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Düşünen Adam. 2006; 19(2): 103-109


Corpus Callosum Agenesis and Schizophrenia: A Case Report

Ahmet Kocabıyık, Hatice Alibaşoğlu, Nesrin Tomruk, Nihat Alpay.

Abstract
Partial or complete agenesis of the corpus callosum is a rare developmental anomaly of unknown cause. Corpus callosum plays an integrative role in the transmission of sensitive, motor and cognitive information coming from the homologous areas of the cerebral hemispheres. Abnormality in callosal transmission of perceptive stimuli is reported in schizophrenic patients. In this case report, a chronic schizophrenic patient with complete agenesis of corpus callosum is described. The interhemispheric transmission role of corpus callosum and its etiological implications in schizophrenia are discussed.

Key words: Corpus callosum, interhemispheric transmission, disconnection



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