ScopeMed - RSShttp://www.scopemed.orgScopeMed RSSen-us Copyright © 2011 ScopeMed All rights reserved. ScopeMedhttp://www.scopemed.org/img/logo-scopemed-ttk.gifhttp://www.scopemed.org 2015-05-27T22-51-41Z A study on sequelae of prolonged dystocia evaluated during laparohysterotomy in small ruminants http://www.scopemed.org/?mno=188654 2015-05-27T22-51-42Z
Source: International Journal of Livestock Research
DEVI PRASAD VADDADI, Sreenu Makkena, Venkata Suresh Kumar Rayadurgam, Chandra Sekhara Rao Tammineedi.
Abstract: The cost of laparohysterotomy in small ruminants was found to be less than that estimated for large ruminants. Animals which had prolonged dystocia showed rupture of uterus and post maturity changes of the placenta. Animals in which rolling was done to relieve torsion, showed utero-omental ecchymosis. Avascular necrosis, meconial contamination of dam’s abdomen, intra abdominal hemorrhages etc were the other findings. Posterior presentation was found to be associated with only 1.39% of the total cases (n=72). The time lapse between the onset of labour and time of surgery greatly influenced the success and postoperative fertility rates.
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Wed, 27 May 2015 08:22:51 GMT -08:00 http://www.scopemed.org/?mno=188654
Use of N-acetylcysteine in obsessive-compulsive and related disorders http://www.scopemed.org/?mno=163297 2015-05-27T22-51-42Z
Source: Bulletin of Clinical Psychopharmacology
Nursu çakın memik, Özlem yıldız gündoğdu, Ümit Tural.
Information on the use of N-acetylcysteine (NAC) in neuropsychiatric disorders has increased in recent publications. Although there are positive reports on the use of NAC in obsessivecompulsive and related disorders (OCRD), such data have not yet been validated. This article aims to review the research, case series and case reports that have been published about the use of NAC in OCRD. Research papers and case reports on the use of NAC in OCRD published within the last five years have been reviewed using the search engines of “Pubmed” and “Medline Central” databases. The search was performed by matching the terms “obsessive-compulsive disorder (OCD)”, “trichotillomania (TTM)”, “nail biting”, “skin picking”, “hoarding disorder”, and “body dysmorphic disorder” with “N-acetylcysteine”. The search identified 4 papers on TTM, 3 papers on nail biting behavior, 1 paper on OCD and 1 paper on skin-picking behavior. Three of these papers were double-blind, placebo-controlled studies and four were case reports/series. The results of 2 papers out of the 7 that we reviewed showed that there was no difference between NAC and placebo, while 5 papers reported that the response to the NAC therapy was positive. We did not find any papers on the use of NAC in either hoarding disorder or body dysmorphic disorder. NAC is thought to be a promising psychopharmacologic agent in OCD, which is defined under OCRD due to its common etiology, similar clinical features and similar response to treatment, as well as in TTM, skin picking and nail biting. The effectiveness of glutamatergic modulators on repetitive behaviors or OCD has increased interest in NAC. Although there are a few studies in the area, many research projects are being planned, with some already in progress (www.clinicaltrials. gov), a fact that emphasizes the importance of NAC in OCRD treatment. NAC has been used in a broad spectrum of conditions such as paracetamol intoxication, doxorubicin cardiotoxicity, ischemia-reperfusion-induced injury of the myocardium, acute respiratory distress syndrome, bronchitis, chemotherapy intoxication and heavy metal intoxication. In recent years, there has been an increase in the number of studies exploring the use of NAC in neuropsychiatric disorders such as schizophrenia, autism, bipolar disorder and OCRD. In this review, we have seen that the results of studies assessing the efficacy of NAC in psychiatric disorders are promising; however, there is a need for further studies to evaluate its mechanism of action, appropriate dose range and duration of treatment
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Wed, 27 May 2015 06:44:10 GMT -08:00 http://www.scopemed.org/?mno=163297
PERFORMANCE OF TURKEY POULTS AS INFLUENCED BY ORGANIC ACIDS SUPPLEMENTATION IN THE DIETS http://www.scopemed.org/?mno=189214 2015-05-27T22-51-42Z
Source: International Journal of Livestock Research
Michael Chikezie Ugwuene, Dozie Ndubisi Onunkwo.
Abstract A fifty-six days study was conducted to evaluate the influence of organic acid on performance of turkey poults. Four (4) experimental diets (T1,T2, T3,T4) were formulated in which 0.25% of formic, acetic and lactic acid were added to T2,T3 and T4, T1 serving as control diet. Seventy two (72) turkey poults were randomly allotted to the four (4) treatment diets. Each treatment was replicated three (3) times with each replicate having six (6) poults in Completely Randomized Design. Feed and water were offered ad-libitum. There was no significant difference (P>0.05) in all the growth parameters. However, T2 has the highest value in profit. The values of dry matter (69.50), ether extract (19.00), nitrogen free extract (70.70) and ash (24.00) of the turkey meat on T2 were significantly higher (P
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Wed, 27 May 2015 02:26:33 GMT -08:00 http://www.scopemed.org/?mno=189214
SURGICAL MANAGEMENT OF PERVIOUS URACHUS IN FOUR ONGOLE FEMALE CALVES http://www.scopemed.org/?mno=189229 2015-05-27T22-51-42Z
Source: International Journal of Livestock Research
Palli Ravi Kumar, Pentyala Vidya Sagar, Mulinti Raghunath.
Four female Ongole calves of age less than one week were presented with a history of dribbling of urine from the umbilicus besides from the vulva. The condition diagnosed as pervious urachus, is a neonatal continuation from the bladder that fails to close after birth and corrected surgically under general anaesthesia. The calves showed normal urination from vulva and showed uneventful recovery.
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Wed, 27 May 2015 02:23:17 GMT -08:00 http://www.scopemed.org/?mno=189229
Consideration of cerebral venous thrombosis as a cause of delirium in psychiatry clinics http://www.scopemed.org/?mno=38329 2015-05-27T22-51-42Z
Source: Bulletin of Clinical Psychopharmacology
Betul Ozdilek, Selma Bozkurt Zincir, Fusun Mayda Domac.
venous infarct due to cerebral venous thrombosis might present only with psychiatric symptoms, such as delirium, psychosis, depression, anxiety, irritability, lack of interest, personality change, apathy/abulia or cognitive deterioration. This condition might be difficult to diagnose on clinical grounds alone. Radiological studies are crucial for establishing a definitive diagnosis. Non-invasive magnetic resonance imaging combined with magnetic resonance venography with and without contrast is the most sensitive diagnostic technique for demonstrating venous infarct and dural sinus thrombosis. This study presents three patients with respective diagnoses of recurrent depression, bipolar disorder, and schizophrenia. Subsequently, each patient developed new-onset agitation, psychosis symptoms, and delirium.
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Wed, 27 May 2015 02:22:08 GMT -08:00 http://www.scopemed.org/?mno=38329
Propolis Induced Mania with Psychotic Features: A Case Report http://www.scopemed.org/?mno=162382 2015-05-27T22-51-42Z
Source: Bulletin of Clinical Psychopharmacology
Halil Ozcan, Tuba Ulkevan.

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Wed, 27 May 2015 02:07:24 GMT -08:00 http://www.scopemed.org/?mno=162382
Correlation between olfactory bulb volume and chronic depression: a magnetic resonance imaging study http://www.scopemed.org/?mno=174864 2015-05-27T22-51-42Z
Source: Bulletin of Clinical Psychopharmacology
Ali Irfan Gul, Kamran Sari, Mahmut Ozkiris, Reha Aydin, Gulnihal Gokce Simsek, Halil Ibrahim Serin, Levent Saydam.
Objective: Olfactory dysfunction can be seen secondary to various diseases, such as sinonasal disease, infections of the upper respiratory tract, head trauma, and neurodegenerative diseases. A small number of recent studies have focused on olfactory dysfunction in different neuropsychiatric disorders. This study aimed to investigate olfactory bulb (OB) volume in patients with chronic major depression, as diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). In particular, we investigated patients treated with selective serotonin reuptake inhibitors (SSRIs). To the best of our knowledge, this is the first study to investigate this subject. Methods: Participants included 31 outpatients (17 females and 14 males) with chronic major depression recruited from the University School of Medicine and Public Hospital psychiatry outpatient clinic between March 1 and August 31, 2013. Participants were examined using the Beck Depression Inventory (BDI). All patients were receiving treatment with a single SSRI. The BDI was also administered to a control group of 31 healthy volunteers (16 females, 15 males). All participants were recruited over the telephone after the study design was finalized. Additionally, both groups underwent a magnetic resonance imaging (MRI) scan with a 1.5-Tesla MRI system. Volumes of the right and left OBs were determined using MRI scans of the head and a standardised protocol for OB examination. Results: OB volumes were calculated separately for the depressed and the control groups. MRI measurements revealed significantly smaller olfactory bulb volume in patients with chronic major depression as compared to the control group. Furthermore, we detected a negative correlation between BDI score and olfactory bulb volume. Conclusions: Olfactory bulb volumes are notably smaller in patients with chronic major depression treated only with SSRIs (fluoxetine, sertraline, citalopram, escitalopram, paroxetine). To our knowledge, this is the first study to reveal reduced olfactory bulb volume in patients with chronic major depression. This study has demonstrated a negative correlation between OB volume and elevated depression scores.
