http://www.scopemed.org/?mno=250777 2016-12-09T20-52-55Z
Source: International Journal of Contemporary Pediatrics
Saba Syed, Biranchi Das.
Background: The level of child and maternal under nutrition remains unacceptable throughout the world. In India 48% of children are stunted, 20 per cent of children under five years of age suffer from wasting due to acute under nutrition. Methods: The present study was a cross-sectional study conducted on 211 children from 6 months - 6 years of age. Data collection included socio-demographic characteristics, anthropometric measurements and assessment of infant and young child feeding practices. Results: A total of 211 (128 females and 83 males) children were included in the study. The prevalence of underweight, stunting and wasting was observed to be 84 (39.81%), 99 (46.92%) and 47 (22.27%) respectively. Proportions of stunting and underweight was significantly more among children whose mothers reported inappropriate feeding practices as compared to their study counterparts. Conclusions: Under nutrition of sizeable magnitude is prevalent in children less than six years; as revealed by results of the present study. Past and current Infant and young child feeding practices were found to be significantly associated with under nutrition.
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Thu, 08 Dec 2016 02:35:38 GMT -08:00 http://www.scopemed.org/?mno=250777
Prediction of relapses in children with idiopathic steroid sensitive nephrotic syndrome: a retrospective study http://www.scopemed.org/?mno=248784 2016-12-09T20-52-55Z
Source: International Journal of Contemporary Pediatrics
Prasun B., Payas J., Sujaya M..
Background: Nephrotic syndrome is a chronic recurrent disease commonly affecting children belonging to the age group 1-10 years. The purpose of the study was to identify the factors at the onset of disease responsible for relapses in nephrotic syndrome. Methods: It was a retrospective observational study conducted in a tertiary care hospital in North India consisting of children aged 1-15 years diagnosed as nephrotic syndrome (1st episode) and followed for 12 months. Variables extracted from records (after January 2008) were age of presentation, days to remission, hematuria, and hypertension. Results: Out of 88 cases, 23 were frequent relapsers and 65 were infrequent relapsers. It was observed that cases remitting after 2 weeks have increased chances of frequent relapses. On stratification based on presence or absence of hematuria or hypertension, it was observed that both these variables predispose the patient towards frequent relapses. Conclusions: We concluded that variables like days to remission, haematuria and hypertension can fairly predict future relapses.
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Thu, 08 Dec 2016 02:29:25 GMT -08:00 http://www.scopemed.org/?mno=248784
Hydatid cyst of liver: different modalities of management and outcome http://www.scopemed.org/?mno=251634 2016-12-09T20-52-55Z
Source: International Surgery Journal
E. Muniswamy Gattu, Mehul Chopada.
Background: Echinococcosis affects the liver rather than other organs in 50-70 % of cases. While surgery is recognized as the only satisfactory method of treatment for liver echinococcosis (LE), many controversial results have been reported but total excision of the cyst alone or with part of the liver appear to be the most effective. This method is not always feasible, since it depends on the size and site of the cyst. Methods: The study information was collected using pre-tested semi structured questionnaire. The questionnaire was presented in the Department for critical review, following which necessary changes were made in the questionnaire. For all patients meticulous records was maintained regarding clinical features, family history, dietary habits and by performing various investigations. Results: Surgery was the mainstay of management. Out of 30 patients, 24 patients underwent complete pericystectomy (80%), 4 patients underwent incomplete pericystectomy (13.4%) and 3 patients had other procedures along with pericystectomy. Only 2 patients managed conservatively (6.7%). Conclusions: A variety of techniques, both radical and conservative, are used in the treatment of liver hydatid cyst.
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Thu, 08 Dec 2016 02:12:24 GMT -08:00 http://www.scopemed.org/?mno=251634
A study on profile of hydatid cyst of liver presented at a tertiary care hospital http://www.scopemed.org/?mno=251632 2016-12-09T20-52-55Z
Source: International Surgery Journal
E. Muniswamy Gattu, Saiyad Jameer Bhasha T..
Background: In many countries, hydatid disease is more prevalent in rural areas where there is a closer contact between people and dogs and various domestic animals which act as intermediate vectors. Methods: This study was carried out in the Department of Surgery at a tertiary care hospital. The patients attended surgical OPD and got admitted with hydatid cyst of Liver during the study period were the study subjects. Results: Majority of patients were farmers by occupation (76.7%) and some of them were house wives (13.3%) and Students (10%). The most common presenting complaint was pain abdomen (90%) followed by mass abdomen (30%). Conclusions: Effective interventions include regular de-worming of dogs and vaccinating dogs and other livestock, such as sheep, that also act as hosts for the tapeworm.
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Thu, 08 Dec 2016 02:07:26 GMT -08:00 http://www.scopemed.org/?mno=251632
Comparison of conventional suturing and tissue adhesive (2-octyl cyanoacrylate) for port site skin closure in laparoscopic surgeries http://www.scopemed.org/?mno=250885 2016-12-09T20-52-55Z
Source: International Surgery Journal
Samir Deolekar, Bhushankumar A. Thakur, Kushal Bairolia.
