ScopeMed - RSShttp://www.scopemed.orgScopeMed RSSen-us Copyright © 2011 ScopeMed All rights reserved. ScopeMedhttp://www.scopemed.org/img/logo-scopemed-ttk.gifhttp://www.scopemed.org 2015-03-06T20-21-51Z Discovery of predictive biomarker candidates for intrinsic resistance to FOLFOX chemotherapy in colon cancer using a Top Down LC-MALDI approach http://www.scopemed.org/?mno=177383 2015-03-06T20-21-51Z
Source: Journal of Molecular Pathophysiology
Florian Tobias Unger, Markus Meyer, Hartmut Juhl, Kerstin Anneliese David.
Chemo resistance of cancer cells to chemotherapeutics is a main obstacle in chemotherapy to a successful outcome especially in first line, but also in later stages of chemotherapy. Chemotherapeutic agents are still the backbone of colorectal cancer therapy, but molecular determinants of chemoresistance are still lacking. The proteome of each cell is responsible for fundamental biological processes and also makes up the bulk of pharmaceutical targets and potential biomarkers. In this study, we used a newly developed top down LC-MALDI-MS-MS workflow to analyze the low molecular weight proteome of chemosensitive and chemoresistant cell lines in order to discover protein biomarker for intrinsic chemoresistance to FOLFOX chemotherapy in colorectal cancer. The discovery of predictive biomarkers for chemoresistance and the identification of molecular mechanisms underlying intrinsic chemoresistance could tremendously promote individualized chemotherapy.
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Fri, 06 Mar 2015 12:11:51 GMT -08:00 http://www.scopemed.org/?mno=177383
Neoadjuvant chemotherapy: role in locoregionally advanced oral cancers http://www.scopemed.org/?mno=180586 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Manpreet Singh Nanda, Azeem Mohiyuddin.
Background: Oral cancers are the most predominant cancers in our region due to the habit of betel nut chewing. The treatment protocols available have not given satisfactory results. Neoadjuvant chemotherapy has been tried out successfully in other cancers like cancer of larynx. Objectives: Our study aimed to assess the response of neoadjuvant chemotherapy in locally advanced oral cancer. Materials and Methods: A total of 40 patients were taken up for the study; 20 patients each in both study and the control groups. In the study group, patients were subjected to three cycles of neoadjuvant chemotherapy (cisplatin and 5-fluorouracil) after doing relevant investigations, later evaluated for resectability, and later taken up for surgery or radiotherapy depending on the response. In the control arm, all the patients were directly taken up for surgery. Results: The results showed that among the 20 patients who underwent neoadjuvant chemotherapy no one had complete response, 55% had partial response, 35% had stable disease, and 2 had progressive disease and were advised palliative radiotherapy only. Two patients in study arm were lost for follow-up. The remaining 16 patients in study arm and all 20 patients in control arm were taken up for surgery. The specimens were assessed histopathologically for positive margins. Almost equal incidence of positive margins was found in both arms. The patients were followed up for 2 years after surgery. The results showed marginally better disease-free survival in stage III disease patients who underwent neoadjuvant chemotherapy followed by surgery compared to those who had direct surgery; however, no major difference in patient with stage IVA disease was seen. Conclusion: Neoadjuvant chemotherapy in locally advanced oral cancers delays the progression of disease and gives partial response macroscopically. There was no significant improvement in locoregional control, disease-free survival, and overall survival of the patients.
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Fri, 06 Mar 2015 04:43:05 GMT -08:00 http://www.scopemed.org/?mno=180586
Eating behavior control model in obese adolescents based on individual beliefs and ideal body image http://www.scopemed.org/?mno=172276 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Maspiyah Maspiyah, Tjipto Suwandi, Ferry Efendi.
Background: Obesity epidemic has become a public health issue in Indonesia, particularly among children and adolescents. Research on the eating behavior control model, especially on individual belief and ideal body image among Indonesian adolescents, is limited. Objective: To develop a model of eating behavior control in obese adolescents based on individual belief and ideal body image. Materials and Methods: Data collected from 120 obese Indonesian adolescents aged 14–18 years in five senior high schools were used. Questionnaires and interviews were used to assess individual characteristic, belief, ideal body image, and social support. Model on eating behavior control was assessed using partial least square. Result: Individual belief through perceived threat, the threat of weight gain and the potential threat of a disease, leads to improved eating behavior control in obese adolescents. Ideal body image, consisting of appearance, evaluation, orientation, satisfaction, anxiety, and perception, can enhance good eating behavior. Conclusion: Favorable eating behavior of obese adolescents is affected by individual beliefs and ideal body image. Health educators should consider this issue with young people to develop strategies and intervention more relevant and appropriate.
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Fri, 06 Mar 2015 04:42:33 GMT -08:00 http://www.scopemed.org/?mno=172276
Visual outcome in traumatic cataract in Kashmir http://www.scopemed.org/?mno=164860 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Ejaz Akbar Wani, Nowsheen Abdullah Attar, Mohammad Ahsan Dar, Manzoor Qadir Keng, Raashid Maqbool Wani.
Background: The most common manifestation of ocular trauma is traumatic cataract, which remains a significant cause of visual impairment and physical disability in spite of diagnostic and therapeutic advances. Objective: To assess visual outcome in case of traumatic cataract and various factors pre- and postoperatively affecting it. Material and Methods: The study included 50 patients having traumatic cataract undergoing primary intraocular lens implantation. Personal information and history of the patient were recorded and detailed preoperative assessment was carried out. The surgeries performed were phacoemulsification and conventional extracapsular cataract extraction (ECCE) with lens implantation depending on preoperative status. Results: A total of 50 patients aged 3–55 years with mean±SD 24.28±14.17 were studied. There were 38 (76%) males and 12 (24%) females; 26 (52%) had closed globe and 24 (48%) open globe injuries. Phacoemulsification was performed in 42 cases (84%) and conventional ECCE in the rest. Posterior chamber intraocular lens (PCIOL) was implanted in 49 cases (41 in bag and 8 in sulcus) and in 1 case anterior chamber intraocular lens was implanted. The most common age group to be affected was between 10 and 30 years (average 22.57 years). Wooden stick was the most common mode of injury (24%) followed by stone chip (20%). Type of cataract was found to be cortical (50%), posterior subcapsular (28%), and total (22%). Paracentral corneal opacity was the most common preoperative complication found in 30 cases (60%). Regarding postoperative visual acuity at 1 week, it was 6/6 in 8 (16%) cases, 6/18 to 6/36 in 24 (48%) cases, and ≤6/60 in 18 (36%) cases. There was absolute improvement in best-corrected visual acuity (BCVA) at 6 months, which was 6/6 to 6/12 in 33 (66%) cases, 6/18 to 6/36 in 16 (32%) cases, and ≤ 6/60 in 1 (2%) case only. On comparison p-value for both was found to be 0.000 (statistically significant). Closed globe injuries had better results than open globe type. Striate keratitis and posterior capsular opacification were the most common postoperative complications found in 20% cases each. Two patients (4%) developed amblyopia. Conclusion: As youth and children are more prone to injury, adequate adult supervision and educational measures are necessary to reduce prevalence of these accidents. Phacoemulsification is the better surgery because of early refraction stabilization. PCIOL implantation in capsular bag has good results. Children
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Fri, 06 Mar 2015 04:42:04 GMT -08:00 http://www.scopemed.org/?mno=164860
Prostate cancer in a retroviral positive patient: A case report and review of the literature. http://www.scopemed.org/?mno=181687 2015-03-06T20-21-51Z
Source: Case Study and Case Report
Olabode Peter Oluwole, Terkaa Atim.
Malignancy occurs with increased frequency in the HIV-positive population. The true incidence of prostate cancer in this population is unknown. In the few cases that have been presented in the literature, prostate cancer in HIV-positive men appears to behave much like it does in HIV-negative men. Prostate cancer is the most common malignancy in men and the second leading cause of cancer death. Its incidence increases with age and it is more prevalent in African-American men. Though in the past, the incidence was said to be low among Sub-Saharan African men, recent studies have shown that it is becoming a public health concern. HIV disproportionately impacts ethnic groups with increased risk of prostate cancer and has been associated with increases in the incidence of certain malignancies. Despite the high prevalence of both diseases, there is relatively little literature about prostate cancer in HIV-positive patients. There is no consensus on how to screen or treat this patient population. Here we present a case report of a 65-year old man with prostate cancer who was incidentally found to be retroviral positive.
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Thu, 05 Mar 2015 06:19:25 GMT -08:00 http://www.scopemed.org/?mno=181687
Evaluation of Epidemiology and Etiology of Dental Injuries Observed in Children [Çocuklarda Görülen Diş Yaralanmalarının Etiyoloji ve Epidemiyolojilerinin Değerlendirilmesi] http://www.scopemed.org/?mno=177918 2015-03-06T20-21-51Z
Source: Medicine Science | International Medical Journal
Esra Kizilci, Pinar Demir.