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Wed, 27 May 2015 01:24:45 GMT -08:00 http://www.scopemed.org/?mno=174864
Psychiatrists’ attitudes toward psychopharmacologic treatments during pregnancy and lactation periods: a survey study http://www.scopemed.org/?mno=46264 2015-05-27T22-51-42Z
Source: Bulletin of Clinical Psychopharmacology
Ahmet Bulent Yazici, Esra Yazici, Nazan Aydin, Ayla Tanriverdi.
Objective: Pregnancy and lactation are risk periods that make women susceptible to psychiatric illnesses. As well as side effects and teratogenic effects of drug utilization, negative effects of untreated psychiatric illnesses on fetus and mother may be issues of concern. Management of pregnancy and lactation periods may become complicated by a relapse of a psychiatric illness or by using a drug with unexpected harm affecting mother or baby. Mental health professionals are commonly confronted with patients who ask for advice during such times. In determining the course of treatment, the attitudes of mental health professionals are as important as are the attitudes of patients. This study has been conducted to evaluate attitudes and personal opinions of psychiatrists. Methods: An Internet survey was designed to ask questions about the tendency to use pharmacotherapy, electroconvulsive therapy (ECT), or psychotherapy, cessation or lowering the dosage of medicines, and the personal principles of psychiatrists during pregnancy and lactation. The relationship between academic degrees and professed knowledge levels of psychiatrists about management of treatments of pregnant and lactating women and personal comments are also evaluated. Of those asked, 246 psychiatrists answered the mails and 213 online-surveys were completed. Results: Of the respondents, 22.2% were assistant psychiatrists, 50.9% were specialist psychiatrist, 6.6% were assistant professors, 9% were associate professors, and 11.3% were full professors. The results showed that avoidance of starting drug utilization, terminating an ongoing drug treatment, seeking alternatives to drug treatment, transition to ECT treatment and consulting a higher center were significantly more common in pregnancy than during the lactation period (p
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Wed, 27 May 2015 01:21:07 GMT -08:00 http://www.scopemed.org/?mno=46264
EVALUATION AND COMPARISON OF VARIOUS PRESCRIPTION SPECIFICATIONS AND SLOT DISTORTION OF PRE-ADJUSTED EDGEWISE BRACKETS MANUFACTURED BY DIFFERENT COMPANIES AVAILABLE IN INDIA http://www.scopemed.org/?mno=189849 2015-05-27T22-51-42Z
Source: International Journal of Current Research and Review
Eshan Awasthi, Narendra Sharma, Sunita Shrivastav, R.H. Kamble.
Objective: To assess and evaluate the tip, torque, slot size & slot distortion of maxillary central incisor, maxillary lateral incisor & maxillary canine brackets from commercially available bracket systems (Agile Mini Brackets- 3M series, Mini series- American Orthodontics, Mini Gem series- Dento Smile, Fine Series Brackets - Galaxy Orthodontics, Centrino Mini brackets- Libral trader, Orthox Organizers) in the 0.022-inch dimension. Material & method: The sample consisted of three brackets each (maxillary central incisor, lateral incisor & canine) of all the companies the tip, torque & slot dimension of which were measured in the 0.022-inch dimension. Images were obtained using stereomicroscope & measurements were taken after operator calibration using AU|TOCAD software 2012, and a digital readout was produced. Results: Results indicated that none of the companies showed exact values of tip & torque however 3M Agile Mini series showed values nearest to normal whereas Orthox Organizers showed most inaccurate values. For slot dimension American Orthodontics Mini series showed most accurate values whereas Orthox Organizers showed most inaccurate values. All the companies showed oversized slot except Dento Smile Mini Gem series which showed undersized slot. Slot distortion was found maximum in Orthox Organizer & least in American Orthodontics Mini series. Conclusion: Inaccuracy in slot dimension, inbuilt tip and torque of the pre-adjusted brackets can affect the final position of teeth in the arch with an added need of wire bending to achieve desired results.
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Wed, 27 May 2015 00:51:56 GMT -08:00 http://www.scopemed.org/?mno=189849
AWARENESS AND ASSSESSMENT OF ORAL HYGEINE AND PERIODONTAL STATUS AMONG THE CONSTRUCTION WORKERS IN A J HOSPITAL CAMPUS, MANGALORE http://www.scopemed.org/?mno=189848 2015-05-27T22-51-42Z
Source: International Journal of Current Research and Review
Bipina P., Manjushree Kadam, Nasila Mohammed, Anjali Jain.
Background: The health of construction workers goes ignored because of their stressful working conditions, busy schedules and poor economic conditions. The need for dental care should be emphasized among these workers. Limited literature on their attitude towards oral health, their awareness, habits and behavior among these construction workers incited us to assess the preventive oral health care awareness and oral hygiene practices among the construction workers in A.J hospital, campus, Mangalore. Materials and methods: Total of 136 systemically healthy construction workers were selected for the study. A questionnaire was administered by examiner. The study proforma consisted of demographic data and data related to oral hygiene habits and practices. Oral Hygiene Index-Simplified and Community Periodontal Index and Treatment Needs indices were used to record oral hygiene status and periodontal status respectively. Chi-square test was used to determine the association between the variables. P value < 0.05 were selected to denote statistical significance. Results: Majority of the workers brushed once daily and had adverse habits, poor oral hygiene status and periodontitis associated with bleeding gums and halitosis. Most of the workers had a dental visit only in problem. Conclusion: The community should be provided with dental health education by giving more importance in oral hygiene maintenance, habit counseling and regular dental visits.
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Wed, 27 May 2015 00:48:44 GMT -08:00 http://www.scopemed.org/?mno=189848
SPINAL ANAESTHESIA IN DOWN’S SYNDROME- A CASE REPORT http://www.scopemed.org/?mno=189846 2015-05-27T22-51-42Z
Source: International Journal of Current Research and Review
V. Bhavani, Deepak Paulose.
Patients with Down’s syndrome presents with unique set of problems while taking up for surgeries. Anaesthesiologists should have a clear knowledge of pathophysiology and potential problems that can happen intraoperatively and should be equipped to tackle these problems.
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Wed, 27 May 2015 00:43:32 GMT -08:00 http://www.scopemed.org/?mno=189846
STUDY OF SACRUM AND ITS IMPORTANCE IN EPIDURAL BLOCK http://www.scopemed.org/?mno=189845 2015-05-27T22-51-42Z
Source: International Journal of Current Research and Review
P. Sasikala, Arunkumar S. Bilodi.
Aim of study: The objective of study is on sacrum for sacral hiatus due to its importance in epidural anesthesia. Place of study: This study was done in the department of anatomy at Velammal medical college hospital and research institute, Madurai, India. Period of study: This study was done during the month of February 2015. Materials and methods: 30 dry unknown human sacra from department of anatomy constituted the materials for the present study. Their dimensions were measured and sacral index were calculated for each sacrum. Shape, composition of sacrum, shape of sacral hiatus, level of sacral hiatus and curvature of the sacrum were noted down. Conclusion: Anatomical knowledge of sacral hiatus will be of great help in administering caudal analgesia through sacral hiatus.
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Wed, 27 May 2015 00:40:23 GMT -08:00 http://www.scopemed.org/?mno=189845
THREE DIMENSIONAL EVALUATION OF CONDYLAR HEAD INCLINATION WITH RESPECT TO RAMUS AMONG POST PUBERTAL CLASS II PATTERNS http://www.scopemed.org/?mno=189844 2015-05-27T22-51-42Z
Source: International Journal of Current Research and Review
Abhilasha Goyal, R. H. Kamble, Sunita Shrivastav, Narendra Sharma.
Objective: To assess the condylar head inclination with respect to ramus in Angle’s Class II division 1 and division 2 skeletal patterns using Digital Volume Tomography. Material and method: The sample consisted of 45 post pubertal patients who were divided on the basis of clinical and cephalometric analysis into three groups - skeletal Class I, Class II division 1 and Class II division 2. The selected cases underwent Digital Volume Tomography and the images obtained were used to assess condylar head inclination, mediolateral and anteroposterior thickness of the condylar head on right and left sides for all the three groups. ANOVA, Least significance difference and Paired student’s t test were done. Results: The Class II division 2 group showed significantly more anteriorly angulated condyles as compared to those of Class II division 1 and Class I groups on both right and left sides. Class II division 1 group showed significantly smaller mediolateral dimension as compared to Class I and Class II division 2 groups. The anteroposterior dimension was not significantly different in all three groups studied. Conclusion: There exists a variation in the condylar morphology in the various skeletal malocclusions examined. The individuals with Class II division 2 malocclusion had a tendency towards having more anteriorly angulated condyles. Also the mediolateral dimension of condylar head of individuals with Class II division 1 malocclusion is smaller than Class II division 2 and Class I malocclusions.