Background: Today there are numerous methods available for closure of wounds like tissue adhesives, staplers, adhesive tapes and obviously the age old conventional suturing, all of which have their own pros and cons. The aim was to study the complications and results of use of 2-octyl cyanoacrylate on wound healing and compare them without those of conventional suturing. Methods: Study comprised of 100 patients undergoing clean or clean contaminated elective laparoscopic surgery. After randomization 50 patients had their port site skin incision closed using 2-octyl cyanoacrylate. In the rest the port site skin incision was sutured using 3-0 polyamide. The scar was assessed using the stony brook scar evaluation scale. Results: The average Stony Brooke scar evaluation scale score was 4.2±1.03 (95% CI: 3.90 - 4.49) in the 2-octyl cyanoacrylate group and 3.12±1.04 (95% CI: 2.82-3.41) in the suturing group. The score was significantly higher in the 2-Octyl Cyanoacrylate group (p value≤ 0.001). 4 of 50 (8%) patients from the tissue adhesive group developed breaking of adhesive film. 8% and 4% developed wound infection from the suturing and 2-octyl cyanoacrylate group respectively(p value - 0.65). None of the patients showed any hypersensitivity to the product. Conclusions: 2-octyl cyanoacrylate is a safe and effective method for closure of skin incisions without any toxicity to the product. There is no difference in early complications such as breaking of film, wound dehiscence and wound infection when compared with conventional suturing. According to the Stony Brooke scar evaluation scale laparoscopic port sites closed using 2-octyl cyanoacrylate have better short term cosmetic appearance.
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Thu, 08 Dec 2016 02:02:48 GMT -08:00 http://www.scopemed.org/?mno=250885
A study of assessing knowledge, attitude and practice of pharmacovigilance among medical students of a South Indian teaching hospital http://www.scopemed.org/?mno=250761 2016-12-09T20-52-55Z
Source: International Journal of Basic & Clinical Pharmacology
Kulkarni Dhananjay, Esanakula Himasri.
Background: Pharmacovigilance is the science relating to detection, assessment, understanding and prevention of adverse drug reaction. The purpose is to improve patient safety in relation to use of medicines. It is estimated that only 6-10% of adverse drug reactions (ADRs) are reported worldwide. The underreporting of ADR is due to lack of adequate knowledge, attitude and practice among healthcare professionals towards ADR reporting. Health care professional like physicians, pharmacist and nurses have immense responsibility in reporting ADR. Therefore, the objective of this study was to evaluate the knowledge, attitude and practices (KAP) of undergraduate medical students towards pharmacovigilance. Methods: A cross-sectional KAP based questionnaires study was carried out in 100 undergraduate students of Konaseema Institute of Medical Sciences, Amalapuram. The response of KAP questionnaires were analyzed in percentage and tabular form. Results: Nearly 87% participants heard about pharmacovigilance, but only 65% know its need or purpose. 88% people feel that ADR reporting may improve patient safety. Less than half of the students know about Institutional ADR centre. 81% students have seen ADR but only 31% knew about ADR reporting form and surprisingly only 20% have reported ADR. More than 80% feels reporting ADR will increase patient safety. Conclusions: Participants have good knowledge about Pharmacovigilance but lacks in attitude and practice towards reporting ADR. Greater awareness of pharmacovigilance and incorporation of it in medical curriculum will further strengthen pharmacovigilance activity.
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Thu, 08 Dec 2016 01:13:31 GMT -08:00 http://www.scopemed.org/?mno=250761
Effect of vitamin A supplementation in category-I Pulmonary Tuberculosis patients in a Medical College in India: a rapid assessment analysis http://www.scopemed.org/?mno=249420 2016-12-09T20-52-55Z
Source: International Journal of Basic & Clinical Pharmacology
G. Sujatha, M. Dhanasekaran, Syed Shuja Qadri, S. Jeevithan.
Background: Tuberculosis is one of the major health problems affecting the global population causing immense morbidity and mortality. Studies have shown that a good antioxidant status of the body has immune protective role against tuberculosis and may be associated with a decreased risk of the disease and slower rate of progression. Objective of the study was planned to evaluate the beneficial effects of Vitamin A as add on therapy to the standard drug therapy in patients with sputum positive pulmonary tuberculosis. Methods: The study was done in a Tuberculosis clinic, Department of Internal Medicine, Stanley Medical College for duration of 6 months. All the newly diagnosed sputum positive pulmonary tuberculosis patients (18-55 years) attending the outpatient were taken for the study purpose. A Phase III, prospective, open, two arm parallel group, outpatient, randomized, active controlled study was done. Results: After two weeks of therapy, the number of patients with negative sputum smear was higher in the study group than the control group. Vitamin A supplementation resulted in an earlier elimination of tubercle bacilli from the sputum. Conclusions: This study shows that vitamin A as add on therapy to the existing standard therapy improves the clinical response and decreases the disease activity to a greater extent than with routine standard therapy alone.