Traumatic dental injuries(TDI) is an important public health problem because of its frequency, occurrence at a young age and the high cost treatment follow-up procedures reason for continuing forward in the life of the patient's. In scientific literature, TDI frequency has increased in the last 30 years. Knowing the etiological and epidemiological factors of traumatic dental injuries would significantly support physicians in diagnosis and treatment planning. This observational retrospective study aimed to describe the epidemiological characteristics of traumatic dental injuries of children under the age of 15. The results obtained in this study will be useful for the development of the prevention and treatment of this type of injury of the pediatric population.
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Thu, 05 Mar 2015 06:01:06 GMT -08:00 http://www.scopemed.org/?mno=177918
Association of physical activity, nature of job, and exercise with the prevalence of essential hypertension in the Tharparkar desert http://www.scopemed.org/?mno=161550 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Loung V Umedani.
Background: The prevalence of essential hypertension (EHTN) is quite low in individuals who perform more body activities and exercise as opposed to those who spend a sedentary lifestyle. Regular physical activity reduces the risk of obesity, adverse lipid profile, hypertension, and type 2 diabetes mellitus. Many studies are carried out globally to assess the prevalence of EHTN related to grades of physical activity and lifestyle patterns but fewer studies are been conducted for the desert areas. The present study was conducted at the Tharparkar desert characterized by shortness of rainfall and dry weather, which might affect sodium and water balance in the body and eventually blood pressure. Objectives: To study the association of physical activity, nature of job, and exercise with prevalence of EHTN in the people living in the Tharparkar desert. Materials and Methods: A randomized, descriptive population-based study was carried out in the Tharparkar desert, Pakistan. After getting approval from ethics review committee of the Aga Khan University, a total of 563 participants were selected randomly (295 males, 268 females) in 2012 from the Tharparkar desert, Pakistan. We recorded demographic and anthropometric data, levels of blood pressure, levels of daytime and on job physical activities, and exercise. Statistical analysis of the prevalence of EHTN and its association with various grades of physical activity in relation to the sedentary and active occupation and with exercise was carried out. Data were analyzed descriptively and categorically by using SPSS-21 for comparing the prevalence of EHTN with increased and decreased physical activities, exercise, and job with sedentary versus active lifestyle. The p-values of < 0.05 were considered statistically significant. Results: After getting approval from the ethics review committee, the mean age and prevalence of EHTN among the studied 563 participants from Tharparkar desert were assessed and found to be 37 (±16.4 years, range 10–82 years) and 81 (14.4%), respectively. Participants leading a sedentary lifestyle showed higher prevalence of EHTN (19.2%) than those leading an active lifestyle (1.9%). Participants having job with mild physical activity had higher prevalence of EHTN (19.4%) than those having jobs with active lifestyle (2.9%); p-values were
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=161550
Death rates of snakebites in Vadodara, mid-Gujarat: a 3-year study http://www.scopemed.org/?mno=740 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Akhilesh K Pathak.
Background: Snakebite is one of the important causes of death in India. The actual incidences of snakebites are more than the number declared from official hospital records because of underreporting of cases because of many reasons. It is the only poisoning in which typical seasonal variations are present, as the incidences are typically higher in monsoon season. Objectives: To determine the magnitude, seasonal trends, and death toll of snakebite cases. Materials and Methods: This retrospective study was conducted in the Department of Forensic Medicine, Sir Sayajirao General Hospital and Medical College, Vadodara, Gujarat, India, which is a tertiary-health-care center of mid-Gujarat. A total of 629 cases of snakebite poisoning were studied, which were reported during the span of 3 years (2006–2008), and the data were analyzed. Results: In the 3-year duration, all the data related to the distribution of cases, according to months and seasons, were studied with pattern of death, and we found that the incidences of snakebite were increasing every year with an average mortality of 5.7% and incidences are typically higher in monsoon seasons, which is from June to September in the mid-Gujarat region. We also analyzed the fatal events of snakebite cases in relation to the other medicolegal autopsies and revealed that the death caused by snakebites were contributing only 0.56% of the total load of medicolegal autopsies during the 3-year span of this study. Conclusion: Till date, no study has been carried out on snakebites in Vadodara, and our study shows that though it is a life-threatening emergency, ready availability and appropriate use of antivenom, quick mobilization of patients, and close monitoring in the hospital can help us to reduce the morbidity and mortality.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=740
Autoamputation of rectum as a result of neoadjuvant radiotherapy: a case report http://www.scopemed.org/?mno=164583 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Selim Yigit Yildiz, Murat Burc Yazicioglu, Ali Ciftci, Mehmet Ozyildiz, Hamdi Taner Turgut, Cagri Tiryaki.
Total mesorectal excision and neoadjuvant radiotherapy have been known to reduce the local recurrence in advanced rectal carcinoma. Radiotherapy still exerts harmful side effects in spite of several advancements over the years. Bowels are most commonly affected organs. In some rare cases, rectum, colon and small bowel perforation, and septic complications have been reported in the course of, or after, neoadjuvant radiotherapy. We report here a case of rectal autoamputation due to the side effect of neoadjuvant radiotherapy.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=164583
Comparison of fine-needle aspiration technique with Ziehl–Neelsen stains in diagnosis of tuberculous lymphadenitis http://www.scopemed.org/?mno=169065 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Jignasha M Patel, Kamini R Patel, Kamlesh Shah, Niraj U Patel, Hinal Baria, Prashant D Patel.
Background: Lymphadenopathy is one of the most common clinical presentation among patients. In developing countries such as India, tuberculous (TB) lymphadenitis is one of the common causes of lymphadenopathy. Cytomorphology with acid-fast staining is a valuable diagnostic tool in cases of tuberculosis. Objective: To describe pattern of TB lymphadenitis presentation, and to compare results of fine needle aspiration cytology (FNAC) and Ziehl–Neelsen (ZN) stain in the diagnosis of TB lymphadenitis. Materials and Methods: Total 351 patients of lymphadenopathy referred to the Department of Pathology, GMERS Medical College & Hospital, Vadodara, Gujarat, India, between March 2011 and December 2013included. FNAC was performed in all these patients and smears were prepared. Smears were stained with hematoxylin and eosin stain. ZN staining for acid-fast bacilli (AFB) was carried out on separate slide. Results: Maximum number of patients (162; 46.15%) were from age group of 11–30 years. Total 351 cases [179 (50.99%) females and 172 (49.00%) males] were included in the study. Of 351 cases, 173 (49.28%) had tuberculosis, 141 (40.17%) had lymphadenitis other than tuberculosis, and 37 (10.54%) had malignant lymphadenopathy, including 2 (0.56%) cases of primary malignancy (i.e., lymphoma) and 35 (09.97%) of metastasis to lymph nodes. Overall, 119 (33.90%) cases were found to be positive for AFB on ZN staining. Conclusion: FNAC is an optimally selected, efficient, easy to perform, and economical test for initial diagnostic workup in patients with TB lymphadenitis. Supplementation of ZN stain with FNAC increases the rates of diagnosis.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=169065
Study of neurological complications in relation to diabetes mellitus control and duration http://www.scopemed.org/?mno=170468 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Jaydev Mod, Karthik Natarajan, Ronak Modi, Mansur Ali, Hiren Parmar.
Background: Diabetes mellitus (DM) is a leading cause of morbidity and mortality in all age groups in both developed and developing countries. It is associated with significant morbidity and reduces life complications. Among all complications, neurological complications are the chief destroyer and affect patients in the years of their greatest economical and social productivity. Objectives: To evaluate all neurological complications of DM, to correlate the duration of DM with this neurological complication, and prevalence of the complications on the basis of control of DM. Material and Methods: This study was conducted in a tertiary-care hospital. Fifty patients with DM were studied. Their detailed history, physical examination, and laboratory investigations were noted. Result: In this study, total 50 patients [31 males (62%) and 19 females (38%)] were studied. In this study, 64% patients with neurological complication had DM for more than 10 years. Patients with DM having HbA1c value of >7.1 indicate poor control of DM. Conclusion: Chronic neurological complications are observed more commonly in patients with type 2 DM as compared to those with type 1 DM. Neurological complications are more common with uncontrolled DM, which reflects poor glycemic control that in turn has an impact on neurological complications of DM.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=170468
Khat use and Its Determinants among University students in Northwest Ethiopia: A multivariable analysis http://www.scopemed.org/?mno=169675 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Berihun Assefa Dachew, Berhanu Boru Bifftu, Bewket Tadesse Tiruneh.