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Wed, 27 May 2015 00:36:42 GMT -08:00 http://www.scopemed.org/?mno=189844
CAFFEINE EXTRACTION AND CHARACTERIZATION http://www.scopemed.org/?mno=189843 2015-05-27T22-51-42Z
Source: International Journal of Current Research and Review
Pradeep S., G. N. Rameshaiah, Hadagali Ashoka.
Caffeineextracted and characterised from tea (black) leaves and coffee beans. Isolation was done by liquid-liquid extraction using di-chloromethane as an extracting agent. This extraction was done in four steps: steeping, evaporation, liquid-liquid extraction and recrystallization. The recrystallization was done using anhydrous sodium sulphate.The technique used for purity analysis and characterisation were: High performance liquid chromatography, Differential scanning calorimeter, Fourier transform infrared spectroscopyand Melting point. First, the analysis was done using melting point analysis. The melting point of caffeine extracted from coffee beans and tea leaves was found to be 238°C. The absorption bands were compared with that available in literature and were found to be similar. Further, the purity check was done using High performance liquid chromatography method.Effective characterization of caffeine was achieved by determining Infrared spectrum, and employing a melting point apparatus and differential scanning calorimeter. The purity showed that the results that the extracted coffee was 90% pure. Further improvements in extraction efficiency will increase the yield and minimize wastage.
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Wed, 27 May 2015 00:33:07 GMT -08:00 http://www.scopemed.org/?mno=189843
DIVERSITY AND DISTRIBUTION OF AQUATIC INSECTS IN SOTHUPARAI RESERVOIR, AT PERIYAKULAM, THENI DISTRICT, TAMILNADU, INDIA http://www.scopemed.org/?mno=189841 2015-05-27T22-51-42Z
Source: International Journal of Current Research and Review
Medona Mary R., Nirmala T., M. R. Delphine Rose.
The present study deals with the diversity and distribution of aquatic insects from Sothuparai Reservoir. It is located at the foothills of the Western Ghats. The aquatic entamofauna were sampled systematically and randomly using standard protocols. The aquatic insects act as an indicator species to monitor the environmental pollution. Ephemeropteran were most diverse and its presence indicative of good water quality. The abundance of organic pollution tolerant Baetis were found in downstream, nearer to human settlements. The physico chemical variations of water taken into account for the study were found to be influencing the distribution of aquatic insects. It is suggested that routine bio monitoring of the reservoir using aquatic insect indicators will facilitate better conservation and management.
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Wed, 27 May 2015 00:29:45 GMT -08:00 http://www.scopemed.org/?mno=189841
KINETICS AND EQUILIBRIUM STUDIES OF THE ADSORPTION OF PHENOL AND METHYLENE BLUE ONTO COLA NUT SHELL BASED ACTIVATED CARBON http://www.scopemed.org/?mno=189839 2015-05-27T22-51-42Z
Source: International Journal of Current Research and Review
Lekene Ngouateu R. B., Kouoh Sone P M. A., Ndi Nsami J., Kouotou D., Belibi Belibi P. D., Ketcha Mbadcam J..
The aim of this work was to study the removal of methylene blue (MB) and phenol from aqueous solution using powder activated carbon prepared from cola nut shells chemically activated with KOH solution. The effect of contact time, adsorbent dose, pH and initial concentration has been studied using batch adsorption method. Given the base line for the results, the percentage removal of MB and phenol were 98.19 % and 61.81 % respectively. The maximum adsorption of MB and phenol occur at pH 8 and 6. Also the quantity adsorbed decreases with the adsorbent dose for both adsorbates. The quantity adsorbed of MB increases with increased in initial concentration whereas reverse result was observed with phenol. The adsorption equilibrium data were confronted to Langmuir, Freundlich, Tempkin and Dubinin-Kaganer-Radushkevich isotherms models. The Langmuir model describes better the adsorption with maximum monolayer adsorption capacities of 65.79 mg.g-1 and 6.22 mg.g-1 for MB and phenol respectively. The kinetics of methylene blue and phenol adsorption were also discussed using pseudo-first-order, pseudo-second-order, Elovich, mass transfer and intra-particle diffusion models. The adsorption process follows the pseudosecond- order and mass transfer kinetic models respectively for methylene blue and phenol owing to their high correlation coefficient. This study shows that the prepared activated carbon can be used as low cost alternative adsorbent for removal of both phenol and MB.
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Wed, 27 May 2015 00:26:10 GMT -08:00 http://www.scopemed.org/?mno=189839
"Traumatic bilateral anterior glenohumeral dislocation .Should unsupervised training at local gym be allowed?" http://www.scopemed.org/?mno=186221 2015-05-27T22-51-42Z
Source: Progress in Orthopedic Science
Hayat Ahmad Khan, Younis Kamal, Mohammad Ashraf Khan, Naseemul Gani, Munir Farooq, Adnan Zahoor.
The wide range of motion provided by the shoulder complex allows the glenohumeral joint to be used as a stable fulcrum for placing the upper extremity at various positions in three-dimensional space. A consequence of this flexibility, however, is the propensity for the joint to become unstable. Shoulder joint mostly dislocates anteriorly but the bilateral dislocations are of rare occurance. Most of these are posterior. Bilateral anterior dislocations are of rare occurrence and only few cases are reported in English literature which are usually associated with fractures. We report this case of bilateral anterior shoulder dislocation due to hyperextension injury caused due to unsupervised open weight bench pressing without any associated fracture. Closed reduction was done under sedation uneventfully. Unsupervised training at the local gyms should be discouraged and proper equipment should be sought for these fitness training centres to prevent such injuries
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Tue, 26 May 2015 14:54:49 GMT -08:00 http://www.scopemed.org/?mno=186221
In-vitro anthelmintic efficacy of some Kashmiri medicinal plants against Haemonchus contortus http://www.scopemed.org/?mno=188794 2015-05-27T22-51-42Z
Source: International Journal of Livestock Research
Shahjahan Alam, Tarun Kumar Sarkar, Irfan Ali Shah, Imtiyaz Reshi, Mazar Ali Shah.
A study was conducted to test the in-vitro anthelmintic efficacy of crude aqueous extracts (CAE) and crude ethanolic extracts (CEE) of the aerial parts of A. absinthium, Artemisia maritima Linn (Moorin), Acorus calamus Linn (Vai), Nepeta cataria Linn and root of Picrorhiza kurroa Royle ex Benth against Haemonchus contortus. The worm motility inhibition assay was utilized in order to investigate the direct effects of plant extracts on the survival of the adult Haemonchus contortus of Sheep under in -vitro conditions. Significant anthelmintic effects of CAE and CEE on live adult Haemonchus contortus worms (P < 0.05) were observed in terms of the paralysis and/or death of the worms at different hours post-treatment (PT), however, CEE were more efficacious than CAE. In conclusion, Artemisia absinthium Linn (Tethwan) showed highest in-vitro anthelmintic efficacy and can be utilized for further in-vivo study.
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Tue, 26 May 2015 06:59:56 GMT -08:00 http://www.scopemed.org/?mno=188794
AMELIORATING ROLE OF JAMBOLAN OF CAPECITABINE INDUCED TESTICULAR DAMAGE OF RATS http://www.scopemed.org/?mno=189785 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Heba A. El-Ghawet, Abdelalim A. Gadallah.
Capecitabine (Xeloda, Roche) is a pro- anticancer drug, that is enzymatically converted to 5-fluorouracil in the body. The present work aimed to evaluate the ameliorated role of the jambolan fruit-extract against testicular damage induced by capecitabine. Twenty male Wistar albino rats (Rattus norvegicus) weighing approximately 120 g were used during experimentation. Animals were divided into four groups; control (saline-treated), Jambolan-treatment (400 mg/kg of fruit extract), capicitabine-treatment (40 mg /Kg BW for 30 days), and capicitabine and jambolan-treatment. Daily oral treatments were carried out for 30 days. At the end of experimentation period, the animals were sacrificed and their testis were incised and processed for histopathological investigation, comet and flow cytometric analysis for apoptosis. The present findings revealed that the drug-treatment possessed dramatic testicular damage in the form of focal disorganization of the seminiferous tubules with almost missing of sperm, comparatively decreased spermatogenic cells, sloughing and degeneration of spermatogenic cells and interstitial oedematous lesions. Flow cytometric analysis showed apparent increase of apoptic M1 spermatogenic and ovarian cells. Comet assay revealed apparent increase of detached spermatogenic cells. Jambolan-treatment ameliorated the pathological picture and decreased the incidence of apoptosis. Finally, the authors concluded that the jambolan-treatment with its higher content of antioxidants resolute the toxicological aspects of the anticancer drugs.
