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Vet World. 2011; 4(2): 89-91

Ovarian stem cells and neo-oogenesis: A breakthrough in reproductive biology research

S. Mooyottu, S. Anees, S. Cherian.

The concept of ovarian stem cells which can replenish the ovarian reserve in postnatal mammalian females is a revolutionary breakthrough in reproductive biology. This idea overturned the central dogma existed in female reproductive physiology. Contradicting the popular belief that oogenesis does not occur in post natal life, researchers proved the existence of putative stem cells in ovary, which can supply functional follicles in post natal ovaries. Even though the idea of neo-oogenesis in postnatal ovaries in normal conditions is controversial, the isolation and manipulation of ovarian stem cells have got tremendous application in medical, veterinary and animal production fields.

Key words: Germline stem cells (GSC), Ovarian stem cells, Neo-oogenesis

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