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Brain metastasis from uterine malignancies: treatment modalities and prognostic factors

Naoual Benhmidou; Fadoua Rais; Abdellah Aissa; Otman Akkar; Khadija Bellahammou; Hasna Loughlimi; Abdelhak Maghous; Fadila Kouhen; Tayeb Kebdani; Hanan Elkacemi; Sanaa Elmajjaoui; Noureddine Benjaafar.

Abstract
Isolated brain metastases from gynecologic malignancies are unusual. Advances in therapeutic modalities including surgery, whole brain radiotherapy stereotactic radiosurgery and chemotherapy improved survival and quality of life in this population. Therapeutic decision is based on patients’ specific prognostic factors. We report three cases of isolated brain metastases from gynecologic cancers and discuss treatment modalities in the light of a literature review.

Key words: Brain metastasis;gynecologic malignancies;brain surgery;stereotactic radiosurgery;whole brain radiotherapy



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