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Tue, 26 May 2015 06:36:35 GMT -08:00 http://www.scopemed.org/?mno=189785
Would Anti-Hypertensive Treatment be a Risk Factor for National Health Budget of Turkey in 2023? http://www.scopemed.org/?mno=185064 2015-05-27T22-51-42Z
Source: Medicine Science | International Medical Journal
Mehmet Bilgehan Pektas, Mustafa Aldemir, Ayhan Pektas, Onder Akci, Ismet Dogan.
This study aims to predict the prevalence of hypertension and the cost of anti-hypertensive treatment in future by analyzing the adults diagnosed with hypertension and the drugs prescribed for their treatment in Turkey during a period of five years. This study reviews data related to the patients diagnosed with hypertension amongst the individuals registered within the Medula database of the Turkish Social Insurance Institution from 2009 to 2013. A significant and gradual increase was specified in the prevalence of hypertension during the study period. The number of female patients was significantly higher than the number of male patients over the passing years. The number of anti-hypertensive drug boxes consumed was significantly increased during the study period. Surprisingly, the number of anti-hypertensive boxes annually consumed by the hypertensive patients remained statistically similar between 2009 and 2013. A significant increase was noted in the prescription of angiotensin II receptor blockers, beta blockers, and angiotensin converting enzyme inhibitors during the study period. The cost of anti-hypertensive treatment was found to decrease by 36.7% during the study period. The economical measures currently adopted for drug pricing are successful but health policies developed for the prevention of hypertension are inadequate.
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Tue, 26 May 2015 06:29:34 GMT -08:00 http://www.scopemed.org/?mno=185064
TEMPORAL AND SPATIAL EXPRESSION PATTERNS OF SAPR IN THE FRUIT FLY DROSOPHILA MELANOGASTER (DIPTERA: DROSOPHILIDAE) http://www.scopemed.org/?mno=189783 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Samar E. El-Kholy, Wesam S. Meshrif.
Temporal and spatial expression patterns of saposin-related protein receptor (SapR) were determined in Drosophila melanogaster using GAL4/UAS system. The first step was to generate Drosophila line expressing SapR conjugated with GAL4. Then, the resulting line was crossed to UAS-GFP line. The GFP expression pattern in the first generation was monitored and analyzed in details. The results revealed that SapR was expressed in salivary glands, trachea, Malpighian tubule and CNS of larvae, compound eyes, oenocytes and the base of tactile sensillae of adults. GFP was also detected in intestine of both larval and adult stages.
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Tue, 26 May 2015 06:00:48 GMT -08:00 http://www.scopemed.org/?mno=189783
OXIDATIVE STRESS IN LIVER AND WHITE MUSCLES OF NILE TILAPIA AS RESPONSES TO POLLUTED AREA IN THE NILE RIVER http://www.scopemed.org/?mno=189781 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Mohamed A. M. Hegazi, Somya Z. Abd El Haleim, Mahmoud M. S. Sirdah, Saleh N. Mwafy.
Oxidative stress in liver and white muscles of Nile tilapia, Oeochromis niloticus captured in Rosetta branch of Nile River at Kafr El-Zayat area, Al-Gharbiyah Governorate, Egypt was studied. The toxic effects of water in this area that, receive a lot of sewage and other industrial pollutants discharge, on the antioxidant system of Nile tilapia (62.4 ± 6.9 g) were investigated. Water samples were analyzed for physicochemical parameters including pH, turbidity, total dissolved solids, ammonia, nitrite and nitrate. The activities of antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S-transferase (GST), glutathione reductase (GR) and the level of lipid peroxidation (LPO) in liver and white muscles were assayed. The examined physicochemical parameters found to be in excess than the maximum standard limits in water samples of the examined areas. The increase was more detectable during autumn and winter than other seasons. The alterations in the physicochemical parameters of water are consistent with the alteration reported in the enzymes activity of SOD, GST, GR, and GPx, as well as LPO, concentration which increased significantly (P ≤ 0.05) as compared to the control. However, the increase was more detectable during autumn and winter than in summer and spring seasons. The physicochemical parameters considered as the most important principles in the identification of the nature, quality and type of the water and/or any aquatic system. Antioxidant enzymes and the oxidative stress biomarkers lipid peroxidation considered as the most important biomarkers used to identify polluted marine sites. This can be taken as a useful biomarker for environmental managers in investigating the exposure of fish to contaminated freshwaters. This study could be beneficial for ecotoxicological researches in freshwaters as it provides data about antioxidant system response for fish exposed to different water pollutants.
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Tue, 26 May 2015 05:52:07 GMT -08:00 http://www.scopemed.org/?mno=189781
AMELIORATING ROLE OF JAMBOLAN OF CAPECITABINE INDUCED TESTICULAR DAMAGE OF RATS http://www.scopemed.org/?mno=189780 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Heba A. El-Ghawet Abdelalim A. Gadallah.
Capecitabine (Xeloda, Roche) is a pro- anticancer drug, that is enzymatically converted to 5-fluorouracil in the body. The present work aimed to evaluate the ameliorated role of the jambolan fruit-extract against testicular damage induced by capecitabine. Twenty male Wistar albino rats (Rattus norvegicus) weighing approximately 120 g were used during experimentation. Animals were divided into four groups; control (saline-treated), Jambolan-treatment (400 mg/kg of fruit extract), capicitabine-treatment (40 mg /Kg BW for 30 days), and capicitabine and jambolan-treatment. Daily oral treatments were carried out for 30 days. At the end of experimentation period, the animals were sacrificed and their testis were incised and processed for histopathological investigation, comet and flow cytometric analysis for apoptosis. The present findings revealed that the drug-treatment possessed dramatic testicular damage in the form of focal disorganization of the seminiferous tubules with almost missing of sperm, comparatively decreased spermatogenic cells, sloughing and degeneration of spermatogenic cells and interstitial oedematous lesions. Flow cytometric analysis showed apparent increase of apoptic M1 spermatogenic and ovarian cells. Comet assay revealed apparent increase of detached spermatogenic cells. Jambolan-treatment ameliorated the pathological picture and decreased the incidence of apoptosis. Finally, the authors concluded that the jambolan-treatment with its higher content of antioxidants resolute the toxicological aspects of the anticancer drugs.
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Tue, 26 May 2015 05:49:27 GMT -08:00 http://www.scopemed.org/?mno=189780
DIFFERENTIATION OF EMBRYONIC STEM CELLS TOWARDS THE CHONDROGENIC AND OSTEOGENIC LINEAGE CAN BE ENHANCED BY MAGNETIC FIELD http://www.scopemed.org/?mno=189771 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Fouad A. Abou–Zaid **Henrry Sauer Ibraheem K. EL-Shourbagy *Khaled M. Omar Mohamed M. Bekhite.
Pluripotent Embryonic stem (ES) cells have the capability to differentiate to various cell types and may represent an alternative cell source for the treatment of cartilage defects. In the present study, the effects of different intensities and types of magnetic fields (MFs) were tested on chondrocyte differentiation from ES cells. The results indicated that differentiation of ES cells toward the chondrogenic and osteogenic lineage could be enhanced by low MFs exposure of 1 mT. ES cell-derived embryoid bodies (EBs) exposed to MFs showed an increase in chondrogenic nodule areas consisting of chondroprogenitor mesenchymal cells, indicating stimulation towards chondroblasts differentiation. Osteogenic differentiation and mineralization were confirmed by immunofluorescence staining and RT-PCR showing osteoblast specific osteocalcin expression. Findings of this study have potentially important implications for cartilage tissue engineering, since they enable the increase in differentiated cell numbers needed for the development of functional cartilaginous tissue in vitro suitable for implantation.
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Tue, 26 May 2015 04:28:32 GMT -08:00 http://www.scopemed.org/?mno=189771
CD4 and CD8 T cell responsiveness in chronic hepatitis C patients with or without schistosomiasis http://www.scopemed.org/?mno=189769 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
S.A. Sakr, ., G. Badra, A. EL-Kenawy, A. El-Bendary.
The combined viral hepatitis and schistosomiasis incidence was found to be increasing; however scarce studies are available which investigated the influence of Schistosoma mansoni on the HCV specific immune response. This study included four groups: Group 1 included 23 patients infected with chronic HCV, Group 2 included 10 patients infected with Schistosoma mansoni, Group 3 included 21 patients infected with chronic HCV and Schistosoma mansoni, Group 4 included 10 healthy controls. HCV-specific CD4+ and CD8+ T cell responses were measured by flow cytometery in all groups and correlated with PCR level. The infected patients with chronic HCV alone had stronger CD4+ T cell response than did coinfected patients also the coinfected patients had the lowest percent of CD8+ T cell, and significantly higher HCV-RNA titers. An inverse relationship between virus load and CD4+ T cell responses were found. Schistosomiasis is one of the mechanisms which lead to viral persistence through downregulation of immune response and accelerate liver damage in HCV patients.
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Tue, 26 May 2015 04:26:23 GMT -08:00 http://www.scopemed.org/?mno=189769
THE ROLE OF VITAMIN C IN AMELIORATING PARAQUAT EFFECTS ON LUNG HISTOLOGY, CHROMOSOMES AND BRAIN AND LIVER ENZYMES OF MICE http://www.scopemed.org/?mno=189768 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Samaa M. Bakr Noura F. Ghanem Nahed E. Hassan*.