Background: Khat (Catha edulis) chewing is becoming a significant public health problem, and it becomes a common practice among high school, college, and university students. Objective: This study was conducted to assess the prevalence and determinants of khat chewing among Gondar University students in Northwest Ethiopia. Materials and Methods: The study was conducted among 872 randomly selected students in April 2014. A structured self-administered questionnaire was used to collect the data. Descriptive statistics and logistic regression were performed to examine the prevalence and predictors of current use of khat. Results: The lifetime and current prevalence of khat chewing among respondents was 17.9% (95% CI: 15.3–20.5) and 13.6% (95% CI: 11.4–15.9), respectively. Mental distress (adjusted odds ratio (AOR): 1.66 (95% CI: 1.05–2.61)), having friends who chewed khat (AOR: 3.9 (95% CI: 1.65–5.21)), cigarette smoking (AOR: 18 (95% CI: 9.5–18)), increased classwork load (AOR: 1.9 (95% CI: 1.12–3.2)), and religious practice (AOR: 0.4 (95% CI: 0.24–0.71)) were found to be independent predictors of chewing. Conclusion: The current prevalence of khat chewing was found to be high. Actions targeting those determinants are essential to effectively reduce khat use among university students.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=169675
Treatment-seeking behavior of elderly in Haryana: an evaluation study http://www.scopemed.org/?mno=171420 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Jaideep Kumar, Amarjeet Singh Minhas, Abhik Ghosh.
Background: The proportion of the elderly population is gradually increasing in India. Hence, the need for the geriatric health-care services is on demand. For such services, the treatment-seeking behavior with associated reasons needs to be assessed. Objectives: To ascertain the treatment-seeking behavior of the elderly people in Haryana. Materials and Methods: A community-based, cross-sectional study was conducted on the elderly of Haryana with the help of semi-structured interview schedule. Total sample size of 400 consenting elderly people from the eight selected areas (four rural and four urban) of Haryana was considered for this objective. Results: The study showed that availability and effectiveness are the main reasons behind the choice of therapy and resource. Allopathy was the preferred therapy, and owing to availability factor, quack was approached as the first choice, whereas later replaced by allopathic doctor (MBBS) in the third stage of health-care resource choice. Conclusion: Allopathy remains as the top choice of therapy, followed by ayurveda. Immediate availability of quacks is the major factor for their choice as first health-care resources.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=171420
Prevalence and determinants of alcohol consumption among adult men in a coastal area of south India http://www.scopemed.org/?mno=171488 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Muthurajesh Easwaran, Joy Bazroy, Venkatachalam Jayaseelan, Zile Singh.
Background: Globally, harmful use of alcohol results in approximately 2.5 million deaths each year. Almost 4% of all deaths worldwide are attributed to alcohol. Prevalence of alcohol consumption is on a continuous rise in India. Objectives: To measure the prevalence and determinants of alcohol consumption among adult men in a coastal area of Pondicherry. Material and Methods: A community-based cross-sectional study was carried out at Kalapet, a coastal area in Pondicherry that comes under the field practice area of Department of Community Medicine, Pondicherry Institute of Medical Sciences. Study population consisted of 500 men aged 18 and above. A systematic random sampling was used for sample selection. The study was conducted during January 2013 to December 2013. Data were collected by house-to-house survey using a predesigned questionnaire. Data were analyzed using SPSS, version 16.0. Simple proportions were calculated and 2-test was applied for statistical significance. A p-value
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=171488
Knowledge and practice of occupational infections and their prevention among medical interns of a tertiary-care teaching hospital in a south Indian city http://www.scopemed.org/?mno=29 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Arun MV Mohan, Ravish S Koratagere, Riyaz S Basha, Ranganath T Sobagaiah.
Background: Medical interns are a vulnerable group with regard to occupational infections (OI) such as HIV and hepatitis B/C, a large proportion of which are preventable by following universal precautions and to some extent by taking postexposure prophylaxis (PEP). Objective: To assess the knowledge and practices, regarding OIs, universal precautions, and PEP among medical interns. Materials and Methods: A cross-sectional study was performed in August 2011 on medical interns of a tertiary-care teaching hospital using a pretested, semi-structured, and self-administered questionnaire. All interns willing to participate (113 of 127 interns) were included. Results: More than 97.5% respondents were aware of the possibility of infection via mucocutaneous exposure and needlestick injury (NSI), but less than a third were aware of the recommended first aid for such exposures. Only 54% were aware of the recommended procedure of sharp waste disposal; 36.3% interns reported to have had occupational exposure (OE), majority being NSI and suturing being the main associated activity. Less than a fourth were aware of the ideal time to start PEP for HIV and the location of an emergency PEP dose. Around 65% were aware of the maximum time within which PEP should be started and the course duration of PEP. Only one intern reported to have taken PEP. Conclusion: One of every three interns had OE. Knowledge and practice of measures necessary to prevent OE and OI was poor. Students must be sensitized frequently during the course and before the start of internship using a powerful teaching–learning tool.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=29
KAP study on the assessment of needlestick injuries and occupational safety among health-care workers http://www.scopemed.org/?mno=114 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Asaithambi Anupriya, Subramanian Manivelan.
Background: Health-care workers (HCWs) are at substantial risk of acquiring blood-borne infections such as HIV, hepatitis B virus (HBV), hepatitis C virus (HCV) through needlestick injuries (NSIs). Objectives: To study the prevalence and associated factors of needlestick and sharp injuries (NSSIs) among the HCWs and to assess the level of awareness of the HCWs regarding NSSI. Materials and Methods: This cross-sectional study was conducted during the months of April–June 2014 in a tertiary-care hospital. The HCWs comprised of senior residents, interns, nurses, and laboratory technicians. A self-administered structured questionnaire consisting of questions regarding incidence of NSIs that occurred during last 3 months, circumstances of the injury and other relevant information were collected from the participants. Results: It was found that 64% participants experienced NSI at least once during the past 3 months. Of participants, 55% were vaccinated for hepatitis B whereas the rest were not vaccinated or did not complete the entire schedule. An NSI was experienced by 60.9% of participants during recapping of needle; 56.2% of HCW reported the incident to the infection control staff Conclusion: In addition to very high rates of NSIs, low safety practices including inadequate vaccination coverage, unavailability of infection control guidelines, and other preventive facilities were reported in this study. Formal training by health authorities in the local area about safe practices and availability of preventive facilities should be ensured regarding NSIs among HCWs.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=114
Evaluation of blood donor deferral causes: a tertiary-care center-based study http://www.scopemed.org/?mno=172790 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Dhaval N Chauhan, Killol N Desai, Harikrishna J Trivedi, Ashok S Agnihotri.
Background: Donor selection is necessary in addition to the screenings of blood bags for infectious diseases. Deferrals lead to loss of precious blood/components available for transfusion. For preventing this, we should be having knowledge of causes of deferral and their frequency. Objectives: To evaluate blood donor deferral causes and possibility of donor retrieval. Materials and Methods: Causes of donor deferral were evaluated retrospectively from January 2013 to July 2014 in the blood bank of C.U. Shah Medical College, Surendranagar, Gujarat, India. Totally 14,347 donors were screened, and of them, 660 donors were considered to be deferred. Results: Temporary deferral was more common than permanent deferral. The most common cause in permanent deferral was HBsAg positivity (23.64%). Causes among temporary deferral were anemia (Hb < 12.5%) (24.11%), followed by jaundice, weight < 45 kg, age older than 18 years, patients on antibiotic, previous donation in last 3 months, typhoid in last 1 year, dog bite, and so on. Conclusion: Analysis of deferral patterns may help medical personnel and doctors to be more focused in donor screening, especially of those who are having higher frequency. Temporarily deferred donors require proper follow-up and management so as not to lead to a diminished supply of future donors. It is important to determine the rate and causes of blood donor deferral for the safety of blood/component transfusion and to guide the recruitment efforts to prevent loss of precious blood/components at the local, national, and international levels.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=172790
Comparative study of lipid profile between episodic migraineurs and healthy volunteers http://www.scopemed.org/?mno=1130 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Venkatesan Rangan, Dinesh Thangavel, Mona Bedi, Ved Prakash Varshney, Mohan Jayabal, Venkidusamy Subramaniam.
