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Validity and prognostic value of serum albumin level in emergency acute ischemic stroke egyptian patients

Adel Hamed Elbaih; Islam M Elshaboury; Rasha M Ahmed; Monira A Abd Allah.

Abstract
There are two main types of stroke: ischemic and hemorrhagic. Some studies showed the favorable relationship of serum albumin levels on the outcome of patients who suffer from ischemic stroke (IS). Some experimental studies have suggested a neuroprotective effect of albumin either by reducing brain edema or by its antioxidative or antiapoptotic effects. To detect serum albumin level and evaluate its prognostic value in patients with acute ischemic stroke in emergency department in compared to Scandinavian Stroke Scale (SSS). The study was carried out as descriptive (cross-sectional) study conducted on 60 patients with ischemic stroke attending emergency department in Suez Canal University hospital. It was found that all of died patients (100%) had hypoalbuminemia. While (92.5%) of patients who discharged from hospital had normal serum albumin level in follow up. but (7.5%) of them had hypoalbuminemia. And the ROC curve of both SSS and Serum albumin level on admission had Sensitivity: 100% and Specificity: 83% among studied patients. Thus serum albumin level has a direct correlation with short term prognosis of acute ischemic stroke patients. Patients with a lower SSS on admission and had higher levels of serum albumin had good short-term prognosis, and those with a high SSS and had a lower level of albumin had bad prognosis. higher levels of serum albumin is associated with a better short term prognosis. So they may act as indicators of short term prognosis.

Key words: Ischemic stroke IS;scandinavian stroke scale (SSS);serum albumin;outcome



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