The role of vitamin C in ameliorating paraquat effects on the chromosomes, brain and liver enzymes and lung histological structure in mice were studied. Ten animals, in the third group, were considered as control group of mice and exposed under similar conditions with application of saline solution. The histopatho-logical examination of mice lungs administ-rated orally with paraquat revealed severe degree of bronchopneumonia with numerous foci of granulomatous reactions. The lungs of mice treated with paraquat and vitamin C showed little amounts of edematous fluid in alveoli associated with areas of slightly dilated, emphysematous alveoli and mild lymphocyte infiltration. Administration of paraquat for 4 weeks increased the percentage of chromo-somal aberrations if compared with the non-treated control. The mitotic activity in treated mice was significantly increased. In the group of animals treated with paraquat and vitamin C showed significant reduction in the percentage of chromosomal aberrations. Treatment of mice with paraquat and vitamin C reduced the specific activity of AChE but the inhibitory effect for paraquat alone was more pronounced than paraquat and vitamin C. Vitamin C decreased this activity. It was also observed that paraquat alone increased cytochrome P450 activity and decreased the activity of GST while paraquat with vitamin C elevated GST activity, but reduced cytochrome P450 activities.
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Tue, 26 May 2015 04:24:34 GMT -08:00 http://www.scopemed.org/?mno=189768
Ultrastructure and Electrophysiological Studies on the Sense Organs of the Cotton Leaf Worm Spodoptera littoralis (Boisd.) http://www.scopemed.org/?mno=189766 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Ibrahim Gaaboub* and Ehab Tousson.
The present work was directed to study the possibility of using ultrastructure and electrophysiological techniques to distinguish all the sensory sensilla on the antennae and tarsi of female S. littoralis, as a trail to understand the insect chemical communication system. Relatively little is still known about the types, location and functions of S. littoralis sensory organs. The sensory organs on the antennae and on the tarsi of female S. littoralis were visualized by scanning and transmission electron microscopy. The surface of the tarsus is covered with scales overlapped together and is provided with sense sensilla that found on the ventral and lateral surface of the tarsus. Two basic types of sensilla were found on the tarsus of the prothoracic legs, the mechanosensory sensilla (squamiformia) that have one neuron, and the contact chemosensory sensilla (trichodeum, chaeticum and styloconica) that are multimodal receptors and have five neurons. While three basic types of sensilla were identified on the antennae, mechanosensory sensilla (squamiformia, chaeticum, auricillica and coeloconia), chemosensory sensilla as on the tarsus (styloconica, basiconica and small chemoreceptor pag) and olfactory sensilla (trichodeum) that have many neurons. The identification of the different types of sensilla on the tarsus and antenna will serve for electrophysiological studies, which can be made on them to clarify their functions.
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Tue, 26 May 2015 04:22:30 GMT -08:00 http://www.scopemed.org/?mno=189766
Effect of Silymarin on Ribavirin-induced Molecular and Histopathological Changes. http://www.scopemed.org/?mno=189765 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
S. F. El-Abd.
Ribavirin is the most famous anti- C virus drug all over the world. Silymarin is one of the hepatoprotective drugs belong to the group of free-radical scavengers. Treating albino rats with prescribed dose of ribavirin (10mg/kg daily), induced many ultrastructure changes in the liver. The magnitude of such changes was time-dependant. After two and four weeks of treatment with Ribavirin, most of the organelles (e.g mitochondria) were degenerated. Moreover, the blood cells of Ribavirin treated sample showed highly damaged DNA as detected by (Comet assay) method. Treatment with Silymarin (7mg/kg daily) improved the histological and molecular alterations and reduced the incidence of hepatic and blood illness. It is speculated that, Silymarin as antioxidant may overcome the cytotoxic effect of Ribavirin, or it may block and stopping the reaction between the free radicals and rats molecular organelles.
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Tue, 26 May 2015 04:20:24 GMT -08:00 http://www.scopemed.org/?mno=189765
HISTOLOGICAL AND ULTRASTRUCTURAL CHANGES INDUCED BY PYRIPROXYFEN IN THE ANTENNAL GLAND OF FRESHWATER CRAYFISH PROCAMBARUS CLARKII (CRUSTACEA: DECAPODA) http://www.scopemed.org/?mno=189764 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Mona, M.H. Heiba, F.N. Sharshar, Kh. and El-Harty, E.A..
The histolgical and ultrastructural alterations induced in the antennal gland of freshwater crayfish Procambarus clarkii exposed to 1/10 LC50 of pyriproxyfen for 15 and 30 days were examined. The antennal gland is normally consisted of coelomosac, labyrinth and bladder. Exposure to pyriproxyfen led to histopathological changes which were clearly visible in the epithelial cells of labyrinth. The lesions were characterized by a loss of microvilli, moderate nuclear hypertrophy, a dilation of nuclear envelop, apparent cell sloughing and intensive secretory activity. Mitochondria were irregularly shaped and less abundant. The amount of smooth endoplasmic reticulum had increased and often displayed a striking degree of organization into extensive elongate parallel aggregates of tubular elements. Alterations in the antennal gland coelomosac (podocytes) included pyknosis, haemocyte infilteration. Many vesicles were observed filled with electron-dense material located in the cytoplasm of coelomosac. Moreover, the presence of dark granules within podoyctes of antennal gland was discussed.
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Tue, 26 May 2015 04:18:20 GMT -08:00 http://www.scopemed.org/?mno=189764
IMMUNOHISTOCHEMICAL IDENTIFICATION OF ARGININE VASOPRESSIN CONTAINING NEURONS AND FIBRES IN SOME HYPOTHALAMIC NUCLEI OF THE NEONATAL MOUSE http://www.scopemed.org/?mno=189763 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Ehab M. Tousson.
Arginine vasopressin (AVP) is a neuropeptide synthesized in neurons of the mammalian brain and released via the posterior pituitary into the bloodstream where it influences the maintenance of fluid homeostasis and blood pressure. Cellular identification and distribution of AVP in the mouse hypothalamic nuclei before vision functioning has never been reported before. The distribution of AVP producing cells and their projections were examined in the hypothalamus and in the hypothalamic nuclei of the neonatal CD1 mouse using immunohistochemistry (immunoperoxidase and immunofluorescent labelling methods). Clusters of neurons labelled for AVP immunoreactivity (AVP-ir) were found in the hypothalamic nuclei as in the paraventricular (PVN), supraoptic (SON) and suprachiasmatic nuclei (SCN) of the hypothalamus. Scattered AVP producing cells were also found in the lateral hypothalamus, fornix, stria terminalis and preoptic area. Heavily stained AVP-ir fibres were found in the paraventriculo-supraoptico-neurohypophyseal tract while scattered AVP-ir fibres were found in the lateral hypothalamus and in the stria terminalis. The bed nucleus of the stria terminalis (BNST) contains more AVP-ir cells in the neonatals than in adult mice.
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Tue, 26 May 2015 04:15:41 GMT -08:00 http://www.scopemed.org/?mno=189763
EFFECT OF DIFFERENT DIETARY LEVELS OF L-ASCORBIC ACID (VITAMIN C) ON GROWTH PARAMETERS AND SOME PHYSIOLOGICAL PROPERTIES OF SAROTHERODON GALILAEUS http://www.scopemed.org/?mno=189762 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Mohamed A. Sweilum.
Effect of different levels of L-ascorbic acid (0, 250, 500, 750, 1000, 1250 and 1500 mg/kg dry diet) on growth and physiological properties of Tilapia galilae (Sarotherodon galilaeus) were studied. Fish of an initial size of 12 cm for total length and 40 gm for body weight were stocked in concrete ponds (40 m2 area) at a rate of 5 fish / m2. At the end of experimental period, it was noticed that the final total length and body weight reached its highest values (27.5 cm and 186.5g) in fish fed diet containing 750 mg vitamin/kg diet. While, the specific growth rate and normalized biomass index give showed its maximum values (1.08 and 0.72) in case of fish fed diets containing 750 mg vitamin / kg diet. Similarly, the feed conversion ratio had its optimum value (2.85) and protein efficiency ratio reached its highest value (1.49) at the two pervious vitamin levels. The better biological indices of rearing fish (hepato, gonado and gastrosomatic indices) were recorded for fish fed with diets containing 750 mg vitamin / kg diet. The survival rate and total fish production had its maximum values (98% and 3.839 tons/feddan) for fish fed on the diet containing 750 mg vitamin / kg diet. It was also noticed that, the fish health was improved when fed on diets containing 750 and 1000 mg vitamin c, where the blood parameters and biochemical composition of muscles reached its highest values.
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Tue, 26 May 2015 04:13:42 GMT -08:00 http://www.scopemed.org/?mno=189762
IMPACT OF HEAVY METAL CONTAMINATION ON SEASONAL ABUNDANCE OF PLANKTONIC COPEPODS INHABITING MANGROVE AREA IN SAFAGA, RED SEA, EGYPT. http://www.scopemed.org/?mno=189760 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Ahmed H. ObuidAllah * AbdAllahT. AbdAllah ** Hussni M. Abu-Eldahab ***Nasser M. Abdul-Rahman * Ah-Doushy A. Mahdy.