Background: The lipid profile of migraineurs showed atherogenic condition. Cardiovascular and cerebrovascular events were found to be frequent and appeared one decade earlier in migraine patients compared with the general population. No comprehensive study is available regarding these aspects in migraineurs in India. Objectives: To compare lipid profile parameters between episodic migraineurs and healthy volunteers. Materials and Methods: This was a case–control study performed in a sample of migraine cases selected from the Outpatient Department, G.B. Pant Hospital, New Delhi, India, and normal healthy individuals as control group were chosen from the students of medicine, Maulana Azad Medical College, New Delhi, India. Migraineurs were selected based on the clinical diagnosis by neurologists, each fulfilling the International Headache Society criteria 2004. Subjects aged between 20 and 40 years were enrolled for study irrespective of the aura status. Lipid profile parameters studied were total cholesterol, high-density lipoprotein (HDL), very-low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and triglycerides. Results: The lipid profile of migraineurs showed abnormal condition. When LDL levels were compared, 24 of 54 cases and 5 of 30 controls showed abnormal levels (P = 0.020), whereas the remaining lipids showed no statistical significance between the two groups. Conclusion: Atherogenic lipid profile of migraineurs in our study coincided with the results of earlier studies. LDL levels were higher in cases when compared with those of controls. The values of total cholesterol, triglycerides, HDL, and VLDL levels did not differ significantly between the controls and the cases.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1130
A comparative evaluation of per rectal diclofenac sodium and paracetamol for postoperative analgesia in case of hydrocephalus http://www.scopemed.org/?mno=1050 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Mrugank M Bhavsar, Divya Kheskani, Parth Shah, Ashish Tyagi, Rama Upadhyaya.
Background: Hydrocephalus is one of the most painful conditions, especially in pediatric population. Analgesia after neurosurgery requires good communication and close cooperation between members of the perioperative team. Diclofenac is a nonsteroidal anti-inflammatory drug with pronounced antirheumatic, anti-inflammatory, analgesic, and antipyretic properties. Diclofenac inhibits prostaglandin synthesis, which contributes to inflammation, pain, and fever. Paracetamol produces analgesia and antipyresis by a mechanism similar to that of salicylate, which involves inhibition of prostaglandin synthesis. Objectives: To compare the analgesic efficacy of rectally administered diclofenac sodium and paracetamol postoperatively in patients with hydrocephalus for postoperative pain relief. Also, to compare side effects of both the drugs. Materials and Methods: Fifty patients aged 1-8 years scheduled for ventriculoperitoneal shunt under general anesthesia were selected for the study. All the patients were divided into two groups, Group D and Group P. At the end of surgery, 15 min before extubation, patients of Group D were rectally administered with inj. diclofenac 1 mg/kg whereas those of Group P with inj. paracetamol 15 mg/kg. Pain was assessed using Wong–Baker Faces Pain Rating Scale (WBFPS). When the score was 4 or more, then inj. paracetamol 15 mg/kg was administered intravenously as rescue analgesia. Patients were also observed for duration and analgesia. We have also compared hemodynamic parameters and complications in both the groups postoperatively. Results: Heart rate and SpO2 were stable in after the operation. Pain score on WBFPS was statistically nonsignificant between both the groups. Duration of analgesia was significantly longer in Group D than in Group P. Incidence of side effects and complications were also comparable in both the groups. Conclusion: We conclude that both paracetamol and diclofenac are very well tolerated by rectal route with prolonged duration of analgesia with diclofenac for postoperative pain relief in pediatric patients with hydrocephalus.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1050
Prevalence and determinants of overweight and obesity among affluent adolescents in Vijayawada city, Andhra Pradesh, India http://www.scopemed.org/?mno=1800 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Anil P Kumar, Md. G D Faisal.
Background: Obesity is an emergent problem in India, which is adding to disease burden. To prevent adult obesity, knowledge of prevalence and determinants of childhood obesity is essential. There is no study related to childhood obesity in the newly formed state of Andhra Pradesh; this would be the first one to document the prevalence and determinants in this region. Objective: To assess the prevalence and determinants of overweight and obesity in the affluent adolescents of Vijayawada city. Materials and Methods: A cross-sectional study with a sample size of 1721 students aged 12–15 years from randomly selected from seven affluent private schools with fee >20, 000 rupees per annum of Vijayawada from March 2013 to January 2014. The height and weight of the participants were measured and body mass index was calculated. A predesigned and pretested questionnaire was administered to assess the physical activity and dietary habits. Data were managed on an Excel spreadsheet and odds ratio was used to calculate strength of association. Variables showing P < 0.05 were considered as statistically significant risk and were subjected to multiple regression analysis. Results: The overall prevalence of overweight and obesity was 26.9% and 8.7%. Among the study participants, 50.6% were boys of which 15.7% were overweight and 5.4% were obese, and 49.38% were girls of which 11.2% were overweight and 3.4% were obese. The major risk factors include eating outside home, eating while watching TV, increased frequency of snacking outside, lack of outdoor sports, going to school on vehicles, prolonged school timings, long periods of watching TV/using computer, no daily exercise, both parents working, less hours of physical training at school, and absence of playground in the school. Conclusion: The overall prevalence of overweight and obesity was found to be 26.9% and 8.7%. The major risk factors were eating outside home, eating while watching TV, frequency of snacking outside, not playing outdoor games, both parents working, vehicular mode of transport to school, increased hours spent in school per day, not exercising daily, long periods of watching TV/using computer, less hours of physical training in school per week, and absence of playground in the school. Frequency of carbonated drinks, daytime sleep, and frequency of snacking at home were found not to influence the prevalence of overweight and obesity.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1800
Effectiveness of visual auditory kinesthetic tactile technique on reading level among children with dyslexia at Helikx Open School and Learning Centre, Salem http://www.scopemed.org/?mno=172315 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
J Manoranjini Jeyasekaran.
Background: Each and every child is special, born with a unique talent to explore this world. The word dyslexia is derived from the Greek language in which dys means “poor” or “inadequate” and lexis means “words” or “language”. Dyslexia describes about a different kind of mind, which is often gifted and productive, that learns the concept differently. Objectives: The main aim of the study was to bring the positive outcome of the reading level by examining the effectiveness of visual, auditory, kinesthetic, and tactile (VAKT) technique on reading level among children with dyslexia studying at Helikx Open School and Learning Centre. Materials and Methods: A Quasi-experimental one-group pretest–posttest design was adopted for this study. The reading level was assessed by using the Schonell Graded Word Reading Test. Thirty subjects were drawn by using purposive sampling technique and the intervention VAKT technique was used for children with dyslexia for 30 consecutive days followed by the post-reading level assessment, which revealed the improvement in the mean score value by 12%. Results: Multisensory (VAKT) teaching uses all learning pathways in the brain (visual, auditory, kinesthetic, and tactile) to enhance memory and learning and the ability of uplifting emotional, physical, and societal dimensions. Conclusion: VAKT is an effective method to improve the reading skill of the children with dyslexia, which ensures the enormous significance of learning, thereby influencing the wholesomeness of the child’s life.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=172315
Is iodine deficiency still a big threat? A descriptive cross-sectional study on iodine deficiency disorders among children aged 6–12 years in Shimoga district, Karnataka, India http://www.scopemed.org/?mno=1617 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Praveen Kumar N, MV Sagar, R Revathy, Manu Krishna.
Background: Iodine is an essential trace element for adults and children alike. Iodine deficiency manifests as goiter and cretinism, which causes developmental delays and other health problems. Objectives: To ascertain the prevalence of goiter in children aged 6–12 years and to determine iodine content in the salt they consume. Materials and Methods: All the taluks in Shimoga district were covered in the study. Population proportionate to size (PPS) sampling was done among children aged 6–12 years. Thirty villages (clusters) were selected using the PPS sampling method. In each identified cluster, all primary schools were enlisted, from where one was selected following the simple random sampling technique using a random number table for detailed survey. Total number of children surveyed was 2,700. A predesigned pretested pro forma was used to record data. Goiter was detected and graded by standard palpation method. Totally, 546 salt samples were collected for estimation of iodine content and 270 urine samples for urinary iodine excretion. The result was expressed in micrograms of iodine per deciliter urine (µg/dL). Salt and urine samples were sent to the IDD Monitoring Laboratory, Public Health Institute, Bangalore, Karnataka, India. Results: Total cases of goiter in Shimoga district were 251, which accounts for a total prevalence rate of 9.3%. Prevalence of goiter was found to be highest in the age group of 8–9 years (10.84%). The study showed a high goiter prevalence rate among girls aged 12 years (11.59%); 60.8% (332) salt samples had iodine levels of less than 15 ppm; 214 salt samples had iodine levels more than 15 ppm; 74.7% of all the urine samples showed iodine deficiency; and 183 showed severe iodine deficiency, whereas 11 showed moderate and 1 showed mild iodine deficiency. All the 27 urine samples collected from Sagar taluk showed severe iodine deficiency. Conclusion: Shimoga was found to be endemic for iodine deficiency disorders. Awareness generation activities have to be intensified so as to make people understand the importance of consuming iodized salt and about iodine deficiency disorders, if failed.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1617
Prevalence and determinants of overweight and obesity among elderly population in an urban area of Puducherry http://www.scopemed.org/?mno=1394 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
R Rajkamal, Zile Singh, P Stalin, E Muthurajesh.