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Thu, 08 Dec 2016 01:09:57 GMT -08:00 http://www.scopemed.org/?mno=249420
A comparative study of mebeverine and synbiotic combination in patients with diarrhoea predominant Irritable Bowel Syndrome in a Medical College in South India http://www.scopemed.org/?mno=248964 2016-12-09T20-52-55Z
Source: International Journal of Basic & Clinical Pharmacology
G. Sujatha, M. Dhanasekaran, Syed Shuja Qadri, S. Jeevithan.
Background: Irritable bowel syndrome (IBS) is a chronic, episodic functional gastrointestinal disorder characterized by abdominal pain / discomfort and altered bowel habits. Though it is considered as a functional disorder, the burden of the disease to the patients is very high and the quality of life becomes miserable. Currently available IBS therapies are mainly symptom oriented and have limited efficacy. Various studies had done so far which provide a clear rationale for the use of Synbiotic in this disorder. The objective of the study includes, this study was planned to compare the efficacy of Mebeverine + Synbiotic combination with Mebeverine and Synbiotic monotherapy in patients with diarrhoea predominant irritable bowel syndrome. Methods: The study was done in Department of Medical Gastroenterology, Rajiv Gandhi Government Hospital, Chennai for duration of one year. Patients with Irritable Bowel Syndrome (diarrhea predominant type), diagnosed within 1 year and attending outpatient department were taken. A randomized, Phase III, prospective, interventional, open label, , outpatient, comparative study design was done. A total of 60 patients divided into 3 groups were finally selected for the study purpose. Results: Twelve weeks after completion of active drug therapy, the Mebeverine + Synbiotic combination improved all the symptoms of IBS except abdominal pain. Further it was evident that combination therapy had significant remission in stool frequency and consistency when compared with other groups. Conclusions: Combination of Mebeverine + Synbiotic is more effective in improving most of the troublesome symptoms in patients with diarrhea predominant irritable bowel syndrome than other therapies and also in maintaining remission, in terms of frequency and consistency of stools.
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Thu, 08 Dec 2016 00:23:06 GMT -08:00 http://www.scopemed.org/?mno=248964
Synovial Chondromatosis of the Knee: Management with Arthroscope - Assisted Synovectomy and Removal of Loose Bodies: A Case Report. http://www.scopemed.org/?mno=252030 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Ajay Surwade, Amit Chaudhary, Yashwant Mahale.
Synovial chondromatosis (also called synovial osteochondromatosis) is a rare, benign condition that involves the synovium, which is the thin layer of tissue that lines joints. Although this type of tumor does not spread to other parts of the body, it can cause severe damage to the joint and lead to osteoarthritis. Early treatment is important to relieve painful symptoms and prevent further damage. We remove loose bodies and synovium through Arthroscope- Assisted Synovectomy and removal of Loose Bodies. This procedure is safe, have minimal blood loss and surgical dissection was minimal.
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Wed, 07 Dec 2016 23:06:01 GMT -08:00 http://www.scopemed.org/?mno=252030
Bilateral Lower Limb Paralysis Rehabilitation: A Case Study of Muscle Action Exercises Approach. http://www.scopemed.org/?mno=252029 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Francis Kofi Nutakor, Monday Omoniyi Moses.
Background: Bilateral lower limb paralysis is a stressful medical symptom limiting activities of the nerves which controls leg muscles. Although, the option of exercise therapy in the treatment of bilateral lower limb paralysis has been recommended, its usage in Kumasi, Ghana, has not been well reported. This study therefore is a case report on the treatment of bilateral lower limb paralysis with muscle action exercise workout supported with literature review. Case Description: A 74-year old woman was admitted the clinical department of the Ejura Government hospital, Ejura, Ashanti with body temperature of 36.5°Ϲ, blood pressure of 110/65 mmHg and body weight of 98kg. The patient was diagnosed of Lumbago, Pruritic papular skin lesion, motor neuron lesion, unavailable dorsalis pedis on palpation and very faint on auscultation. She was placed on medical therapy with slight improvement and latter subjected to a 21-day muscle action exercise workout. Results: Age reduced to 72kg and full bilateral lower limb mobility showed a clinically significant restoration in the fifth week. Dosalis pedis’s skill improved to 68 bpm regarded to be better than medical therapy only, body temperature upturned 37.4°Ϲ while blood pressure became normal at 120/65 mmHg. Conclusion: Bilateral lower limb paralysis is a degenerative disorder that should be treated medically in conjunction with exercise therapy. Rehabilitation centers are encouraged see exercise inclusion in the promotion of holistic recovery, emotional stability and social re-integration of patients as obligatory.