The effect of heavy metal pollution on seasonal abundance of copepods inhabiting mangrove area at the Red Sea was studied. Planktonic copepods were sampled seasonally from two sites at the coastal area of the Red Sea. The first site was the mangrove area containing mangal trees at 17km South of Safaga. The second site was the marine biological station at Hurghada that was selected as a control site. Some ecological and physico-chemical parameters were measured at the two sampling sites including pH, salinity, dissolved oxygen, conductivity, air and water temperature, and turbidity. Also, the water concentration of zinc, cadmium, lead, copper, cobalt, nickel, strontium, lithium and chlorophyll-a was determined. Regression analysis and MANOVA statistical analysis were conducted to determine the effective ecological parameters on zooplankton distribution. Twenty-six species belonging to 17 genera of different copepod groups in addition to nauplius larvae and copepodite stages were identified from surface water of the two selected sites. Variable change in copepod density was pronounced in both sites. Significant regression relationship was found between copepod abundance and air temperature and dissolved oxygen (R=0.8, P
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Tue, 26 May 2015 04:11:12 GMT -08:00 http://www.scopemed.org/?mno=189760
COMPARATIVE ANATOMICAL STUDIES OF THE DORSAL LINGUAL SURFACE IN TWO AVIAN SPECIES WITH SPECIAL REFERENCE TO THE PATTERN OF KERATINIZATION http://www.scopemed.org/?mno=189758 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Abeer A. Alm-Eldeen.
Comparative morphological and histological features of tongues allow deducing a relationship between their structure and function, as reflected by an animal’s feeding habits. In the present study, the dorsal surface of pigeon’s (granivorous) and egret’s (insectivorous) tongues were studied using scanning electron and light microscopes. Scanning electron microscopic examination of the dorsal surface of pigeon’s tongue revealed many filiform papillae are distributed in definite areas, whereas other fungiform are irregularly scattered in between. However, examination of the egret’s tongue revealed that it is devoid of these two types of papillae. Giant papillae are observed in the posterior part of the lingual body in both pigeon and egret. Histological examination of the dorsal lingual epithelia of the both birds revealed that it consists of stratified squamous epithelium. In the pigeon, the outermost layer consists of shedding cells while in the egret, a thick keratinized layer is observed. A relationship between the histological structure of the lingual epithelium and the development of keratin expression was discussed. The present data revealed that the morphological and histological variations of both tongues may be related to their feeding habits.
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Tue, 26 May 2015 04:08:34 GMT -08:00 http://www.scopemed.org/?mno=189758
EFFECT OF SOME STRESS FACTORS ON CORTISOL HORMONE AND SUSCEPTIBILITY OF CULTURED OREOCHROMIS NILOTICUS FOR AEROMONAS SEPTICEMIA INFECTION http://www.scopemed.org/?mno=189756 2015-05-27T22-51-42Z
Source: THE EGYPTIAN JOURNAL OF EXPERIMENTAL BIOLOGY (Zoology)
Mohamed Wafeek Mohamed El-Sayd Abou El-Atta.
In April 2005 up to September 2005, twelve earthen ponds in special fish farm at El-Tal El-kaber Ismaelia governorate were chosen and divided into four groups in a triplicate manner. Ismaelia canal water irrigates the first and second groups; however, the third and fourth groups were irrigated with agriculture drainage water. Oreochromis niloticus were distributed at a rate of (3 fish/m3), except for the second treatment where the culture was semi-intensive (12 fish/m3).The differences in water resources and type of fish culture affect the quality of water with a significant increase in ammonia. As well as copper concentrations in ponds irrigated with agricultural drainage water. Moreover, fish exposed to the stress factors (stock density in Ismaelia canal and agricultural drainage water) showed some clinical and pathological signs including fins and tail rot with rough scales, severe oedema, eye opacity (uni, lateral or bilateral opacity), Pale gills, severe enlarged liver, hemorrhagic foci on liver surface, sever enlargement of spleen in addition to high rate of mortalities. Furthermore, high fish stock density (12 fish / m3) and the usage of agricultural drainage water in fish culture elevate plasma cortisol level, lowering gamma globulin and consequently increased rate of fish infection with bacterial diseases.
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Tue, 26 May 2015 04:06:05 GMT -08:00 http://www.scopemed.org/?mno=189756
In Memoriam on Assa Reichert (1943 - 2015) http://www.scopemed.org/?mno=189752 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Izet Masic.

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Tue, 26 May 2015 03:58:23 GMT -08:00 http://www.scopemed.org/?mno=189752
The Most Influential Scientists in the Development of Medical Informatics (6): Heinz Zemanek http://www.scopemed.org/?mno=189750 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Izet Masic.

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Tue, 26 May 2015 03:55:34 GMT -08:00 http://www.scopemed.org/?mno=189750
Dermatoglyphics and Reproductive Risk in a Family with Robertsonian Translocation 14q;21q http://www.scopemed.org/?mno=189748 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Selim Kolgeci, Jehona Kolgeci, Mehmedali Azemi, Aferdita Daka, Ruke Shala-Beqiraj, Ilir Kurtishi, Mentor Sopjani.
Aim: The present study is carried out to evaluate the risk of giving birth to children with Down syndrome in a family with Robertsonian translocation 14q;21q, and to find the dermatoglyphic changes present in carriers of this translocation. Methods: Cytogenetics diagnosis has been made according to Moorhead and Seabright method, while the analysis of prints (dermatoglyphics analysis) was made with the Cummins and Midlo method. Results: Cytogenetic diagnosis has been made in a couple who suffered the spontaneous miscarriages and children with Down syndrome. Robertsonian translocation between chromosomes 14 and 21 (45, XX, der (14; 21) (q10; q10)) was found in a female partner who had four pregnancies, in two of which was found fetus karyotype with trisomy in chromosome 21 and pregnancies were terminated. The outcome of fourth pregnancy was twin birth, one of them with normal karyotype and another with Down syndrome due to Robertsonian translocation inherited by mother side. Specific dermatoglyphics traits are found in the child carrying Down syndrome, whereas several traits of dermatoglyphics characteristic of Down syndrome have been displayed among the silent carriers of Robertsonian translocation 14q;21q. Conclusion: Robertsonian translocation found in female partner was the cause of spontaneous miscarriages, of giving birth to a child with Down syndrome, and of trisomy of chromosome 21 due to translocation in two pregnancies.
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Tue, 26 May 2015 03:53:51 GMT -08:00 http://www.scopemed.org/?mno=189748
Successful Implantation of Bipolar Epicardial Leads and Dual Chamber Pacemaker in Infant After Postoperative Atrioventricular Heart Block http://www.scopemed.org/?mno=189746 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Edin Omerbasic, Ilirijana Haxhibeqiri Karabdic, Elnur Tahirovic.
Total atrioventricular (AV) block is inconvenient and serious complication of open heart surgery. Permanent total AV block requires the implantation of permanent pacemaker in order to allow normal hemodynamics and patient's survival. In infancy additional challenge is the surgical approach, the selection of electrodes and PM, as well as place of implantation. We are publishing case report of successful double-chamber DDD pacemaker implantation at an infant born with Fallot tetralogy and with low birth weight due to complete AV block after primary surgical correction of these congenital defects.
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Tue, 26 May 2015 03:48:35 GMT -08:00 http://www.scopemed.org/?mno=189746
Information Retrieval in Telemedicine: a Comparative Study on Bibliographic Databases http://www.scopemed.org/?mno=189745 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Maryam Ahmadi, Roghayeh Ershad Sarabi, Roohangiz Jamshidi Orak, Kambiz Bahaadinbeigy.
Background and Aims: The first step in each systematic review is selection of the most valid database that can provide the highest number of relevant references. This study was carried out to determine the most suitable database for information retrieval in telemedicine field. Methods: Cinhal, PubMed, Web of Science and Scopus databases were searched for telemedicine matched with Education, cost benefit and patient satisfaction. After analysis of the obtained results, the accuracy coefficient, sensitivity, uniqueness and overlap of databases were calculated. Results: The studied databases differed in the number of retrieved articles. PubMed was identified as the most suitable database for retrieving information on the selected topics with the accuracy and sensitivity ratios of 50.7% and 61.4% respectively. The uniqueness percent of retrieved articles ranged from 38% for Pubmed to 3.0% for Cinhal. The highest overlap rate (18.6%) was found between PubMed and Web of Science. Less than 1% of articles have been indexed in all searched databases. Conclusion: PubMed is suggested as the most suitable database for starting search in telemedicine and after PubMed, Scopus and Web of Science can retrieve about 90% of the relevant articles.
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Tue, 26 May 2015 03:46:59 GMT -08:00 http://www.scopemed.org/?mno=189745
Education and Training for Major Incidents Through Medical Response to Major Incidents–MRMI course http://www.scopemed.org/?mno=189744 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Josip Samardzic, Boris Hreckovski, Ismar Hasukic.