Background: Obesity has reached epidemic proportions in India, with morbid obesity affecting 5% of the country’s population. Objectives: To measure the prevalence and determinants of overweight and obesity among elderly people in our urban field practice area of Puducherry, India. Material and Methods: A community-based cross-sectional study was carried out in Muthialpet, an urban area in Puducherry, which comes under the field practice area of Department of Community Medicine, Pondicherry Institute of Medical Sciences, Puducherry, India, from January to December 2013. Study population included 682 elderly aged 60 years and above. Data were collected by house-to-house survey using WHO STEPS questionnaire and analyzed using SPSS software, version 16.0. Simple proportions were calculated, and χ2-test was applied for statistical significance; p-value < 0.05 was considered as statistically significant. Results: Prevalence of overweight was 41.4% and of obesity was 4.5%. Religion, education, occupation, smoking, and alcohol consumption were found to be significantly associated with overweight/obesity. Conclusion: Prevalence of overweight was found to be high among elderly persons in the study area.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1394
Composite index of anthropometric failure and its important correlates: a study among under-5 children in a slum of Kolkata, West Bengal, India http://www.scopemed.org/?mno=1519 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Aparajita Dasgupta, Sanjaya Kumar Sahoo, Pranita Taraphadar, P S Preeti, Dhiraj Biswas, Amitava Kumar, Ishita Sarkar.
Background: In India, undernutrition remains a major public health problem despite several national programs targeting vulnerable groups, especially children. Objectives: To assess the nutritional status and morbidity profile of under-5 children and to elicit the explanatory and contextual factors of this malady. Materials and Methods: An observational, cross-sectional, descriptive study was conducted among under-5 children in a slum area of Kolkata, West Bengal, India. Anthropometric measurements were made following standard operative procedures and recall period of morbidity profile of last 2 weeks was recorded. Results: Of total 100 under-5 children assessed, the mean (standard deviation) of the sample was 23.52 (15.65) months. About 55% children were found to have anthropometric failure using composite index of anthropometric failure. However, with standard anthropometric indices such as weight for age, weight for height, height for age, and mid upper arm circumference prevalence of malnutrition were 42% (underweight), 30% (wasting), 28% (stunting), and 48% (undernutrition), respectively. About 48% children had some kind of morbidity of which acute respiratory infection accounted for 9%, diarrhea 11%, fever 9%, and skin infection 6%. Age [OR = 5.17 (2.09–12.76)], family type [OR = 4.11 (1.77–9.49)], literacy of mother [OR = 15.79 (5.98–42.35)], birth weight [OR = 4.2 (1.74–10.13)], birth order [OR = 5.25 (1.41–19.51)], and morbidity profile [OR = 6.35 (2.62–15.36)] are significantly associated with nutritional status. Conclusion: Accelerating the reduction in under-5 mortality is possible by expanding effective preventive and curative interventions that target the main causes of undernutrition. All efforts must be made to improve the nutritional status of the children. This will in the long run help in making this nation healthier, stronger, and more prosperous.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1519
Acute small bowel obstruction as a result of an appendicular knot encircling the terminal ileum: an exceptionally rare case report http://www.scopemed.org/?mno=1823 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Alok Ranjan, Kavita Kumari, Sukumar Jha.
In the developed world, small bowel obstruction accounts for 20% of all acute surgical admissions. The etiology for majority of these cases includes postoperative adhesions and hernia. However, appendicular knot is exceptionally rare. We report a case of a 65-year-old patient presented to the emergency room with complaint of abdominal pain, distension of abdomen, vomiting, and absolute constipation for 4 days. All the routine hematological and radiological investigations were carried out; the patient underwent laparotomy and was diagnosed with small bowel obstruction due to appendicular knot encircling the terminal ileum.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1823
Determinants of low birth weight in a rural area of Tamil Nadu, India: a case–control study http://www.scopemed.org/?mno=1686 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Kanimozhy Kandhasamy, Zile Singh.
Background: Birth weight of a child is an important indicator for reproductive health and general status of the population. Low birth weight (LBW) is considered as the single most predictor of infant mortality, especially of deaths within first month of life. Objectives: To find out the socio-demographic and maternal factors related to LBW. Materials and Methods: A case–control study was conducted in Kancheepuram district, Tamil Nadu, India, from January 2013 to September 2014. A total of 222 study participants, which included 111 cases and 111 controls, were interviewed using a structured questionnaire. Study variables included sociodemographic factors and maternal factors related to LBW. Modified BG Prasad Classification (April 2013) based on monthly per capita income was used to ascertain the socioeconomic status of the study participants. Data were entered in Microsoft Excel 2013 and were analyzed using SPSS software, version 16. Odds ratio (OR) was calculated. Multiple logistic regression analysis was done to adjust for confounders. Results: After adjusting for confounders, the significant risk factors associated with LBW were mother’s age less than 19 years [OR (95% CI) = 6.10 (1.47–25.23)], interpregnancy interval
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1686
Assessment of quality of life among anganwadi workers of Mandya city http://www.scopemed.org/?mno=1730 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
M P Sheethal, B R Harish, M Vinay.
Background: Quality of life refers to a subjective evaluation, which is embedded in a physical, psychological, social, and environmental context. Objectives: To determine the quality of life of anganwadi workers (AWWs) of Mandya city, Karnataka, India. Materials and Methods: A cross-sectional study was conducted from September to December 2011. All the AWWs from Mandya city were included. The World Health Organization Quality of Life—short version (WHOQoL-BREF) in Kannada, the local language, was administered to assess their quality of life. Results: The mean age of AWWs was 40.9 ± 8.3 years. Majority of them had completed their high school, and most felt that their overall quality of life was good. The mean scores were 69, 63, 58, and 56 for social, physical, psychological, and environmental domains, respectively. Conclusion: Of the four domains of quality of life, the social and physical domains were slightly higher than the environment and psychological domains.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=1730
Cecal volvulus: a case report http://www.scopemed.org/?mno=172410 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Madhusudhanan Devanathan, Bharani K RajKumar, Sasivannan Anbarasu, Medhun Kumar.
Cecal volvulus is an infrequently encountered clinical condition and an uncommon cause of intestinal obstruction. Patients with this condition may present with highly variable clinical presentations ranging from intermittent, self-limiting abdominal pain to acute abdominal pain associated with intestinal strangulation and sepsis. We present here a case of 54-year-old woman presented to our medical department with left hemiparesis and later on developed intestinal obstruction. She went for series of radiological investigations and was diagnosed as cecal volvulus. She underwent right hemicolectomy and ileocolic anastomosis. Her recovery was uneventful. The lack of familiarity with this condition is a factor contributing to delays in diagnostic and treatment. The objective of this review was to promote clinicians’ awareness of this disease through patient–case illustration, discussion of disease pathogenesis, clinical features, and management strategies.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=172410
Primary dysmenorrhea and its effect on quality of life in young girls http://www.scopemed.org/?mno=172430 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Tulika Joshi, Mool Raj Kural, Deepa Pandit Agrawal, Naziya Nagori Noor, Anjali Patil.
Background: Dysmenorrhea is a common gynecological condition with painful cramps of uterine origin. Severe dysmenorrhea pain is associated with restriction of activity and absence from workplace. The impact of dysmenorrhea on quality of life has been enunciated rarely, especially in Indian context. Objectives: To study the effect of primary dysmenorrhea on physical and social health status, work-related absenteeism, and work productivity in the young college-going girls. Material and Methods: In a cross-sectional study, data were collected among 310 young girls (18–25 years) on age at menarche, presence and absence of dysmenorrhea, premenstrual symptoms (PMS), quality of life, physical activity, and dietary habits using semi-structured questionnaire. Results: Dysmenorrhea was reported in 84.2% (261) of girls, and 15.8% (49) reported no dysmenorrhea. Majority of girls (91%) have reported PMS; symptoms were irritability (42.9%), leg cramps (40.4%), abdominal pain (40.1%), emotional instability (29.8%), fatigue (23.4%), dizziness (17.7%), breast pain (16.3%), and anxiety (10.3%). Girls who had dysmenorrhea were 4.9 times more likely to be absent in college, 3.1 times more chance of reduced physical activity, 3.2 times more chance of loss of concentration during workplace, and 2.4 times more likely to have poor work satisfaction compared with other girls with no dysmenorrhea (p < 0.05). Meal skipping was significantly associated with dysmenorrhea, and thus increases the prevalence of dysmenorrhea by 2.0 times (p < 0.05). Conclusion: Dysmenorrhea is a leading cause of absenteeism in colleges and has adverse effects on the quality of life of young girls.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=172430
Herpes simplex virus 2 infection in HIV-seropositive individuals in Tamil Nadu, India http://www.scopemed.org/?mno=172880 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Saramma M Jacob, Thatchinamoorthy Gopal, Sivasangeetha Kanagasabai, Anitha Durairaj, Kamala M Sushi, Ganesan Arumugam.