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Wed, 07 Dec 2016 23:04:29 GMT -08:00 http://www.scopemed.org/?mno=252029
Benign Cervical Teratoma in an Adult: A Rare Neck Swelling. http://www.scopemed.org/?mno=252028 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
P.S. Mulay, S.A.Deshpande, Mansi Gulati, Manisha Ahuja, Amita Patil, Rohit Mangal.
Cervical teratomas are extremely rare germ cell tumors that occur in the neck. Most of these tumours occur in infants and neonates and are almost always benign. In extremely rare cases, cervical teratomas occur in adults and are usually malignant. Cervical teratomas are differentiated into primary thyroid or extrathyroid based on the relationship of the tumour with the thyroid gland. Surgery is the primary modality of treatment as malignant transformation occurs during adulthood. The diagnosis of malignancy is based on histopathologic examination. Adjuvant chemotherapy is indicated when malignancy is confirmed. We report a case of benign cervical extrathyroidteratoma in an adult.
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Wed, 07 Dec 2016 23:02:43 GMT -08:00 http://www.scopemed.org/?mno=252028
The Brain Eating Amoeba! An Unusual Case Report. http://www.scopemed.org/?mno=252027 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Sanchari Saha, Reeta Dhar, Smriti Dewan, ShaliniYadav, Urshlla Kaul.
Acanthamoeba is a eukaryotic protist that occurs world-wide and can potentially cause infections in humans and other animals. Acanthamoeba cause the insidious and mostly fatal disease, granulomatous amoebic encephalitis (GAE), particularly in immunocompromised or otherwise debilitated individuals. Acanthamoeba meningoencephalitis, also known as GAE is a rare, but nearly always fatal disease, caused by infection with Acanthamoeba species. The organism enters the nasal cavity when water contaminated with amoebae is aspirated. Subsequently, it invades the central nervous system through the olfactory neuroepithelium, disseminates via haematogenous spread, and migrates into CNS at the blood brain barrier, and causes a fatal infection. We report a case of granulomatous amoebic meningoencephalitis (GAE)in an eleven year old male child, who was immunocompromised, a known case of AML (Acute Myeloid Leukaemia-type II), on chemotherapy, presenting with fever, headache, altered sensorium and seizures, with positive meningeal signs, where on wet mount cytology of CSF suggested Acanthamoeba.
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Wed, 07 Dec 2016 23:01:21 GMT -08:00 http://www.scopemed.org/?mno=252027
A Rare Case Report on Chronic Neutrophilic Leukemia with Review of Literature. http://www.scopemed.org/?mno=252026 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Priyanka Gupta, Kishore Shaw, Raka Hota, Sukumar Chakravarty.
Chronic neutrophilic leukemia (CNL) is a very rare myeloproliferative neoplasm (MPN) of elderly characterized by sustained neutophilic leucocytosis (>25000/cumm). Considering its rare entity, herein we report a case of CNL in an 80year old man who presented with dyspnoea, pleurisy and PUO. Persistent neutrophilic leukocytosis in a case of PUO in an elderly patient similar to this case can lead to a mistaken underdiagnosis. Suspicion is therefore required, to diagnose a case as CNL, if a patient presents with sustained neutrophilic leukocytosis without any underlying cause, not responding to higher antibiotics.
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Wed, 07 Dec 2016 23:00:06 GMT -08:00 http://www.scopemed.org/?mno=252026
Bowel Prolapse and Strangulation Following Induced Abortion: A Case Report and Review of Literature. http://www.scopemed.org/?mno=252025 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Olaogun Julius Gbenga, Adeojo Idowu Pius, Ige Joshua Taye, Briggs Praise Kess, Ajayi Omolola Oluwabunmi.
Bowel prolapse and strangulation is an uncommon and life threatening complication of induced abortion. It is commonly seen in countries where abortions are performed by untrained personnel and unskilled medical practitioners. A case is reported of a 25-year old woman with missed abortion at 5months gestation who had instrumental evacuation complicated by hemoperitoneum, bowel prolapse and strangulation. Patient subsequently had exploratory laparotomy, bowel resection and primary anastomosis with good postoperative outcome.
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Wed, 07 Dec 2016 22:58:15 GMT -08:00 http://www.scopemed.org/?mno=252025
Successful Spinal Anesthesia in a Case of Achondroplastic Parturient for Cesarean Section: Case Report. http://www.scopemed.org/?mno=252024 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Madhanmohan, Rekha Bayer, Mamta Damor, Basant Dindor.
Achondroplastic pregnant patients almost invariably lead to caesarean section due to cephalo-pelvic disproportion. We report a twenty year old short stature primigravida in labour taken for elective caesarean section for cephalopelvic disproportion. On physical examination she was short statured with height of 110 cm and weight of 37 kg. She had large head with frontal bossing and short limb. Examination of spine showed reduced intervertebral space. All clinical examinations were supportive of a diagnosis of Achondroplasia. Spinal anaesthesia was planned. 25G quinke spinal needle was inserted in L4-L5 subarachnoid space with paramedian approach successfully in second attempt. Local anesthetic bupivacaine and fentanyl were given intrathecally. Adequate motor and sensory blockade achieved and surgery went uneventful. Patient was stable intra and post-operatively.