Incidence of major incidents nowadays is in constant growth, especially in last decade. Main goal of all health systems is to minimize and prevent tragic outcomes of major incidents, thus reducing morbidity and mortality and psychological and physical suffering. Lessons learned from Major Incidents throughout the World point out that tragical outcomes could be avoided through adequate preparation and planning. Necessity to plan and to educate to response to Major incident is greater than ever. Finally it is legal obligation that every hospital has plan in case of Major Incident. Effective planning must incorporate: identification of risks, methods of prevention, identification of all recourses, anticipation of errors and detailed protocol of response for each participant. Knowledge and skills needed for Major incident situations must be adopted through interactive training and practical exercise („learning by doing„). That can be achieved by field exercises and by simulation model. Simulation model has many advantages and enables simultaneous education and training of all participants; scene, transport, hospitals, communication and command which than can be evaluated through objective outcomes. The goal is to train medical staff in real time, on position they are assigned to, with available resources in conditions of Major incident.
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Tue, 26 May 2015 03:45:42 GMT -08:00 http://www.scopemed.org/?mno=189744
Data Standards in Tele-radiology http://www.scopemed.org/?mno=189743 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Mansoor Fatehi, Reza Safdari, Marjan Ghazisaeidi, Mohamad Jebraeily, Mahdi Habibi-koolaee.
Data standards play an important role to provide interoperability among different system. As other applications of telemedicine, the tele-radiology needs these standards to work properly. In this article, we conducted a review to introduce some data standards about tele-radiology. By searching PUBMED and Google Scholar database, we find more relevant articles about data standards in tele-radiology. Three categories of standards identified, including data interchange, document and terminology standards. Data interchange standards, including those which facilitate the understanding of the format of a massage between systems, such as DICOM and HL7. Document standards, including those which facilitate the contents of a massage, such as DICOM SR and HL7 CDA. And terminology standards, including those which facilitate the understanding of concepts of the domain. Since, the harmonization between different standards are important to meet interoperability, so the more effort is needed to conduct harmonization between tele-radiology standards and other domain.
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Tue, 26 May 2015 03:44:13 GMT -08:00 http://www.scopemed.org/?mno=189743
Diabetes Research in Iran: a Scientometric Analysis of Publications Output http://www.scopemed.org/?mno=189742 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Masoud Rasolabadi, Shahnaz Khaledi, Marlin Ardalan, Marya Maryam Kalhor, Susan Penjvini, Alireza Gharib.
Introduction: In the developing countries, diabetes mellitus as a chronic diseases, have replaced infectious diseases as the main causes of morbidity and mortality. International Diabetes Federation (IDF) recently estimates 382 million people have diabetes globally and more than 34.6 million people in the Middle East Region and this number will increase to 67.9 million by 2035. The aim of this study was to analyze Iran’s research performance on diabetes in national and international context. Methods: This Scientometric analysis is based on the Iranian publication data in diabetes research retrieved from the Scopus citation database till the end of 2014. The string used to retrieve the data was developed using “diabetes” keyword in title, abstract and keywords, and finally Iran in the affiliation field was our main string. Results: Iran’s cumulative publication output in diabetes research consisted of 4425 papers from 1968 to 2014, with an average number of 96.2 papers per year and an annual average growth rate of 25.5%. Iran ranked 25th place with 4425 papers among top 25 countries with a global share of 0.72 %. Average of Iran’s publication output was 6.19 citations per paper. The average citation per paper for Iranian publications in diabetes research increased from 1.63 during 1968-1999 to 10.42 for 2014. Conclusions: Although diabetic population of Iran is increasing, number of diabetes research is not remarkable. International Diabetes Federation suggested increased funding for research in diabetes in Iran for cost-effective diabetes prevention and treatment. In addition to universal and comprehensive services for diabetes care and treatment provided by Iranian health care system, Iranian policy makers should invest more on diabetes research.
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Tue, 26 May 2015 03:42:49 GMT -08:00 http://www.scopemed.org/?mno=189742
Barriers to Research Activities from the Perspective of the Students of Isfahan University of Medical Sciences http://www.scopemed.org/?mno=189741 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Hasan Ashrafi-rizi, Zarmehr Fateme, Zahra Ghazavi Khorasgani, Zahra Kazempour, Sona Taebi Imani.
Introduction: Necessity to establish a coherent and targeted research context in order to development of any country is increasingly important. But the basic step in creating an effective research context would be enrichment motivation of researchers especially students and resolve barriers of research. Therefore, the purpose of this study was to determine barriers of research activities from the perspective of students of Isfahan University of Medical Sciences. Methods: This is research. Data was collected with author made questionnaire. The study sample consisted of students from Isfahan medical university and sample size based on Krejcie and Morgan table was 357. Sampling was Stratified Random. The validity of questionnaire confirmed by Library and information professionals and reliability based on Cronbach`s Alpha was 0.933, respectively. The type of descriptive statistics was (percentage, frequency and mean) and inferential statistics (T-test, ANOVA, one-Sample Statistics) and SPSS software was used. Findings: Results showed that the mean of barriers to research activities among students of Isfahan University of Medical Sciences was 3.89 ± 0. 483. The highest mean was related to density of students’ curriculum (4.22± 0.968) and lowest mean related to lack of access to appropriate library resources. Also, the mean of research activities `s barriers, according to aspects showed that the mean in individual barriers level (4.06±0.635) was more than other aspects: social and cultural aspects (4.01± 0.661), economical aspect (4.04± 0.787) and organizational barriers (3.78±0.503) . The lowest mean was related to organizational barriers. Also there is no difference between mean of research activities’ barriers of student of Isfahan University of Medical Sciences with regarded of gender, level of education and college. Conclusion: According to results of this research , although, the main barriers between students was individual barriers such as: lack of sufficient familiarity with research methods, insufficient experience in research and lack of familiarity with the terms of the articles in publication , but other aspects like economic, cultural , social and organizational was in bad condition too. Therefore it is suggested that workshops related to research methodologies is executed, like proposal writing, writing articles in university especially for students and administrators support student`s research activities , effectively.
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Tue, 26 May 2015 03:41:22 GMT -08:00 http://www.scopemed.org/?mno=189741
Real Time Recognition of Heart Attack in a Smart Phone http://www.scopemed.org/?mno=189740 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Mahshid Zomorodi Rad, Saeed Rahati Ghuchani, Kambiz Bahaadinbeigy, Mohammad Mahdi Khalilzadeh.
Background: In many countries, including our own, cardiovascular disease is the most common cause of mortality and morbidity. Myocardial infarction (heart attack) is of particular importance in heart disease as well as time and type of reaction to acute myocardial infarction and these can be a determining factor in patients’ outcome. Methods: In order to reduce physician attendance time and keep patients informed about their condition, the smart phone as a common communication device has been used to process data and determine patients’ ECG signals. For ECG signal analysis, we used time domain methods for extracting the ST-segment as the most important feature of the signal to detect myocardial infarction and the thresholding methods and linear classifiers by LabVIEW Mobile Module were used to determine signal risk. Results: The sensitivity and specificity as criteria to evaluate the algorithm were 98% and 93.3% respectively in real time. Conclusions: This algorithm, because of the low computational load and high speed, makes it possible to run in a smart phone. Using Bluetooth to send the data from a portable monitoring system to a smart phone facilitates the real time applications. By using this program on the patient’s mobile, timely detection of infarction so to inform patients is possible and mobile services such as SMS and calling for a physician’s consultation can be done.
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Tue, 26 May 2015 03:38:09 GMT -08:00 http://www.scopemed.org/?mno=189740
The Influence of Aortic Valve Replacement on Functional Moderate - To-Severe Mitral Regurgitation in Patients with Aortic Valve Stenosis http://www.scopemed.org/?mno=189739 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Sejla Sehovic, Adnana Talic, Mirsad Kacila, Elnur Tahirovic.
Goal: The aim of this study was to show whether the concomitant functional mitral regurgitation in patients undergoing aortic valve replacement improves after this surgical procedure and to identify preoperative echocardiographic parameters that may influence the lack of improvement in mitral regurgitation (MR) after aortic valve replacement (AVR).Material and methods: The study included 45 patients with severe aortic stenosis and concomitant moderate to severe (+2/+3)mitral regurgitation. Results: The results of our study indicated an improvement in the degree of mitral regurgitation in 24 patients. The most prominent parameters responsible for the lack of improvement of mitral regurgitation in our study were LVIDd, ERO, RVol, pulmonary artery systolic pressure and left atrial diameter. Identification of echocardiographic predictors may assist in selection of patients for whom more aggressive surgical treatment is advised. Conclusion: Concomitant moderate to severe functional MR indicates that MV should be repaired or replaced at the time of aortic valve surgery where at least two of indicated predicted preoperative echocardiographic parameters are present.