Background: Viral infection with Herpes Simplex Virus (HSV) is one of the most common opportunistic infections in seropositive patients of Human Immunodeficiency Virus (HIV). Studies have confirmed that genital herpes caused by HSV-2 has been associated with two- to threefold increased risk of HIV acquisition. Objective: To determine the seroprevalence of HSV-2 in HIV-positive patients. Materials and Methods: A prospective, cross-sectional study was conducted from July 2012 to January 2013 and HIV-positive patients were enrolled into the study after obtaining written informed consent. Demographic characteristics were recorded and serology test was performed using HSV-2 IgG ELISA test kit (Calbiotech, USA). Results were analyzed using X2-test. Results: Among 273 HIV-positive patients, 67% were men, 33% were women, and 1 transgender with an average age of 38.8 years. Overall, 50% of HIV-positive patients had HSV-2 IgG antibodies. Seroprevalence of HSV-2 among HIV-positive men and women was 47% and 57%, respectively. The highest HSV-2 seropositivity was detected in the age group of 36–45 years. X2-Analysis showed a statistically significant association between HSV-2 and HIV infection (X2 = 55.900, p = 0.0076). The median CD4 counts estimated in 100 patients were 563.50 cells/mm3. No significant difference was observed in the CD4 counts of those with or without HSV-2. Conclusion: HSV-2 prevalence was higher in HIV-positive women than in men. The implementation of continuous interventions for sexually transmitted infections and HIV will bring down the prevalence and spread of both HSV-2 and HIV infection.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=172880
A study of sandstone miner: notes from the field http://www.scopemed.org/?mno=172824 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Absar Ahmad.

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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=172824
An epidemiological study to explore the reasons of late admission of critically ill children to the hospital http://www.scopemed.org/?mno=173342 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Utkarsh Sharma, Arti Sharma, Roopa Hanspal, Janmejai Prasad Sharma, Alok Kumar.
Background: Prognosis, in terms of mortality and morbidity of a disease, also depends on the time gap between the initiation of a critical event and admission to the hospital. Objectives: To explore the reasons behind late admission of critically ill children to the hospital and to advice the parents to seek medical aid for their ailing children in time. Materials and Methods: This prospective study was conducted to explore the various reasons behind the late admission of critically ill patients between age group of 1 month and 12 years with special reference to medical emergencies admitted in child intensive therapy unit of LLRM Medical College and its associated SVBP Hospital, Meerut, Uttar Pradesh, India. Results: Of total admitted children, more of rural children (82.7%) were brought to the hospital in critical stage as compared to urban children (17.3%). Parents belonging to rural joint families had significantly poor interpretation of nature of illness as compared to those of urban nuclear families. Only 25.0% parents had realistic views about causative factor for illness whereas 64.7% parents had nonmedical beliefs for illness. There was significant delay in admission of female children as compared to male children. Conclusion: Rural background, poor economic status of parents, illiteracy, and lack of knowledge and awareness combined with superstitions and traditional misbeliefs were important factors behind late admission of critically ill children.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=173342
A study of spinal canal physiology in relation to interpedicular distance of lumbar vertebrae in Bundelkhand region http://www.scopemed.org/?mno=174525 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Shilpa Pandey, Amrish Tiwari.
Background: Interpedicular distance (IPD) determines the functioning of spine. There is a significant difference in the size of the lumbar vertebral canal in different ethnic groups, emphasizing physiology and clinical problems present in that group. Objectives: To identify IPD of lumbar vertebrae in the Bundelkhand region. Materials and Methods: This study was conducted on 65 dry human lumbar vertebrae (20 atypical and 45 typical) obtained from 65 cadavers in the Bundelkhand region. IPD was measured with the help of a sliding vernier caliper. Results: It was found that in the Bundelkhand region, mean transverse diameter (IPD) for typical lumbar vertebrae was 22.075 mm (range 15.4–30.5 mm) and for atypical lumbar vertebrae it was 25.16 mm (range 20.8–29.5 mm). Conclusion: In the Bundelkhand region, IPD shows slightly less value than that reported by other studies, which may be a risk factor to clinical problems attributed to this region.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=174525
Premarital screening of college students for carrier detection in thalassemia and sickle cell disease: need of the hour http://www.scopemed.org/?mno=175097 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Sonali Datar, Sandhya Poflee, Anuradha Shrikande.
Background: Hemoglobinopathies are a group of inherited conditions characterized by quantitative and qualitative abnormalities in the synthesis of hemoglobin. In India, the most prevalent hemoglobinopathies are thalassemia and sickle cell anemia. To reduce the burden of highly prevalent monogenic disorders, it is essential that disease progression be halted at the carrier stage. This can be done by carrier detection and genetic counseling in young individuals. In Central India, where prevalence of thalassemia and sickle cell anemia is high, premarital screening is being implemented for the first time in medical students for identification of asymptomatic carriers of these hemoglobinopathies and possible prevention of future high-risk marriages by genetic counseling. Objectives: The objectives of this study were to (1) determine the prevalence of asymptomatic carriers of sickle cell disease and thalassemia in first-year MBBS students; and (2) know the frequency of hemoglobinopathy carriers in different ethnic groups of this study group. Materials and Methods: This study was conducted at a Regional Hemoglobinopathy Detection and Management Centre of a tertiary-care hospital in central India in newly admitted medical students and was approved by the institutional ethics committee. Venous blood samples were analyzed for blood counts and solubility test positivity. Electrophoresis for pattern analysis and high-performance liquid chromatography for confirmation of diagnosis were used on each student. Results were analyzed with the help of statistical analysis. Results: Overall prevalence of hemoglobinopathies was 10%. Beta-Thalassemia trait was the most prevalent hemoglobinopathy followed by sickle cell trait. Presence of hemoglobinopathies was seen in varied ethnic groups. Conclusion: Importance of screening in young asymptomatic individuals is highlighted.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=175097
Fragile health policy of India: discussion on maternal health http://www.scopemed.org/?mno=176331 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Ranjit Kumar Dehury.
Since 2005, India has been relying on National Rural Health Mission—a flagship program under the Ministry of Health and Family Welfare to reduce country’s high maternal mortality. The main strategy has been recruitment of female health volunteer in villages, Accredited Social Health Activist, and expansion of infrastructure, mainly buildings, transport, and digitization. However, in comparison to this huge investment, the outcome improvement is very less. The transformation of policy to program needs suitable political and technical interventions. The marginalized groups are neglected due to both their ignorance and state apathy. This article attempts to touch upon these issues to show that the strategies are not competent enough unless the human resource and infrastructure expansion complement each other.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=176331
Anatomical variation in position, direction, and number of nutrient foramina in clavicles http://www.scopemed.org/?mno=176412 2015-03-06T20-21-51Z
Source: International Journal of Medical Science and Public Health
Nita A Tanna, Vilpa A Tanna.
Background: The clavicle is a modified long bone. It is the most important bone for transmission of weight from upper limb to the axial skeleton and for muscle attachments and is significant source for bone grafting. Objective: To determine the position, direction, and number of nutrient foramina in human clavicles. Materials and Methods: The study comprised 50 clavicles of unknown sex, which were obtained from the Department of Anatomy, Smt. BK Shah Medical Institute & Research Centre, Piparia, Vadodara, Gujarat, India. The foramen index was calculated using the Hughes formula. Results: The nutrient foramen was observed in all 50 (100%) clavicles. Total 82 foramina were observed. In 18.3% clavicles, nutrient foramen was present at medial 1/3rd region, in 72% at the middle 1/3rd, and in 9.8% at the lateral 1/3rd. Single foramen was present in 21(42%) clavicles & double foramina in 26 (52%) clavicles. The nutrient foramen was found on inferior surface in 49.2% clavicles and on posterior surface in 50.8% clavicles. The average distance of the foramen from the sternal end was 69.8 mm (6.98 cm) and the mean foraminal index was 49.01. Conclusion: The knowledge of nutrient foramina in clavicles is important in surgical procedures such as bone grafting and in microsurgical vascularized bone transplantation.
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Thu, 05 Mar 2015 05:58:51 GMT -08:00 http://www.scopemed.org/?mno=176412
Efficiency of Implementation of the Bologna Process at Medical Faculty, University of Sarajevo http://www.scopemed.org/?mno=181676 2015-03-06T20-21-51Z
Source: Materia Socio Medica
Izet Masic, Edin Begic.