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Wed, 07 Dec 2016 22:57:01 GMT -08:00 http://www.scopemed.org/?mno=252024
Acute Hemodialysis in Pregnancy - AKI with Live Fetus in Utero - A Series of Five Cases. http://www.scopemed.org/?mno=252022 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Manjusha Yadla, Bhavya Dasara.
Hemodialysis following the delivery or death of fetus is more common scenario in management of pregnancy related AKI unlike hemodialysis in antenatal period with live fetus in utero which is a challenging task as two lives are to be salvaged. Herein, we report the challenges we faced and the outcomes 5 cases of AKI in pregnancy with live fetus in situ that underwent hemodialysis.
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Wed, 07 Dec 2016 22:54:10 GMT -08:00 http://www.scopemed.org/?mno=252022
Systemic Lupus Erythematosus Patient Presenting With Acute Pulmonary Edema as the Initial Hospital Presentation. http://www.scopemed.org/?mno=252021 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Aparna Patange, Shivaraj Afzalpurkar, Piyush Prajapati, Omkar Patil.
Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that occurs more commonly in women in the age group between 16 to 60 years. SLE most commonly affects skin but heart and cardiopulmonary circulation can also be significantly affected. [1] Acute non cardiogenic pulmonary edema is a rare initial presentation of SLE. [2]
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Wed, 07 Dec 2016 22:53:05 GMT -08:00 http://www.scopemed.org/?mno=252021
Reversible Cortical Blindness with Bilateral Ptosis: A Rare Feature of Hepatic Encephalopathy. A Diagnosis Rarely Thought! http://www.scopemed.org/?mno=252019 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Sangita Deepak Kamath, Ballamudi Srinivas Rao.
Hepatic encephalopathy (HE) reflects a spectrum of neuropsychiatric abnormalities seen in patients with liver dysfunction and is diagnosed after the exclusion of other known causes of cerebral dysfunction. Rarely, visual cortex may be affected in patients with liver disease and cortical blindness (CB) may occur. It may be the presenting feature of HE and may be mistaken for cerebral stroke, if it other features of HE are not present. It is usually transient and resolves with efficient treatment of encephalopathy. We report a case of transient CB with bilateral ptosis in a young patient of hepatic encephalopathy due to hepatitis B virus related chronic liver disease in view of its rarity and unusual presentation.
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Wed, 07 Dec 2016 22:51:30 GMT -08:00 http://www.scopemed.org/?mno=252019
A Rare Case of CNS Vasculitis Presenting as Cerebral Ischaemia in Systemic Lupus Erythematosus. http://www.scopemed.org/?mno=252017 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Sabarish Mahalingam, P. Z. Wadia, Mithram Wadia.
Systemic lupus erythematosus is an autoimmune disease characterized by multisystemic involvement which may affect every organ in the body without any specificity. Neuropsychiatric Systemic Lupus involvement [NPSLE] is a complex neurological disorder characterized by neuropsychological dysfunction may range from mild diffuse to acute life threatening events. In the pathology of Neuropsychiatric lupus, vasculopathy due to infarcts and hemorrhages are often observed, whereas vasculitis is rare. Neuropsychiatric symptoms often occur in the first year, but are rarely the presenting symptoms of the disease. We reported a case of Neuropsychiatric Lupus in a twenty years aged female presenting with convulsion and blurring of vision which is primarily due to vasculitis.
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Wed, 07 Dec 2016 22:50:13 GMT -08:00 http://www.scopemed.org/?mno=252017
Aberrant Thyroid in Glenoid Cavity of Scapula: A Rare Case Report. http://www.scopemed.org/?mno=252016 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Rajeev Sen, Shilpi Bhargava, Richa Panwar, Namita Bhutani, Sucheta, Rajat Gauba.
Ectopic thyroid refers to presence of thyroid tissue in another region apart from its normal anatomic localization, that is, anterolateral to the second to fourth tracheal cartilage. Its prevalence accounts for 1 case per 300 persons and 1 in 4-8 patients with symptomatic thyroid disease. Fine Needle Aspiration Cytology (FNAC) and histopathological examination with immunohistochemistry (IHC) provide confirmatory diagnosis of ectopic thyroid and also helps to differentiate between normal thyroid tissue and metastatic well-differentiated thyroid carcinoma. Herein, we report a rare entity of aberrant thyroid tissue which came out to be normal thyroid tissue on histopathological examination.
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Wed, 07 Dec 2016 22:49:00 GMT -08:00 http://www.scopemed.org/?mno=252016
Progressive Systemic Sclerosis: A Case Report and Review of Literature. http://www.scopemed.org/?mno=252014 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Nirupa Thomas, Thomas Priya, Rekha Krishna Pillai, Ramakrishnan Bindhu P.