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Tue, 26 May 2015 03:36:41 GMT -08:00 http://www.scopemed.org/?mno=189739
Relationship Between Psychological Empowerment and Productivity of Medical Librarians http://www.scopemed.org/?mno=189738 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Maliheh Zare, Fateme Zarmehr, Hasan Ashrafi-rizi.
Introduction: Psychological empowerment is really important and has remarkable effect on different organizational variables such as job satisfaction, organizational commitment, productivity, etc. So the aim of this study was to investigate the relationship between psychological empowerment and productivity of Librarians in Isfahan Medical University. Methods: This was correlational research. Data were collected through two questionnaires. Psychological empowerment questionnaire and the manpower productivity questionnaire of Gold. Smith Hersey which their content validity was confirmed by experts and their reliability was obtained by using Cronbach’s Alpha coefficient, 0.89 and 0.9 respectively. Due to limited statistical population, did not used sampling and review was taken via census. So 76 number of librarians were evaluated. Information were reported on both descriptive and inferential statistics (correlation coefficient tests Pearson, Spearman, T-test, ANOVA), and analyzed by using the SPSS19 software. Findings: In our study, the trust between partners and efficacy with productivity had the highest correlation. Also there was a direct relationship between psychological empowerment and the productivity of labor (r =0.204). In other words, with rising of mean score of psychological empowerment, the mean score of efficiency increase too. Conclusions: The results showed that if development programs of librarian’s psychological empowerment increase in order to their productivity, librarians carry out their duties with better sense. Also with using the capabilities of librarians, the development of creativity with happen and organizational productivity will increase.
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Tue, 26 May 2015 03:35:17 GMT -08:00 http://www.scopemed.org/?mno=189738
Development of a Fuzzy Decision Support System to Determine the Severity of Obstructive Pulmonary in Chemical Injured Victims http://www.scopemed.org/?mno=189737 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Taha Samad-Soltani, Mostafa Ghanei, Mostafa Langarizadeh.
Background: Chronic Obstructive Pulmonary Disease (COPD) is the most common known complication of exposure to mustard gas. Thus, all clinical guidelines have provided some recommendation for diagnosis, clinical management and treatment of this disease. Decision support systems are used to increase the acceptance of clinical guidelines. The purpose of this research is to develop a CDSS to determine the severity of COPD in chemical injured victims. Objectives: Development of a decision support system to determine the severity of COPD. Patients and Methods: First, the variables influencing to determining the severity of the disease was classified through studying the clinical guidelines. Then, the fuzzy model was implemented. To testing the system, the data from 50 patients were used. Results: the overall accuracy in determining the severity of the injury is equal to 92%, these indicators reflect the proper functioning of the system to assist the physician regarding the diagnosis of chronic obstructive pulmonary disease and determining its severity. Conclusions: The CDSS has efficient results and satisfactory performance. Although, the medical expert systems cannot be expected to provide 100 percent correct responses, however, they can be useful in the areas of patient management, diagnosis and treatment planning.
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Tue, 26 May 2015 03:33:47 GMT -08:00 http://www.scopemed.org/?mno=189737
Evaluation of Biocompatibility of Root Canal Sealers on L929 Fibroblasts with Multiscan EX Spectrophotometer http://www.scopemed.org/?mno=189736 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Alma Konjhodzic-Prcic, Selma Jakupovic, Lajla Hasic- Brankovic, Amra Vukovic.
Introduction: The purpose of the current study was to estimate the biocompatibility of endodontic sealers with different bases on L929 mouse fibroblasts permanent cell line using Multiscan EX Spectrophotometer. Materials and Methods: Endodontics sealers used in this study were GuttaFlow (Roeko) silicone based sealer, AH plus (De Tray-DENTSPLY) epoxy resin based, Apexit (Vivadent) calcium hydroxide based and Endorez (Ultradent) methacrylate based sealer. Sealer were tested trough time, freshly mixed 24 h, 48h and 7 days after setting. Biocompatibility was determinate on permanent cell lines L929 mouse fibroblasts trough cytotoxicity using MTT assay. Level of absorption was measured with multi scan EX spectrophotometer on length 420-600 nm. Results: Sealer based on calcium hydroxide Apexit Plus, GuttaFlow silicone based sealer and AH plus epoxy resin based sealer, have shown a low cytotoxicity through the all periods of time on culture of L292 mouse fibroblasts. Methacrylate based sealer, Endorez showed moderate cytotoxicity when freshly mixed and after 7 days. After 24 hours the visibility of the cells was 74,0% and after 48 hours 65,1%. which is slightly cytotoxic. Conclusions: According to results of this study there is a statistically significant difference among the groups p
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Tue, 26 May 2015 03:32:33 GMT -08:00 http://www.scopemed.org/?mno=189736
Correlation of Parathormone and the Serum Values of Acidum Uricum with Calcium Nephrolithiasis Examined by Three Different Methods of Diagnostics http://www.scopemed.org/?mno=189735 2015-05-27T22-51-42Z
Source: Acta Informatica Medica
Snjezana Milicevic, Radojka Bijelic, Branislava Jakovljevic.
Introduction. Urolithiasis is a multifactorial disease. Changes in social and economic living conditions have generated changes in chemical composition of urolith too. Although calcium is a predominant crystalline constituent of kidney stones in 80% of cases, metabolic disorders are not the main reason for their formation. Hyperparathyroidism may be a cause of occurrence of calcium lithiasis, however, the biggest number of its occurrence is not a consequence of elevated values of parathormone. Acid uric has a pervasive presence in all body fluids. The serum level of acid uric is determined by its rate of synthesis, rate of excretion by kidney and gastrointestinal tract, and metabolism. Goal. The goal of our study is to determine a correlation of calcium lithiasis of the upper part of the urinary tract with the parathormone values and the concomitant values of acidum uricum. Material and methods. The study was prospective and included 120 patients with calcium lithiasis of the upper part of urinary tract, divided in three age categories, 20-40 years, 40-60 years and older than 60 years. The diagnosis of calcium lithiasis of the upper part of the urinary tract was made on the basis of urinary tract ultrasonography, and kidney-ureter-bladder radiography (KUB) /intravenous urography (IVU), urine culture and chemical analysis of stone with patients who had a spontaneous emission of stone or following some of the methods for active removal of stone; with some patients non-contrast (NCCT) was carried out too. All patients were subjected to the laboratory analysis of the serum level of acidum uricum and parathormone. Results. With observed 120 patients suffering from calcium urolithiasis, who belonged to adult population, no patient had an elevated value of parathormone, while three patients (2.5%) had the values of acidum uricum higher than the reference values. The average value (for both parameters) was the lowest with the youngest patients and vice versa, and only in the group of 40 to 60 years of age there were patients whose values of the acidum uricum parameter was outside the interval of reference values; the other age groups did not have such values. Based on the analysis of the variance, as a statistical method, it was determined that the average values of acidum uricum in different age groups were statistically significantly different, which is not the case for the parameter parathormone. (p>0,05). Conclusion. The biggest number of nephrolithiasis is not a consequence of elevated values of parathormone. Hyperuricosemia may be present with calcium urolithiasis, without participation in forming kidney stones, most probably as an indirect sign of the existence of the initial insulin resistance and metabolic disease.
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Tue, 26 May 2015 03:31:21 GMT -08:00 http://www.scopemed.org/?mno=189735
Clinical Assessment and Implication of Olfactory Dysfunction in Neuropsychiatric Disorders of Childhood and Adulthood: A Review of Literature http://www.scopemed.org/?mno=185073 2015-05-27T22-51-42Z
Source: The Journal of Neurobehavioral Sciences
Yasin Yılmaz, Ezgi İnce, Halim Uğurlu, Alper Baş, Burak Tatlı, İbrahim Balcıoğlu.
Olfactory function comes into prominence in the neuroscience study area after revealing that olfactory dysfunction is considered as an early diagnostic pre-motor biomarker of Parkinson’s disease. Researchers have also examined the sense of smell in detail in patients with other neuropsychiatric disorders. Here, we present data from a systematic literature review in olfactory function in child and adult neuropsychiatric disorders. We have researched autism spectrum disorders (ASD), epilepsy, attention-deficit/hyperactivity disorder (ADHD), schizophrenia, bipolar disorder, eating disorders, and obsessive-compulsive disorder (OCD). Due to smell test techniques and heterogeneity of studies, the total number of studies was limited. The disorders were grouped according to smell test techniques. The most commonly-used tests were Sniffin Sticks Test (SST) and the University of Pennsylvania Smell Identification Test (UPSIT). Although some researcher did not find any significant impairment in olfaction, most studies indicated that olfactory dysfunction was very striking, especially in disorders involving in the dopaminergic pathway (e.g., ADHD, autism, and schizophrenia). In this review, possible future diagnostic or prognostic markers of olfactory dysfunction in neuropsychiatric disorders have been discussed. More studies that combine imaging methods, the electrophysiologic system, and genetic research are needed to clarify the relationship between olfaction and neuropsychiatric disorders.
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Tue, 26 May 2015 03:09:56 GMT -08:00 http://www.scopemed.org/?mno=185073