Introduction: At the moment at Medical Faculty, University of Sarajevo, simultaneously exist two systems of teaching process, the old (pre-Bologna) and Bologna process. Goal: To show efficiency and justification of use of Bologna process at Medical Faculty,University of Sarajevo, through the prism of actual beneficiaries of this process, students, assessment of quality of medical education, and comparison of results of the teaching process evaluation between students studying according to the Bologna process and the old system. Materials and Methods: The study included period from 2012 to 2014, and had prospective character. Students of final (sixth) year were included, the last three generations of pre-Bologna, and three generations of the Bologna process, which completed their studies successfully. The study included 365 students (177 under the old system and 188 under the Bologna process), who had answered prepared questionnaire. Results: The presence of large number of female students, in both systems is significant. There were significant differences in opinion of students regarding the quality of space for administration and labor administration, informatization of the teaching process, the opinion of the objectivity of teachers in the assessment of the examination, and on-line access to their content. (p
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Thu, 05 Mar 2015 03:33:14 GMT -08:00 http://www.scopemed.org/?mno=181676
Roots of Pharmacy Practice in Bosnia and Herzegovina from the Ottoman and Austro-Hungarian Period: Attars’ Mission for Pharmaceutical Care http://www.scopemed.org/?mno=181675 2015-03-06T20-21-51Z
Source: Materia Socio Medica
Lejla Zunic, Izet Masic.
Significant role in how they played, and Jews Sephardim who came to Bosnia from Spain and Portugal in the late 15th and early 16th centuries. It is those were the first owners of districts–Shop herbs or pharmacy. Along with them were developed and Muslim attars, who founded and attars marketplace in Sarajevo. Experience and knowledge in the domain of medicine and healing practiced by old Bosnian Sephardim been acquired for centuries, is now mainly found on the shelves.
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Thu, 05 Mar 2015 03:31:25 GMT -08:00 http://www.scopemed.org/?mno=181675
The Non-carcinogenic Risk of Cadmium in Bottled Water in Different Age Groups Humans: Bandar Abbas City, Iran http://www.scopemed.org/?mno=181674 2015-03-06T20-21-51Z
Source: Materia Socio Medica
Yadolah Fakhri, Saeedeh Jafarzadeh, Bigard Moradi, Yahya Zandsalimi, Ghazaleh Langarizadeh, Leila Rasouli Amirhajeloo, Maryam Mirzaei.
Introduction: The presence of heavy metals such as cadmium in drinking water resources can be dangerous for human because of toxicity and biological accumulation. The consumption of water which contains Cd in high concentration can lead to Bone and Kidney diseases. Material and Methods: In this present study, the researcher collected 432 samples of bottled water in the popular marks in summer and winter from the surface of Bandar Abbas. The cadmium concentration was measured by atomic absorption Spectrophotometer in model DR2800 through the Dithizone method. CDI, R and HQ which are caused by Cd for adult men, women and children, have been calculated and evaluated through the equations of EPA and WHO. Results: Mean of 1.73±0.19 µg/l (M±SE) is lower than the standard of WHO and EPA. However, 33.2% of all the samples have concentrations more than the standard limit of WHO, and the concentrations of 22.4% of the samples are more than EPA’s standard. The CDI for different age groups is as following manner; Children>adult women>adult men. The CDI in children is more than twice as much as in the CDI for adult men and women. The mean of HQ order for different age groups is children>adult men>adult women. Since HQ of adult men (34E-5), adult women (31E-5) and children (84E-5), is lower than 1. Conclusion: It can be said that the population of Bandar Abbas is in a safe area regarding the HQ of the bottled water’s cadmium.
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Thu, 05 Mar 2015 03:28:47 GMT -08:00 http://www.scopemed.org/?mno=181674
The Diagnosis of Strangulation and Incarceration of Intestines: Clinically and Using Biomarkers http://www.scopemed.org/?mno=161197 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
Okan Murat Aktürk, Yeliz Aktürk, Erdinç Çetinkaya.
The primary cause of intestinal obstructions is postoperative adhesions. The other common causes are hernias, neoplasms, inflammatory bowel diseases and gallstones. The obstructions that are caused by adhesions resolve with medical therapy and does not require surgery. Strangulation of the intestines is the most frightening complication of obstruction. Which patients need urgent surgical intervention and who do not is an important issue because of the nature of the disease. Identifying clinical features of strangulation in intestinal obstruction may help detection of patients who require urgent intervention and get better outcomes.
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Thu, 05 Mar 2015 01:29:16 GMT -08:00 http://www.scopemed.org/?mno=161197
Comparative Assessment of Prebiotic Effects of Yeast Against Antibiotic Effects of Tetracycline and Red Acalypha on the Performance of Clarias Garipienus http://www.scopemed.org/?mno=176332 2015-03-06T20-21-51Z
Source: Journal of Animal Production Advances
Abayomi Akinfemi, Oluseun Motunrayo Osineye, Olufemi Olukayode Ashade.
The emergence of new infectious diseases and multi-drug resistant micro-organisms among man and his animals has become a public health concern globally. This study was conducted to compare the antimicrobial effects of Red acalypha, Tetracycline and yeast in the performance of Clarias gariepinus fingerlings. Three hundred and sixty (360) Clarias gariepinus fingerlings were allotted to each of these three (3) different additives and a control, (making up four (4) treatments) – (A) control, (B) red Acalypha, (C) tetracycline, and (D) yeast, using the same diet and each replicated thrice using completely randomized design in an eight (8) week feeding trials, to determine: Weight Gain, Specific Growth Rate, Feed conversion Ratio, Digestibility coefficient, Feed intake and White Blood Cell Count. The results revealed that treatment effect on Weight Gain (g) varied significantly (p< 0.05) with treatment D, that was fed the diet containing yeast recording the highest value of 924.2g as compared to treatments A (control), B (Red acalypha) and C (Tetracycline), recording 831.90, 812.8 and 917.6, respectively. The same trend was observed with specific growth rates. Treatment effect on white blood cell counts varied significantly (p
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Thu, 05 Mar 2015 00:34:19 GMT -08:00 http://www.scopemed.org/?mno=176332
A Cross-sectional Study on the Prevalence of Salmonella in Raw Milk in Tandojam and Surrounding Areas, Pakistan http://www.scopemed.org/?mno=178865 2015-03-06T20-21-51Z
Source: Journal of Animal Production Advances
Abdul Rasheed Baloch, Abdul Sattar Baloch, Allah Bux Baloch, Syed Shahid Faraz, Muhammad Asif Arain, Rab Nawaz Soomro, Sohail Ahmed Otho, Hafiz Muhammad Zakria, Imtiaz Hussain Raja Abbasi, Shahmir Ali Kalhoro, Muhammad Saeed, Abdul Majeed Baloch.
The study on the isolation of Salmonella in raw milk marketed in Tandojam town was carried out and raw milk samples were collected from village Saleh Makrani, Tandojam city and Moosa Khatiyan. Eleven milk samples from Saleh Makrani, thirty from Tandojam city and eleven from Moosa Khatiyan were collected which totaled 52 samples. Results indicated that of 2 milk samples collected from Village Saleh Makrani, 2 from Moosa Khatiyan and 4 from Tandojam city were found positive for Salmonella. Of the total 52 milk samples, Salmonella species was confirmed in eight samples. The overall prevalence of Salmonella was in the minimum-maximum range of 13.33-18.18 percent, showing average Salmonella prevalence of 15.38 percent. Hence the prevalence of Salmonella in milk was relatively higher in the samples collected from village of Haji Muhammad Saleh and Mossa Khatiyan.
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Thu, 05 Mar 2015 00:34:19 GMT -08:00 http://www.scopemed.org/?mno=178865
SİMÜLE HASTA KULLANIMINA İLİŞKİN ÖĞRENCİ GÖRÜŞLERİ http://www.scopemed.org/?mno=46284 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
Mevlüde Karadağ, Nurcan Çalışkan, Özge İşeri.
Purpose: The study was conducted in order to share in comparison the views of students regarding the use of simulated patients administering in the nursing program. Materials and methods: The study was conducted in the Department of Health Sciences School of Nursing which is located in the Middle Black Sea Region. The study population was formed with 70 students who have been ongoing Surgical Nursing Courses which are thought in the spring semester of second class of the 2011-2012 academic year. Thirty-five of these students were assigned to the study group randomly and 35 of them were assigned to the control group randomly. In the study, a case of patient with spinal cord trauma was used. The individual nursing care plans were prepared by study group via simulated patient study and control group via case study. Data of the study were collected with a questionnaire prepared by the researchers and the care plans prepared by the students. Chi-square and t tests were used to analyze the data. Results: The mean points of the students for the detection of the contribution of training methods on learning, planning of care and interventions were 89.7 out of 100 points in the study group and 80.57 out of 100 points in the control group and the difference was statistically significant (p
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Wed, 04 Mar 2015 23:56:45 GMT -08:00 http://www.scopemed.org/?mno=46284
ULTRASOUND GUIDED SUPRACLAVICULAR BLOCK FOR UPPER EXTREMITY PERIPHERAL ARTERY LACERATIONS; A FAST, EASY AND SAFE ANAESTHETIC MANAGEMENT http://www.scopemed.org/?mno=149830 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
Mustafa Özgür, Ali İhsan Hasde, Ayhan Köseoğlu.