Systemic sclerosis (SSc) is a collagen disorder, characterized by vasomotor disturbances, fibrosis, and atrophy of skin, subcutaneous tissue, muscles, and internal organs (alimentary tract, lungs, heart, kidney, CNS) with associated immunologic disturbances. Dense collagen is deposited in the tissues of the body in extraordinary amounts. Systemic sclerosis can affect the facial and oral structures as well and can present as diagnostic dilemma. This paper reports a case of systemic sclerosis in a 24 year old female patient with hard, shiny skin, depigmentations, mouse facies, resorption of terminal phalanges, claw like hands, microstomia, reduced mouth opening, and fibrosis of oral mucosa. Orthopantomogram showed generalized PDL space widening and resorption of condyle. The characteristic presentations in this case enabled us to establish the diagnosis of progressive systemic sclerosis.
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Wed, 07 Dec 2016 22:47:33 GMT -08:00 http://www.scopemed.org/?mno=252014
Radicular Cyst with Epithelial Metaplastic Changes: A Case Report. http://www.scopemed.org/?mno=252013 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Usha Hegde, Alekya Akasapu.
Radicular cyst is the most common cystic lesion in the jaws, which is always associated with non-vital tooth. It arises from the epithelial residues within the periodontal ligament as a result of inflammation. The occurrence of ciliated, vacuolated, or mucous cells in odontogenic lesions is rare, but a well-recognised phenomenon. They are more commonly seen in maxillary lesions (21%) than mandibular lesions (14%). Metaplastic changes into these forms are found in the epithelial lining of radicular cysts, commonly on the surface layer. The pathological basis for this transition is poorly understood. We hereby present a case of radicular cyst with unusual changes in the epithelial lining, in a 29 year old female patient.
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Wed, 07 Dec 2016 22:46:14 GMT -08:00 http://www.scopemed.org/?mno=252013
Maternal Mortality Burden: The Influence of Socio-Cultural Factors. http://www.scopemed.org/?mno=252011 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Florence Femi Odekunle.
Background: Maternal mortality is one of the major health problems confronting Nigeria and other resource-poor countries Objective: This study aimed to examine principally whether and how socio-cultural factors affect maternal mortality in Nigeria. Methods: A comprehensive literature search was conducted on two electronic databases: Scopus and Pro Quest Health and Medical Complete. Results: Available evidence indicated that there were many non-biomedical factors that predispose pregnant women to a higher risk of maternal mortality. Socio-culturally, harmful traditional beliefs and practices; early marriage, high parity and female illiteracy contribute to the high burden of maternal deaths in Nigeria. Conclusion: Maternal mortality reduction needs action beyond prevention and treatment of biomedical causes; it needs the modification of the socio-cultural contexts that contribute to high maternal mortality in Nigeria. They are difficult to change but indispensable to maternal health. Hence, high maternal death must be addressed within the socio-cultural context of different Nigerian regions.
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Wed, 07 Dec 2016 22:44:58 GMT -08:00 http://www.scopemed.org/?mno=252011
Genomics in Personalized Medicine. http://www.scopemed.org/?mno=252010 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Florence Femi Odekunle.
Background: Genomics is the study of the complete genetic material of an organism. Personalized medicine is a type of medicine that uses data and information about an individual’s genes to prevent, diagnose, and treat a disease. The main goal of this paper was to review the applications and roles of genomics in personalized medicine. Materials and Methods: A literature search was conducted on Pub Med and Google scholar electronic databases. Results: One of the most important areas that involve the application of genomics is pharmacogenomics, which is the leading technology for personalized medicine. Genomics plays significant roles in personalized medicine by making genomic data and information available, which eventually guides decision-making to choose the most appropriate and most effective treatments, thereby reducing drug adverse reactions. Genomics also plays a vital role in personalized medicine by reducing risk associated with multiple medications (polypharmacy). Conclusion: Genomics makes personalized medicine a reality. Personalized medicine is dependent on scientific advances in understanding of how an individual’s unique genetic and molecular profile place one at risk of some kind of diseases. More importantly, scientific discoveries increase our ability to predict which medications will be effective and safe for individual patients, and which medications will not be.
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Wed, 07 Dec 2016 22:43:47 GMT -08:00 http://www.scopemed.org/?mno=252010
Congenital Adrenal Hyperplasia in Saudi Arabia. http://www.scopemed.org/?mno=252009 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Nasir A.M. Al Jurayyan.
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder resulting from a deficiency of one of the enzymes necessary for cortisol synthesis. As a result, decreased cortisol synthesis, increased adrenocorticotropin (ACTH) hormone via negative feedback system and over production of the hormones prior to the enzymatic defect. It is not a rare disorder in Saudi Arabia, where more than 90% of cases are due to 21-hydroxylase deficiency. Variable clinical forms ranging from the severe classical CAH, associated with complete loss of enzyme function to the milder non-classical forms (NCAH) where encounter. This review presents an overview of the various types of CAH in Saudi Arabia, particularly the most common type 21-hydroxylase deficiency, highlighting its epidemiology, clinical presentation, diagnosis and management.
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Wed, 07 Dec 2016 22:42:34 GMT -08:00 http://www.scopemed.org/?mno=252009
Diagnostic Modalities for HIV Distal Symmetrical Peripheral Neuropathy: A Review. http://www.scopemed.org/?mno=252008 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Alagoma Iyagba, Arthur Onwuchekwa.
Objective: To review the current diagnostic modalities for HIV-distal symmetrical polyneuropathy (HIV-DSPN), the commonest neurological complication of HIV. Materials and Methods: A MEDLINE search of the English-language literature using a combination of words (HIV, distal symmetrical, polyneuropathy, diagnosis) to identify original studies, consensus statements, and reviews published in the past three decades. Emphasis was on diagnosis of HIV distal symmetrical polyneuropathy, the most common form Results: The various modalities available for the diagnosis of HIV-DSPN. Conclusion: Early screening and diagnosis of distal symmetrical polyneuropathy would facilitate institution of new treatments or modification of antiretroviral therapies. This would in the long-term decrease disease-related morbidity by improving the patient’s quality of life.
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Wed, 07 Dec 2016 22:41:23 GMT -08:00 http://www.scopemed.org/?mno=252008
Non-Communicable Diseases during Disaster - Time to Take Action. http://www.scopemed.org/?mno=252007 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Surekha A, Suguna Anbazhagan.
Non-Communicable Diseases (NCDs) are now recognised as a real and growing threat to population health and development; Developing countries are often disproportionately burdened by both NCDs and disasters in comparison to higher income countries. While disasters can exacerbate existing NCDs, suboptimal management during and after a disaster not only has immediate health effects, but can also have lasting social and health ramifications. Greater advocacy and awareness surrounding NCDs and emergencies is vital.
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Wed, 07 Dec 2016 22:40:01 GMT -08:00 http://www.scopemed.org/?mno=252007
Virtual Reality and Pain Management. http://www.scopemed.org/?mno=252006 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Dilek Karaman.
Invasive procedures, which are commonly used in diagnosis and treatment of diseases, are known as painful procedures. Cognitive behavioral implementations in pain management are used as nonpharmacological method. In the recent years, developed virtual reality, thanks to the advancement of computer technology, falls into many different methods which are used in these implementations. Virtual reality makes people to feel that they are in a different environment by using human machine interfaces. Patients give their attentions to the environment that they see and process of pain signal operations slows down and pain perceived less. In this essay, activity of virtual reality on pain in invasive procedures will be examined.
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Wed, 07 Dec 2016 22:38:44 GMT -08:00 http://www.scopemed.org/?mno=252006
Diplomatic Epic of P63-An Immunohistochemical Marker and its Role in Perplex Neoplasms - A Review. http://www.scopemed.org/?mno=252005 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
R.Priyadharshini, Pandurangan Harikrishnan, Sowmiya Murali.
P63 is basically a stem cell marker. It belongs to p53 protein family which comprises of transcription factors p53, p63, p73. P63 also possesses two isoforms which are interestingly with opposing characters. Its complexity remains unrevealed with helps in maintenance of genetic stability of germ cells, mechanisms of p63 behaves both monogenic as well as tumor suppressor of its various isoforms. P53 family regulates many vital biological process including cell differentiation, proliferation and cell death / apoptosis. Phylogenetic analysis revealed that p53 family was originated from p63 / p73-like ancestral gene early in metazoan evolution.P63 shows expression in various neoplasms, it is typically used as stem cell marker. Various evidences show over expression of p63 in squamous cell carcinoma. Unlike other exocrine glands salivary gland possess typical myoepithelial cells that have the ability to transform as neoplastic cell. Tumors of salivary glands are quiet interesting, based on studies done in population of atomic- bomb survivors in Hiroshima and Nagasaki, radiation seems to provoke salivary gland neoplasms. In this review we are going to overlook anthropogenesis of p63 and its role in various neoplasms.
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Wed, 07 Dec 2016 22:37:12 GMT -08:00 http://www.scopemed.org/?mno=252005
Zinc and Insulin Resistance in Pregnancy Complicated with Gestational Diabetes. http://www.scopemed.org/?mno=252004 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Mariana P. Genova, Bisera Atanasova, Katia Todorova-Ananieva, M. Velisarova, J. Hristova, Kamen Tzatchev.