SUMMARY Objective: Peripheral artery injures are important conditions which require an emergency response due to high mortality and morbidity. We, therefore, aimed our ultrasound guided supraclavicular block research on 14 patient cases, who each received emergency surgery for upper extremity peripheral artery lacerations; in conjunction with the literature. Methods: This study consisted of 14 patients, aged between 17-41 years old, who underwent surgery for upper extremity peripheral artery lacerations at the Antakya State Hospital Cardiovascular Surgery Clinic in 2013 (ASA I-II scores). Ultrasound guided supraclavicular brachial plexus blocks were administered to the patients in the supine position. The patients’ age, sex, height, weight, ASA scores, the localization of the trauma and additional trauma results, block formation time and block administration period were recorded. Results: The male/female ratio of the cases was 10/4, and radial artery lacerations (50%) were seen most frequently. There was no significant difference between the cases in terms of block formation time and block administration period. The mean block administration period was determined to be 8.45 min, and the mean block formation time was 10.7 min. Conclusion: The most severe complications for supraclavicular blocks are pneumothorax and vascular trauma. There were no complications in any of our cases in the intraoperative or early postoperative period. Consequently, we believe that ultrasound guided brachial plexus blocks can also be administered quickly and safely for peripheral artery lacerations.
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Wed, 04 Mar 2015 23:56:45 GMT -08:00 http://www.scopemed.org/?mno=149830
OBESITY IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA SURVIVORS: A LITERATURE REVIEW http://www.scopemed.org/?mno=151854 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
TUBA ARPACİ, EBRU KILIÇARSLAN TÖRÜNER.
Purpose: Obesity is one of the most important late effects that seen in survivors of childhood acute lymphoblastic leukemia. In this literature review, it is aimed to determine frequency of obesity in survivors of childhood acute lymphoblastic leukemia and characteristics of survivors. Materials and Methods: Review of the literature was made on Pubmed and Wiley Interscience and 13 studies were examined that conducted between 2003 and 2013. Results: Frequency of obesity in survivors is between 4.6% and 38.2%. The prevalence of obesity showed increases in female and survivors treated high dose cranial radiation therapy and survivors with long-term steroid exposure. Conclusion: It was shown that obesity is the most common late effects in survivors and there has been many late effects such as growth and development problems, cardiac anomalies, hypertension with obesity.
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Wed, 04 Mar 2015 23:56:45 GMT -08:00 http://www.scopemed.org/?mno=151854
Giant Lipoma Unusual Settle; Case Report http://www.scopemed.org/?mno=151587 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
Mehmet Sabri Balık, Adem Erkut, Yılmaz Güvercin, Recep Bedir, Başar Erdivanlı.
Herein we present a lipoma case which has an unusual settlement under deltoid muscle. The existence of lipomas in this area are very rare, so a biopsy should be done to make a differential diagnosis from other soft tissue mass. Serious complications can occur because of the close relationship between axiller nerve and the mass. Thus, separation of deltoid muscle from acromial origio provides a safe and wide approach and avoids complications. Additionally, it is a safe approach to make enough tonus of deltoid muscle fibers which are elongated and lost their tonus because of the mass effect.
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Wed, 04 Mar 2015 23:56:45 GMT -08:00 http://www.scopemed.org/?mno=151587
TOGETHER WİTH ATRİAL SEPTAL DEFECT, BİCUSPİD AORTA, PECTUS EXCAVATUM AND MENTAL RETARDATİON : A CASE REPORT http://www.scopemed.org/?mno=154823 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
Mustafa Necati Dağlı, Orhan Doğdu, Tolga Çakmak, Güney Sarıoğlu, Mehmet Ali Kobat.
In this case, patient with mental retardation accepted in our clinic complain with shortness of breath. Then physical examination inspection evident in the pectus excavatum and made Echocardiography Atrial septal defect (ASD) and bicuspid aortic consistent with the view were identified.Congenital abnormalities in patients with the aim of further evaluation of transesophageal echocardiography (TEE) planned. In TEE, 26 mm secundum atrial septal defect, bicuspid aortic valve was detected. Percutaneous transcatheter atrial septal defect closure with septal occluder device. Pectus excavatum, such as mental retardation or even cardiac abnormalities do not complain about aspects of the research must be done. Cardiac abnormalities regardless of the direction of the association needs to be done to show that we have a rigorous screening.
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Wed, 04 Mar 2015 23:56:45 GMT -08:00 http://www.scopemed.org/?mno=154823
Side effects of propofol:Itching and epilepsy http://www.scopemed.org/?mno=153707 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
Murat Parpucu, Elif Şenses.
Propofol with anesthesia is widely used especially for short duration of action and rare side effects of especially in day surgery. Patients with an abnormal movements after propofol administration and seizure-like activity have been reported.Induction with propofol for elective tubal ligation 28-year-old female patient after administration of propofol intravenously slowly redness in the head and neck region and the fast rhythmic movements of the head fro occurred.Patient go to after surgery service that we see covering all the neck under the chin stated that he felt a severe itching. In the present study we wanted to discuss along with itching in a focal region with rhythmic unwanted movements.
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Wed, 04 Mar 2015 23:56:45 GMT -08:00 http://www.scopemed.org/?mno=153707
EVALUATION OF ANALGESIC EFFECT OF CAUDAL ANAESTHESIA: A RETROSPECTIVE STUDY http://www.scopemed.org/?mno=154051 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
Nejla Mendil Erdoğan, Serdar Kaymak, mustafa uğuz, ömer çağatay ertugay, orhan yıldız, Mehtap GÜRLER BALTA.
Objective:We aimed to investigate the intraoperative and postoperative analgesic effect and complications of caudal anaesthesia in 27 patients who underwent circumcision performed after induction of general anesthesia, in 2013 from January to May. Materials and methods: 27 cases of circumsicion who underwent caudal blocking following general anaesthesia between 2013 January-May were retrospectively investigated. Anaesthesic follow-up forms and nursing observation charts of patients were examined. Demographic data, anesthetic agent that is used for induction and maintenance of anesthesia, duration of surgery, type of local anesthetic as well as its type and concentration, intraoperative and postoperative analgesic requirements, time of administration and complications were recorded. Results: Mean age was 4.9 ± 2.92 years of age ranging from 1 to 14 years and the average body weight was 19.55 ± 6.51 kg. All patients were administered 0.2% bupivacaine (0.8 ml/kg). Mean duration of surgery was 34.62 ± 4.61 minutes. duration. No analgesics were used intraoperatively and mean duration of postoperative analgesia was recoreded as 20.74 ± 7.25 hours. No complications were reported in the postoperative period. Conclusion:Caudal anaesthesia is an easily applied, safe and long-acting method in concordance with intraoperative and postoperative anaesthesia used in inguinal, urogenital and rectal pediatric surgery and it has an effective role in preventing complications. Keyword: Caudal block, analgesia, circumcision
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Wed, 04 Mar 2015 23:56:45 GMT -08:00 http://www.scopemed.org/?mno=154051
High-level maternal serum Alpha Feto Protein (AFP) and ultrasonography findings in second trimester pregnancies http://www.scopemed.org/?mno=160981 2015-03-06T20-21-51Z
Source: Journal of Contemporary Medicine
Bülent Çakmak, Zeki Özsoy, Fulya Zeynep Metin, Mehmet Can Nacar, Selim Gülücü, İsmail Sağ.
Objective: The aim of this study was to evaluate the findings of second trimester fetal anatomic ultrasound scan in pregnant women with high level Alpha Feto Protein (AFP) in triple test. Methods: Triple test results of 8552 pregnant women were evaluated in a university hospital between January 2011 and December 2013. Fetal anatomic ultrasound scan results of pregnant women who had AFP level ≥2.5 multiples of median (MoM) in triple test were investigated for presence of pathologic findings. Results: AFP levels were detected over 2.5 MoM in 122 (1.14%) of 8552 pregnant women. There were no pathologic findings in 85.2% (104/122) of cases, but 14.8% (18/122) of cases had pathologic results; neural tube defect (NTD) 9% (11/122) and anhidroamnios 2.5% (3/122). Omphalocele, polycystic kidney, sacrococcygeal teratoma, placental chorangioma were detected in 0.8% ratio. NTDs were found in 11 (0.12%) of 8552 pregnant women who evaluated for maternal serum AFP (MSAFP). Conclusion: The routine use of MSAFP may be queried in NTD screening due to common usage of sufficient fetal anatomic ultrasound scan.
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Wed, 04 Mar 2015 23:56:45 GMT -08:00 http://www.scopemed.org/?mno=160981