Metabolism of certain trace elements, as zinc, was altered in gestational diabetes mellitus (GDM) with insulin resistance (IR) as a key factor in the pathophysiology. The aim of the present study was to investigate the relation between IR in GDM and plasma, and erythrocyte levels of zinc. Totally 35 pregnant women with normal glucose tolerance (NGT) and 37 pregnants with GDM were included. Zinc was measured by flame atomic absorption spectrophotometry. Positive correlations between erythrocyte zinc, plasma zinc and fasting blood glucose (FBG), insulin levels and HOMA-IR were found for healthy pregnant group. The correlations between zinc in erythrocytes and FBG, insulin and HOMA-IR were higher than those between plasma zinc and the same parameters with statistical difference for HOMA-IR (P
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Wed, 07 Dec 2016 22:35:10 GMT -08:00 http://www.scopemed.org/?mno=252004
Gender Differentials in Health Expectancy in Rural Areas of Nagaland. http://www.scopemed.org/?mno=252003 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Seikh Faruk Ahmed.
Health status is an important determinant of economic and social development of a population. Life expectancy, an indicator of measuring health status of a population, has been increasing worldwide over the years. Longer life does not necessarily mean healthier life. Health expectancy, an important indicator of measuring the quality of life lived by a population. The objective of this study is to examine whether gender differentials in health expectancy exists in the rural areas of Nagaland- a hilly state in the north east India. Age specific proportions of persons afflicted by disease were collected from 5404 individuals belonging to 1150 households using a cross sectional survey conducted in May- July, 2011 in 23 villages of Kohima and Dimapur districts of Nagaland. Sullivan’s method was used to estimate the health expectancies for both sexes in the rural areas of Nagaland. The health expectancies at birth for males (females) in the rural areas of Nagaland were found to be 50.64 (52.27) years. A clear gender differential has been observed with females having an advantage in health expectancies compared to males in all ages in the rural areas of Nagaland.
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Wed, 07 Dec 2016 22:33:27 GMT -08:00 http://www.scopemed.org/?mno=252003
Techniques for Brief Strengths Based Social Case Work. http://www.scopemed.org/?mno=252002 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Sudeep Jacob Joseph, A. Thirumoorthy, K. Sekar.
Background: Depression is a debilitating common mental disorder that interferes with a person’s functionality and quality of life. The realm of social interventions in the area of depression has been explored in a few settings but is yet to be validated for clinical practice. Almost all of these interventions focuses and deals with the problems that the person with depression faces. The strengths perspective is a dramatic departure from conventional social work practice. A quick review of the existing literature on social work reveals that almost all recent textbooks make a reference to the strengths perspective. However, they lack empirical and practical content. Materials and Methods: This is part of a doctoral thesis. 9 Key Informants were interviewed and a card sorting method was used to arrive at 3 comprehensive techniques that can be used as strengths based social case work interventions among persons with depressive disorders. These were pilot tested with 6 persons with depression and outcome variables of symptom severity, quality of life and functionality were assessed pre and post intervention. Results and Discussion: The three techniques include River of Life, Social Network Mapping, and Step Ladder. These techniques have been described in detail and their practical implications discussed. The pilot test shows positive trends and requires further study to arrive at definite conclusions. Conclusion: This paper introduces and expounds three apparently effective, practical techniques that can be taught to social work students in the area of Mental Health.
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Wed, 07 Dec 2016 22:31:22 GMT -08:00 http://www.scopemed.org/?mno=252002
Dynamics Changes of Proteolytic Balance in Blood Plasma under Experimental Chemical Burns of Esophageal Development in Rats. http://www.scopemed.org/?mno=252001 2016-12-09T20-52-55Z
Source: International Journal of Health Sciences and Research (IJHSR)
Ishchuk T.V., Koval T.V., Savchuk O.M., Raetska Ya.B., Ostapchenko L.I..
Background: Proteinases control all metabolic processes involved in neurotransmitter receptor signalling in coordinating the process of fibrinolysis, hemocoagulation, activation of the complement system. In critical conditions there is an infringement of dynamic equilibrium between the proteases and their inhibitors, which is an important link in the pathogenesis of many diseases. In literature there is no data on patterns of change proteases and their inhibitors in the bloodstream after esophagus burning injuries. These experimental data would allow to assess the nature of reparation process in case of esophagus burning, and accordingly develop effective methods of proteolysis targeted correction. Aim: To investigate features of proteolytic enzymes system and their inhibitors in the pathogenesis post burning process. Methods: Chemical burns in animals were experimentally modeled in the following way: alkaline esophageal burn was caused by 20% NaOH and acid esophageal burn was caused by 30% CCl3COOH. The total proteolytic activity analyzed by method of caseinolytic activity with modifications. The level of α1-AT and α2-MG were determined using the method Nartykova. Results: The result of the research it's shown that the development of alkali burn there was observed increased activity of MMP and serine proteases on 15th and 21st day against a background of increased levels of α2-MG. However when modelling acid burn, decrease of proteolytic enzymes on 15th and 21st day and increased α1-AT level during experiment was observed. Conclusion: As a result of the research there were showed different dynamics of changes in alkaline and acid burns of the esophagus. Thus, the results may indicate inflammation at the latest experiment terms in modelling the esophagus alkali burns.
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Wed, 07 Dec 2016 22:21:01 GMT -08:00 http://www.scopemed.org/?mno=252001